Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Iriane Eger"'
Publikováno v:
BMC Cell Biology, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background The palmitate analogue 2-bromopalmitate (2-BP) is a non-selective membrane tethered cysteine alkylator of many membrane-associated enzymes that in the last years emerged as a general inhibitor of protein S-palmitoylation. Palmitoy
Externí odkaz:
https://doaj.org/article/ceb396da67a94ce6a1045848da346479
Autor:
Cassiano Martin Batista, Felipe Saad, Stephane Pini Costa Ceccoti, Iriane Eger, Maurilio José Soares
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 113, Iss 8 (2018)
Dynamic S-palmitoylation of proteins is the addition of palmitic acid by zDHHC palmitoyl transferases (PATs) and depalmitoylation by palmitoyl protein thioesterases (PPTs). A putative PAT (TcPAT1) has been previously identified in Trypanosoma cruzi,
Externí odkaz:
https://doaj.org/article/adf2474f3f384d15b0773573975e5090
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130165 (2015)
Epimastigote forms of Trypanosoma cruzi (the etiologic agent of Chagas disease) internalize and store extracellular macromolecules in lysosome-related organelles (LROs) called reservosomes, which are positive for the cysteine protease cruzipain. Desp
Externí odkaz:
https://doaj.org/article/35b1145bf3134fb699113ff616d6471e
Autor:
Mariel Asbury Marlow, Marise da Silva Mattos, Maria Ernestina Makowiecky, Iriane Eger, Andre Luiz Rossetto, Edmundo Carlos Grisard, Mário Steindel
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56177 (2013)
BACKGROUND: Although known to be highly endemic in the Amazon regions of Brazil, the presence of cutaneous leishmaniasis (CL) in the subtropical southern part of the country has largely been ignored. This study was conducted to demonstrate CL is emer
Externí odkaz:
https://doaj.org/article/3146234617cd4eea97316efab2033f37
Autor:
Ana Carolina Mello Fontoura de Souza, Julia Henneberg Hessman, Vitoria Scheffel Dias, Iriane Eger
Publikováno v:
Brazilian Medical Students. 7
Introdução: A esquistossomose é uma doença parasitária negligenciada, crônica e gradualmente debilitante, que mata 200 mil pessoas anualmente, segundo a Organização Mundial de Saúde. As estratégias atuais de controle da esquistossomose são
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90aa763dffeb698ba6de8bdc20616bc4
https://doi.org/10.53843/bms.v7i10.214
https://doi.org/10.53843/bms.v7i10.214
Publikováno v:
BMC Cell Biology
BMC Cell Biology, Vol 19, Iss 1, Pp 1-16 (2018)
BMC Cell Biology, Vol 19, Iss 1, Pp 1-16 (2018)
Background The palmitate analogue 2-bromopalmitate (2-BP) is a non-selective membrane tethered cysteine alkylator of many membrane-associated enzymes that in the last years emerged as a general inhibitor of protein S-palmitoylation. Palmitoylation is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3226e6a09b3833abbac91bb4a12f3230
https://pubmed.ncbi.nlm.nih.gov/30170543
https://pubmed.ncbi.nlm.nih.gov/30170543
Autor:
Rafael Luis Kessler, Iriane Eger, Maiko L. Tonini, Mauro V. de Almeida, Raquel Brandt Giordani, José Angelo S. Zuanazzi, Celina Noriko Yamanaka, Celso O. Rezende, Mário Steindel, Milene Höehr de Moraes, Débora R. R. P. Araujo
Publikováno v:
Chemical Biology & Drug Design. 82:697-704
Leishmanicidal and trypanocidal activity of seventeen lipophilic diamines was evaluated in vitro against Leishmania braziliensis, L. chagasi, and Trypanosoma cruzi. Twelve compounds presented anti-Leishmania and six showed anti-T. cruzi amastigote ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77d12223fa2e9997ced879ea92da528
https://doi.org/10.1111/cbdd.12191
https://doi.org/10.1111/cbdd.12191
Autor:
Guilherme Tadashi Hono Batista, Cassiano Martin Batista, Claudia Maria do Nascimento Moreira, Ligia Cristina Kalb, Iriane Eger, Maurilio J. Soares
Publikováno v:
Experimental Parasitology. 134:52-60
Protein palmitoylation is a post-translational modification that contributes to determining protein localization and function. Palmitoylation has been described in trypanosomatid protozoa, but no zDHHC palmitoyl transferase has been identified in Try
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49995b93ad36a197cf793c2d0deecaa6
https://doi.org/10.1016/j.exppara.2013.01.023
https://doi.org/10.1016/j.exppara.2013.01.023
Autor:
Mauricio Frota Saraiva, Thalita Cristina Alves Souza, Iriane Eger, Maria C.S. Lourenço, Mauro V. de Almeida, Dijovani Batista dos Reis, Adriano Barbosa
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 84
We report the synthesis of a series of diaminated terpenoids containing, as side-chain of the diamine core, the "head-to-tail" prenyl derivatives, with amino amino spacers of variable length. In vitro biological activity of these compounds was evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7fd5126a5f88edbbaac062732c0fe7
https://pubmed.ncbi.nlm.nih.gov/27876209
https://pubmed.ncbi.nlm.nih.gov/27876209
Autor:
Iriane Eger, Maurilio J. Soares
Publikováno v:
Journal of Microbiological Methods. 91:101-105
Here we describe the visualization by confocal microscopy of ingested gold (15 nm)-labeled transferrin in epimastigote forms of the protozoan Trypanosoma cruzi. Intracellular gold labeling was evident at two sites, which represent the bottom of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd868bf73546bec90c3c1c1007e1c24b
https://doi.org/10.1016/j.mimet.2012.07.013
https://doi.org/10.1016/j.mimet.2012.07.013