Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Irene-Ariadne Kechagia"'
Autor:
Stavros Tzimas, Eirini Christodoulou, Nikolaos Kostomitsopoulos, Evangelos Balafas, Aristides Dokoumetzidis, Irene-Ariadne Kechagia, H.A. Archontaki, Georgia Valsami
Publikováno v:
International Journal of Pharmaceutics. 493:366-373
Silibinin, the main active component of Silybum marianum is a hepatoprotective and antioxidant agent with antitumor effect, exhibiting very low aqueous solubility and oral bioavailability limiting its use in therapeutics. We characterized serum and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a7ad68e19608464429c754ea1ae039
https://doi.org/10.1016/j.ijpharm.2015.07.060
https://doi.org/10.1016/j.ijpharm.2015.07.060
Publikováno v:
Journal of Pharmacy and Pharmacology. 67:1537-1545
Objectives To extrapolate enalapril efficacy to children 0–6 years old, a pharmacokinetic/pharmacodynamic (PKPD) model was built using literature data, with blood pressure as the PD endpoint. Methods A PK model of enalapril was developed from liter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e35cd2bcb973c052d53465447b6b05d
https://doi.org/10.1111/jphp.12471
https://doi.org/10.1111/jphp.12471
Publikováno v:
The Pediatric infectious disease journal. 34(12)
Background Valacyclovir is a prodrug of acyclovir. Although acyclovir is approved for children in Europe, valacyclovir is not approved, despite being used off-label. The aim of the study was to extrapolate the approved dosages of acyclovir, to valacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7131f97f9f56c0509cc1a1c7b1809f19
https://pubmed.ncbi.nlm.nih.gov/26379165
https://pubmed.ncbi.nlm.nih.gov/26379165
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics. 42(3)
A preliminary population pharmacokinetic (PopPK) model of valacyclovir in children was developed from non-compartmental analysis (NCA) parameter values from literature, including several age groups, combined with Bayesian priors from a PopPK model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8fb1181864d6f9956e2ede69cf212b
https://pubmed.ncbi.nlm.nih.gov/25821006
https://pubmed.ncbi.nlm.nih.gov/25821006
Akademický článek
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Publikováno v:
Journal of Pharmacy & Pharmacology; Nov2015, Vol. 67 Issue 11, p1537-1545, 9p
Publikováno v:
Pediatric Infectious Disease Journal; Dec2015, Vol. 34 Issue 12, p1342-1348, 7p
Publikováno v:
Journal of Pharmacokinetics & Pharmacodynamics; Jun2015, Vol. 42 Issue 3, p237-250, 14p
Publikováno v:
European Journal of Drug Metabolism & Pharmacokinetics; Dec2017, Vol. 42 Issue 6, p879-880, 2p