Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Irene Villalón-García"'
Autor:
Marta Talaverón-Rey, Mónica Álvarez-Córdoba, Irene Villalón-García, Suleva Povea-Cabello, Juan M. Suárez-Rivero, David Gómez-Fernández, Ana Romero-González, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Paula Cilleros-Holgado, Diana Reche-López, Rocío Piñero-Pérez, José A. Sánchez-Alcázar
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-23 (2023)
Abstract Background Neurodegeneration with brain iron accumulation (NBIA) disorders are a group of neurodegenerative diseases that have in common the accumulation of iron in the basal nuclei of the brain which are essential components of the extrapyr
Externí odkaz:
https://doaj.org/article/a9c9d7d4ff2e4fdeafccf4fbfe00f6d4
Autor:
Irene Villalón-García, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Marta Talaverón-Rey, Juan M Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Pérez, José A Sánchez-Alcázar
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 6, Pp 1196-1202 (2023)
Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders. Mitochondrial dysfunction
Externí odkaz:
https://doaj.org/article/6b03972c86ee4badb530ea9449247808
Autor:
Mónica Álvarez-Córdoba, Diana Reche-López, Paula Cilleros-Holgado, Marta Talaverón-Rey, Irene Villalón-García, Suleva Povea-Cabello, Juan M. Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Rocío Piñero-Pérez, José A. Sánchez-Alcázar
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-16 (2022)
Abstract Background Neurodegeneration with brain iron accumulation (NBIA) is a group of rare neurogenetic disorders frequently associated with iron accumulation in the basal nuclei of the brain characterized by progressive spasticity, dystonia, muscl
Externí odkaz:
https://doaj.org/article/25dc1fcca1da406d810dd2635ade6c2f
Autor:
Juan M. Suárez-Rivero, Carmen J. Pastor-Maldonado, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Irene Villalón-García, Marta Talaverón-Rey, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Perez, José A. Sánchez-Alcázar
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-23 (2022)
Abstract Background Mitochondrial diseases represent one of the most common groups of genetic diseases. With a prevalence greater than 1 in 5000 adults, such diseases still lack effective treatment. Current therapies are purely palliative and, in mos
Externí odkaz:
https://doaj.org/article/36b1121325ae4a249c38c5ee37bf18fa
Autor:
Mónica Álvarez-Córdoba, Marta Talaverón-Rey, Irene Villalón-García, Suleva Povea-Cabello, Juan M. Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Joaquín J. Salas, José A. Sánchez-Alcázar
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-16 (2021)
Abstract Background Neurodegeneration with brain iron accumulation (NBIA) is a group of genetic neurological disorders frequently associated with iron accumulation in the basal nuclei of the brain characterized by progressive spasticity, dystonia, mu
Externí odkaz:
https://doaj.org/article/6bc379513f8b46b78c586b7fa2c6900e
Autor:
Irene Villalón-García, Mónica Álvarez-Córdoba, Suleva Povea-Cabello, Marta Talaverón-Rey, Marina Villanueva-Paz, Raquel Luzón-Hidalgo, Juan M. Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Joaquín J. Salas, Rafael Falcón-Moya, Antonio Rodríguez-Moreno, José A. Armengol, José A. Sánchez-Alcázar
Publikováno v:
Neurobiology of Disease, Vol 165, Iss , Pp 105649- (2022)
Background: PLA2G6-Associated Neurodegeneration (PLAN) is a rare neurodegenerative disease with autosomal recessive inheritance, which belongs to the NBIA (Neurodegeneration with Brain Iron Accumulation) group. Although the pathogenesis of the diseas
Externí odkaz:
https://doaj.org/article/7c54399a42554a24a0660b56caed3833
Autor:
Juan M. Suárez-Rivero, Carmen J. Pastor-Maldonado, Ana Romero-González, David Gómez-Fernandez, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Irene Villalón-García, Marta Talaverón-Rey, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, José A. Sánchez-Alcázar
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Mitochondrial diseases are genetic disorders caused by mutations in genes in the nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) that encode mitochondrial structural or functional proteins. Although considered “rare” due to their low incidence,
Externí odkaz:
https://doaj.org/article/137e3b95f7344feabec2bf2b74fa35c0
Autor:
Mónica Alvarez-Cordoba, Marina Villanueva-Paz, Irene Villalón-García, Suleva Povea-Cabello, Juan M Suárez-Rivero, Marta Talaverón-Rey, Javier Abril-Jaramillo, Ana Belén Vintimilla-Tosi, José A Sánchez-Alcázar
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 7, Pp 1177-1185 (2019)
Neurodegeneration with brain iron accumulation is a broad term that describes a heterogeneous group of progressive and invalidating neurologic disorders in which iron deposits in certain brain areas, mainly the basal ganglia. The predominant clinical
Externí odkaz:
https://doaj.org/article/cad13e0d43f341b486e2d44e0537c2a5
Autor:
Juan M. Suárez-Rivero, Carmen J. Pastor-Maldonado, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Irene Villalón-García, Marta Talaverón-Rey, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Pérez, José A. Sánchez-Alcázar
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1611 (2022)
Mitochondrial dysfunction is a key hub that is common to many diseases. Mitochondria’s role in energy production, calcium homeostasis, and ROS balance makes them essential for cell survival and fitness. However, there are no effective treatments fo
Externí odkaz:
https://doaj.org/article/428ed39d6e2e49c2932163677627e8ff
Autor:
Candela Machuca, Marta Correa-Vela, Deyanira García-Navas, Alejandra Darling, Irene Villalón-García, José Antonio Sánchez-Alcázar, Belén Pérez-Dueñas, Slaven Erceg, Carmen Espinós
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102338- (2021)
The human iPSC cell lines, PLANFiPS1-Sv4F-1 (RCPFi004-A), PLANFiPS2-Sv4F-1 (RCPFi005-A), PLANFiPS3-Sv4F-1 RCPFi006-A), derived from dermal fibroblast from three patients suffering PLAN (PLA2G6-associated neurodegeneration; MIM 256600) caused by mutat
Externí odkaz:
https://doaj.org/article/1a353abcb7a84e1589a0d39f34e813f1