Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Irene Wuethrich"'
The role of the human gut microbiota in colonization and infection with multidrug-resistant bacteria
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
About 100 years ago, the first antibiotic drug was introduced into health care. Since then, antibiotics have made an outstanding impact on human medicine. However, our society increasingly suffers from collateral damage exerted by these highly effect
Externí odkaz:
https://doaj.org/article/9c79834a9b1e48ea99b46744765df0f2
Autor:
Irene Wuethrich, Janneke G C Peeters, Annet E M Blom, Christopher S Theile, Zeyang Li, Eric Spooner, Hidde L Ploegh, Carla P Guimaraes
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109883 (2014)
Aerolysin is a secreted bacterial toxin that perforates the plasma membrane of a target cell with lethal consequences. Previously explored native and epitope-tagged forms of the toxin do not allow site-specific modification of the mature toxin with a
Externí odkaz:
https://doaj.org/article/e7c5298442ba4a569a0e3bf5e40dec51
Autor:
Laura W Harris, Matthew Wayland, Martin Lan, Margaret Ryan, Thomas Giger, Helen Lockstone, Irene Wuethrich, Michael Mimmack, Lan Wang, Mark Kotter, Rachel Craddock, Sabine Bahn
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3964 (2008)
BackgroundPrevious studies of brain and peripheral tissues in schizophrenia patients have indicated impaired energy supply to the brain. A number of studies have also demonstrated dysfunction of the microvasculature in schizophrenia patients. Togethe
Externí odkaz:
https://doaj.org/article/70b2569b333d4519a25dae37fa881661
Autor:
Stefanie K. Gräfe, Maria J G T Vehreschild, Anastasia Tsakmaklis, Alina M Rüb, Irene Wuethrich, Marie-Christine Simon
Publikováno v:
Biomarkers in medicine. 15(2)
The association of gut microbiota dysbiosis with various human diseases is being substantiated with increasing evidence. Metabolites derived from both, microbiota and the human host play a central role in disease susceptibility and disease progressio
The role of the human gut microbiota in colonization and infection with multidrug-resistant bacteria
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Gut Microbes, 13 (1)
Gut Microbes
article-version (VoR) Version of Record
Gut Microbes, 13 (1)
Gut Microbes
article-version (VoR) Version of Record
About 100 years ago, the first antibiotic drug was introduced into health care. Since then, antibiotics have made an outstanding impact on human medicine. However, our society increasingly suffers from collateral damage exerted by these highly effect
Publikováno v:
Advances in applied microbiology. 101
Prokaryotes modified stably on the genome are of great importance for production of fine and commodity chemicals. Traditional methods for genome engineering have long suffered from imprecision and low efficiencies, making construction of suitable hig
Prokaryotes modified stably on the genome are of great importance for production of fine and commodity chemicals. Traditional methods for genome engineering have long suffered from imprecision and low efficiencies, making construction of suitable hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cfeb5af72aa847e0f8943cdf496096a
https://doi.org/10.1016/bs.aambs.2017.07.001
https://doi.org/10.1016/bs.aambs.2017.07.001
Autor:
George W. Bell, Carla P. Guimaraes, Sebastian M.B. Nijman, Vincent A. Blomen, Irene Wuethrich, Markus K Muellner, Jan E. Carette, Hidde L. Ploegh, Chong-Jing Sun, Bingbing Yuan, Thijn R Brummelkamp, Malini Varadarajan
Publikováno v:
Nature biotechnology
Insertional mutagenesis in a haploid background can disrupt gene function. We extend our earlier work by using a retroviral gene-trap vector to generate insertions in >98% of the genes expressed in a human cancer cell line that is haploid for all but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dcc97d5788d4e72919358be4e372fd
https://ora.ox.ac.uk/objects/uuid:353c91df-4016-4a32-b9d2-39ebd43588eb
https://ora.ox.ac.uk/objects/uuid:353c91df-4016-4a32-b9d2-39ebd43588eb
Autor:
Thijn R. Brummelkamp, Brent H. Cochran, Irene Wuethrich, Carla P. Guimaraes, Jan E. Carette, Annie S. Park, Maciej Kotecki, Malini Varadarajan, Eric Spooner, Alzbeta Godarova, Hidde L. Ploegh
Publikováno v:
Science. 326:1231-1235
“Haploid Human” Genetic screens can provide direct insight into biological processes that are poorly understood. Carette et al. (p. 1231 ) describe genetic screens using large-scale gene disruption in human cells haploid for all chromosomes excep
Publikováno v:
Monoclonal antibodies in immunodiagnosis and immunotherapy. 33(2)
Fluorophores are essential tools in molecular and cell biology. However, their application is mostly confined to the singular exploitation of their fluorescent properties. To enhance the versatility and expand the use of the fluorophore Alexa Fluor 6