Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Irfan N. Bandey"'
Autor:
Melisa J. Montalvo, Irfan N. Bandey, Ali Rezvan, Kwan-Ling Wu, Arash Saeedi, Rohan Kulkarni, Yongshuai Li, Xingyue An, K M Samiur Rahman Sefat, Navin Varadarajan
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-14 (2024)
Abstract Chimeric antigen receptor (CAR) T cell show promise in cancer treatments, but their mechanism of action is not well understood. Decoding the mechanisms used by individual T cells can help improve the efficacy of T cells while also identifyin
Externí odkaz:
https://doaj.org/article/dcd48bed847c4f649497eacb88de0ec8
Autor:
Gabrielle Romain, Paolo Strati, Ali Rezvan, Mohsen Fathi, Irfan N. Bandey, Jay R T. Adolacion, Darren Heeke, Ivan Liadi, Mario L. Marques-Piubelli, Luisa M. Solis, Ankit Mahendra, Francisco Vega, Laurence J.N. Cooper, Harjeet Singh, Mike Mattie, Adrian Bot, Sattva S. Neelapu, Navin Varadarajan
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)
The in vivo persistence of adoptively transferred T cells is predictive of antitumor response. Identifying functional properties of infused T cells that lead to in vivo persistence and tumor eradication has remained elusive. We profiled CD19-specific
Externí odkaz:
https://doaj.org/article/22541142eb294d1693d8dcd42d53759f
Autor:
Navin Varadarajan, Ivan Liadi, Gabrielle Romain, Harjeet Singh, Arash Saeedi, Irfan N Bandey, Jay R T Adolacion, Melisa Martinez Paniagua, Xingyue An, Zheng You, Rasindu B Rajanayake, Laurence JN Cooper
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Adoptive cell therapy based on the infusion of chimeric antigen receptor (CAR) T cells has shown remarkable efficacy for the treatment of hematologic malignancies. The primary mechanism of action of these infused T cells is the direct kill
Externí odkaz:
https://doaj.org/article/0fec376a934743aab514c14f56cef78e
Autor:
Fatemeh Sadeghi, Irfan N Bandey, Xiaoyang Li, Badrinath Roysam, Navin Varadarajan, Monish Kumar
Publikováno v:
Biotechnol Bioeng
Ligand inducible proteins that enable precise and reversible control of nuclear translocation of passenger proteins have broad applications ranging from genetic studies in mammals to therapeutics that target diseases such as cancer and diabetes. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98d5385bafdbfd6d6495767a6473fe8
https://doi.org/10.1002/bit.27966
https://doi.org/10.1002/bit.27966
Autor:
Arash Saeedi, Irfan N. Bandey, Ankita Leekha, Mohsen Fathi, Ali Rezvan, Melisa J. Montalvo, Kwan-Ling Wu, Ritu Bohat, Weiyi Peng, Navin Varadarajan
Engineering cellular therapeutics by programming T cells has great potential in immunology. The primary mechanism employed by T cells for the specific transfer of proteins at the immunological synapse is via the lysosomal perforin pathway that facili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e3f6752dc7d0d1bf555b3784f5e58a8
https://doi.org/10.1101/2022.09.24.509028
https://doi.org/10.1101/2022.09.24.509028
Autor:
Ali Rezvan, Gabrielle Romain, Mohsen Fathi, Darren Heeke, Melisa Martinez-Paniagua, Xingyue An, Irfan N Bandey, Arash Saeedi, Fatemeh Sadeghi, Kristen Fousek, Nahum Puebla-Osorio, Laurence J.N. Cooper, Chantale Bernatchez, Harjeet Singh, Nabil Ahmed, Mike Mattie, Adrian Bot, Sattva Neelapu, Navin Varadarajan
Adoptive immunotherapy with T cells expressing chimeric antigen receptors (CARs) for B-cell malignancies serves as a model for identifying subsets with superior clinical activity. We profiled the infusion products (IP) of 16 patients with large B-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35180ccb13071643029787dcd3249eac
https://doi.org/10.1101/2022.06.22.497245
https://doi.org/10.1101/2022.06.22.497245
Autor:
Gabrielle Romain, Paolo Strati, Ali Rezvan, Mohsen Fathi, Irfan N Bandey, Jay R T Adolacion, Darren Heeke, Ivan Liadi, Mario L Marques-Piubelli, Luisa M. Solis, Ankit Mahendra, Francisco Vega, Laurence J.N. Cooper, Harjeet Singh, Mike Mattie, Adrian Bot, Sattva Neelapu, Navin Varadarajan
The in vivo persistence of adoptively transferred T cells is predictive of anti-tumor response. Identifying functional properties of infused T cells that lead to in vivo persistence and tumor eradication has remained elusive. We profiled CD19-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::921728699a9ff2dc9e9101e827d2c8e7
https://doi.org/10.1101/2022.02.11.479825
https://doi.org/10.1101/2022.02.11.479825
Autor:
Rasindu B. Rajanayake, Ivan Liadi, Patrick Hwu, Irfan N Bandey, Jay R Adolacion, Arash Saeedi, Harjeet Singh, Navin Varadarajan, Zheng You, Gabrielle Romain, Melisa Martinez Paniagua, Xingyue An, Laurence J.N. Cooper
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundAdoptive cell therapy based on the infusion of chimeric antigen receptor (CAR) T cells has shown remarkable efficacy for the treatment of hematologic malignancies. The primary mechanism of action of these infused T cells is the direct killi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30cb1e62007f663cddeccd2484ecaf3
https://jitc.bmj.com/content/9/3/e001877.full
https://jitc.bmj.com/content/9/3/e001877.full
Autor:
Thiago Aparecido da Silva, Amer Najjar, Tamara Laskowski, Qi Wang, Pappanaicken R. Kumaresan, Paul J. Hauser, Irfan N Bandey
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Background aims The genus Cryptococcus comprises two major fungal species that cause clinical infections in humans: Cryptococcus gattii and Cryptococcus neoformans. To establish invasive human disease, inhaled cryptococci must penetrate the lung tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf365d056591129d48e7cd78a5593a6
Autor:
Ali Rezvan, Gabrielle Romain, Mohsen Fathi, Darren Heeke, Melisa Martinez-Paniagua, Xingyue An, Irfan N Bandey, Ivan Liadi, Laurence J.N. Cooper, Harjeet Singh, Adrian Bot, Sattva Neelapu, Navin Varadarajan
Publikováno v:
The Journal of Immunology. 208:54.18-54.18
T-cell therapy with specificity redirected through chimeric antigen receptors (CARs) has shown efficacy for the treatment of hematologic malignancies. Although treatment with CAR T cell can result in high response rates, the properties of the cells t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46c5010b3eab28359a8248d754471a30
https://doi.org/10.4049/jimmunol.208.supp.54.18
https://doi.org/10.4049/jimmunol.208.supp.54.18