Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Irene Y. Xie"'
1
Abstract 173: Genomic characterization of patient-derived pancreatic cancer organoids
Autor: Irene Y. Xie, Yuanchang Fang, Amy X. Zhang, Karen Ng, Zhen-Mei Liu, Eugenia Flores-Figueroa, Gun Ho Jang, Stephanie Ramotar, Anna Dodd, Julie Wilson, Jennifer J. Knox, Steven Gallinger, Faiyaz Notta
Publikováno v: Cancer Research. 83:173-173
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer death with few effective therapies. Patient-derived organoids (PDOs) are a 3-D culture model that allow primary tumour cells to propagate, and have gained considerable traction in m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed04e2be2c6cda235e4e908332d63b83
https://doi.org/10.1158/1538-7445.am2023-173
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2
Akademický článek
Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract.
Autor: Alexander S Zevin, Irene Y Xie, Kenzie Birse, Kelly Arnold, Laura Romas, Garrett Westmacott, Richard M Novak, Stuart McCorrister, Lyle R McKinnon, Craig R Cohen, Romel Mackelprang, Jairam Lingappa, Doug A Lauffenburger, Nichole R Klatt, Adam D Burgener
Publikováno v: PLoS Pathogens, Vol 12, Iss 9, p e1005889 (2016)
The mechanism(s) by which bacterial communities impact susceptibility to infectious diseases, such as HIV, and maintain female genital tract (FGT) health are poorly understood. Evaluation of FGT bacteria has predominantly been limited to studies of s
Externí odkaz: https://doaj.org/article/20431824830346c0951f09ead965baef
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3
Abstract A064: High-throughput organoid drug screening to identify molecular vulnerabilities in pancreatic cancer
Autor: Irene Y Xie, Zhen-Mei Liu, Karen Ng, Eugenia Flores-Figueroa, Gun Ho Jang, Amy X. Zhang, Stephanie Ramotar, Anna Dodd, Julie Wilson, Grainne M. O'Kane, Jennifer J. Knox, Steven Gallinger, Faiyaz Notta
Publikováno v: Cancer Research. 82:A064-A064
Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer that typically presents at the advanced or metastatic stage. Although some patients achieve partial responses with chemotherapy, most tumors progress rapidly and become resistant to therapy.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d258d7f70f18ad46b410f2d565d74710
https://doi.org/10.1158/1538-7445.panca22-a064
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4
Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women
Autor: Adam Burgener, Irene Y. Xie, Quarraisha Abdool Karim, Salim S. Abdool Karim, Alexander S. Zevin, Nichole R. Klatt, Michelle Perner, Laura Noël-Romas, Jennifer. Butler, Lyle R. McKinnon, Leila E. Mansoor, Anna Christina. Grobler, Kenzie Birse, Jo-Ann S. Passmore, Garrett Westmacott, Ryan Cheu
Publikováno v: Science. 356:938-945
Antiretroviral-based strategies for HIV prevention have shown inconsistent results in women. We investigated whether vaginal microbiota modulated tenofovir gel microbicide efficacy in the CAPRISA (Centre for the AIDS Program of Research in South Afri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6896faf52c60ab62adabac038b3674
https://doi.org/10.1126/science.aai9383
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5
The genomic landscape of recurrent pancreatic cancer is modified by treatment
Autor: Steven Gallinger, Irene Y. Xie
Publikováno v: Nature Reviews Gastroenterology & Hepatology. 17:389-390
Most patients who undergo curative intent surgery for pancreatic cancer will still die of recurrent disease. A new study shows that pancreatic tumours that pass through the genetic bottlenecks of surgery and additional chemoradiotherapy have altered
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0931db00f6babac088c5aca94bd8723
https://doi.org/10.1038/s41575-020-0321-9
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6
Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8 + T Cells by the Sheddase ADAM10, Is Increased in Plasma during Untreated HIV Infection, and Correlates with HIV Disease Progression
Autor: A. K. M. Nur-ur Rahman, Lishomwa C. Ndhlovu, Mario A. Ostrowski, Marion C. Lanteri, Steven G. Deeks, Matthew Douglas-Vail, Glen M. Chew, Philip J. Norris, Kiera L. Clayton, Irene Y. Xie, Ravi Tandon, Karyn E. Medcalf
Publikováno v: Journal of virology, vol 89, iss 7
Chronic HIV infection results in a loss of HIV-specific CD8 + T cell effector function, termed “exhaustion,” which is mediated, in part, by the membrane coinhibitory receptor T cell immunoglobulin mucin domain-3 (Tim-3). Like many other receptors
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b55a65bc648ad7c0bc3cebea30d43d
https://doi.org/10.1128/jvi.00006-15
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7
HIVR4P 2016, Partnering for Prevention: Conference Summary and Highlights
Autor: Jeanne M. Marrazzo, Damien C. Tully, Constantinos Kurt Wibmer, Nelly Mugo, Thomas J. Hope, Raphael J. Landovitz, Srinika Ranasinghe, Irene Y. Xie, Yegor Voronin, Kenneth Ngure, Bargavi Thyagarajan, Gabriella Scarlatti, Elise Landais, Barbara L. Shacklett, Colin Anthony, Morenike Oluwatoyin Folayan, Lorna Leal, Mitchell Warren, Anna-Janina Behrens, Cynthia A. Derdeyn, Lynn Morris, Veronica Noseda
Publikováno v: AIDS research and human retroviruses, vol 33, iss 8
AIDS Research and Human Retroviruses
Shacklett, BL; Derdeyn, CA; Folayan, MO; Landovitz, RJ; Anthony, C; Behrens, AJ; et al.(2017). HIVR4P 2016, Partnering for Prevention: Conference Summary and Highlights. AIDS Research and Human Retroviruses, 33(8), 749-759. doi: 10.1089/aid.2017.0125. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/4ts3b696
© 2017 Barbara L. Shacklett t al. HIV Research for Prevention: AIDS Vaccine, Microbicide, and ARV-based Prevention Science (HIVR4P) was built on a growing consensus that effective HIV prevention requires a combination of approaches and that understa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfd4fba8383f04a11311c15026cb3e9
https://escholarship.org/uc/item/4ts3b696
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8
Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract
Autor: Adam Burgener, Craig R. Cohen, Lyle R. McKinnon, Richard M. Novak, Kelly B. Arnold, Irene Y. Xie, Garrett Westmacott, Jairam R. Lingappa, Alexander S. Zevin, Stuart McCorrister, Doug A. Lauffenburger, Nichole R. Klatt, Laura Romas, Kenzie Birse, Romel D. Mackelprang
Publikováno v: PLoS Pathogens, Vol 12, Iss 9, p e1005889 (2016)
PLoS pathogens, vol 12, iss 9
PLoS Pathogens
PLoS
The mechanism(s) by which bacterial communities impact susceptibility to infectious diseases, such as HIV, and maintain female genital tract (FGT) health are poorly understood. Evaluation of FGT bacteria has predominantly been limited to studies of s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a663811fd0102d3c433c5c73b0e6a294
http://europepmc.org/articles/PMC5033340?pdf=render
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