Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Irene Yujnovsky"'
Publikováno v:
Hypertension. 44:783-787
Release of norepinephrine (NE) by the hypothalamic nuclei may contribute to regulation of sympathetic nervous system (SNS) activity. Angiotensin-(1–7) [Ang-(1–7)] has an antihypertensive effect and may decrease SNS activity. We tested the hypothe
Publikováno v:
Current Biology. 14:975-980
Light-dependent transcriptional regulation of clock genes is a crucial step in the entrainment of the circadian clock. E4bp4 is a light-inducible gene in the chick pineal gland, and it encodes a bZIP protein that represses transcription of cPer2, a c
Publikováno v:
Regulatory Peptides. 118:45-49
Since it has been suggested that angiotensin (Ang) (1–7) functions as an antihypertensive peptide, we studied its effect on the Ang II-enhanced norepinephrine (NE) release evoked by K+ in hypothalami isolated from aortic coarcted hypertensive (CH)
Autor:
Luca Cardone, Irene Yujnovsky, Matthew P. Pando, David Morse, Masao Doi, Nicolas Cermakian, Paolo Sassone-Corsi
Publikováno v:
Molecular Clocks and Light Signalling: Novartis Foundation Symposium 253
Circadian rhythms are regulated by clocks located in specific structures of the CNS, such as the suprachiasmatic nucleus (SCN) in mammals, and by peripheral oscillators present in various other tissues. The expression of essential clock genes oscilla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c1841b1af7d89f5e4ff05f3b443814
https://doi.org/10.1002/0470090839.ch10
https://doi.org/10.1002/0470090839.ch10
Autor:
Sehyung Cho, Irene Yujnovsky, Nicolas Cermakian, Paolo Sassone-Corsi, Andrew C.B. Cato, Jun Hirayama, Masao Doi
Publikováno v:
Journal of Biological Rhythms
Journal of Biological Rhythms, SAGE Publications, 2007, 22 (2), pp.127-39. ⟨10.1177/0748730406298332⟩
Journal of Biological Rhythms, SAGE Publications, 2007, 22 (2), pp.127-39. ⟨10.1177/0748730406298332⟩
MAP kinase phosphatase 1 (MKP1) is a negative regulator for the mitogen-activated protein kinase (MAPK)—mediated signal transduction, a key pathway that leads to the regulated expression of circadian clock genes. Here the authors analyzed mkp1 expr
Autor:
Masao Doi, Emanuele Tirotta, Monica Malerba, Irene Yujnovsky, Paolo Sassone-Corsi, Jun Hirayama, Emiliana Borrelli
Publikováno v:
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2006, 9 (6), pp.732-4. ⟨10.1038/nn1711⟩
Nature Neuroscience, Nature Publishing Group, 2006, 9 (6), pp.732-4. ⟨10.1038/nn1711⟩
International audience; Disruption of overt circadian rhythms can occur without influencing the endogenous pacemaker, the so-called 'masking' effect classically elicited by light. As the physiological pathways involved in light masking remain elusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37aafd0086218db8acb0075cf3b6c61d
https://hal.archives-ouvertes.fr/hal-00187891
https://hal.archives-ouvertes.fr/hal-00187891
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (16), pp.6386-91. ⟨10.1073/pnas.0510691103⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (16), pp.6386-91. ⟨10.1073/pnas.0510691103⟩
Environmental cues modulate a variety of intracellular pathways whose signaling is integrated by the molecular mechanism that constitutes the circadian clock. Although the essential gears of the circadian machinery have been elucidated, very little i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b95e157f4e9c0706d0246e54d989bc1
https://hal.archives-ouvertes.fr/hal-00188235
https://hal.archives-ouvertes.fr/hal-00188235
Autor:
Özkan Yildiz, Eva Wolf, Masao Doi, Sabrina Schulze, Irene Yujnovsky, Paolo Sassone-Corsi, Alex Berndt, Sven Hennig, Luca Cardone, Claus Urbanke
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2005, 17 (1), pp.69-82. ⟨10.1016/j.molcel.2004.11.022⟩
Molecular Cell, 17(1), 69-82. Cell Press
Yildiz, O, Doi, M, Yujnovsky, I, Cardone, L, Berndt, A, Hennig, S, Schulze, S, Urbanke, C, Sassone-Corsi, P & Wolf, E 2005, ' Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD ', Molecular Cell, vol. 17, no. 1, pp. 69-82 . https://doi.org/10.1016/j.molcel.2004.11.022
Molecular Cell, Elsevier, 2005, 17 (1), pp.69-82. ⟨10.1016/j.molcel.2004.11.022⟩
Molecular Cell, 17(1), 69-82. Cell Press
Yildiz, O, Doi, M, Yujnovsky, I, Cardone, L, Berndt, A, Hennig, S, Schulze, S, Urbanke, C, Sassone-Corsi, P & Wolf, E 2005, ' Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD ', Molecular Cell, vol. 17, no. 1, pp. 69-82 . https://doi.org/10.1016/j.molcel.2004.11.022
International audience; PERIOD proteins are central components of the Drosophila and mammalian circadian clock. Their function is controlled by daily changes in synthesis, cellular localization, phosphorylation, degradation, as well as specific inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea9a319a8771978b72aaabc6ec7b1320
https://hal.archives-ouvertes.fr/hal-00187803
https://hal.archives-ouvertes.fr/hal-00187803
One of the unresolved issues in the field of circadian biology is dissection of the communication pathways between central and peripheral oscillators. We have developed an experimental procedure in which an implant of mouse embryo fibroblasts of a sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e7e7d1ec94e4ab6849e45607c2bb907
https://doi.org/10.1016/s0076-6879(05)93023-1
https://doi.org/10.1016/s0076-6879(05)93023-1
Autor:
Nicolas, Cermakian, Matthew P, Pando, Masao, Doi, Luca, Cardone, Irene, Yujnovsky, David, Morse, Paolo, Sassone-Corsi
Publikováno v:
Novartis Foundation symposium. 253
Circadian rhythms are regulated by clocks located in specific structures of the CNS, such as the suprachiasmatic nucleus (SCN) in mammals, and by peripheral oscillators present in various other tissues. The expression of essential clock genes oscilla