Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Irene V Bijnsdorp"'
Autor:
Sofie Bosch, Animesh Acharjee, Mohammed Nabil Quraishi, Irene V Bijnsdorp, Patricia Rojas, Abdellatif Bakkali, Erwin EW Jansen, Pieter Stokkers, Johan Kuijvenhoven, Thang V Pham, Andrew D Beggs, Connie R Jimenez, Eduard A Struys, Georgios V Gkoutos, Tim GJ de Meij, Nanne KH de Boer
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Background Screening for colorectal cancer (CRC) reduces its mortality but has limited sensitivity and specificity. Aims We aimed to explore potential biomarker panels for CRC and adenoma detection and to gain insight into the interaction between gut
Externí odkaz:
https://doaj.org/article/7b47430b742b473c9f1e78bcdb4e406c
Autor:
Elisa Suárez-Martínez, Sander R. Piersma, Thang V. Pham, Irene V. Bijnsdorp, Connie R. Jimenez, Amancio Carnero
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Ovarian cancer has a high mortality rate mainly due to its resistance to currently used therapies. This resistance has been associated with the presence of cancer stem cells (CSCs), interactions with the microenvironment, and intr
Externí odkaz:
https://doaj.org/article/af08a23f399f4704a81219517ab21154
Autor:
Alexia Gali, Irene V. Bijnsdorp, Sander R. Piersma, Thang V. Pham, Elena Gutiérrez-Galindo, Fiona Kühnel, Nikos Tsolakos, Connie R. Jimenez, Angelika Hausser, Leonidas G. Alexopoulos
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108958- (2024)
Summary: The protein kinase D (PKD) family members regulate the fission of cargo vesicles at the Golgi complex and play a pro-oncogenic role in triple-negative breast cancer (TNBC). Whether PKD facilitates the secretion of tumor-promoting factors in
Externí odkaz:
https://doaj.org/article/85599656f67044cbafb566e2492ace42
Autor:
Tiansheng Zhu, Yi Zhu, Yue Xuan, Huanhuan Gao, Xue Cai, Sander R. Piersma, Thang V. Pham, Tim Schelfhorst, Richard R.G.D. Haas, Irene V. Bijnsdorp, Rui Sun, Liang Yue, Guan Ruan, Qiushi Zhang, Mo Hu, Yue Zhou, Winan J. Van Houdt, Tessa Y.S. Le Large, Jacqueline Cloos, Anna Wojtuszkiewicz, Danijela Koppers-Lalic, Franziska Böttger, Chantal Scheepbouwer, Ruud H. Brakenhoff, Geert J.L.H. van Leenders, Jan N.M. Ijzermans, John W.M. Martens, Renske D.M. Steenbergen, Nicole C. Grieken, Sathiyamoorthy Selvarajan, Sangeeta Mantoo, Sze S. Lee, Serene J.Y. Yeow, Syed M.F. Alkaff, Nan Xiang, Yaoting Sun, Xiao Yi, Shaozheng Dai, Wei Liu, Tian Lu, Zhicheng Wu, Xiao Liang, Man Wang, Yingkuan Shao, Xi Zheng, Kailun Xu, Qin Yang, Yifan Meng, Cong Lu, Jiang Zhu, Jin'e Zheng, Bo Wang, Sai Lou, Yibei Dai, Chao Xu, Chenhuan Yu, Huazhong Ying, Tony K. Lim, Jianmin Wu, Xiaofei Gao, Zhongzhi Luan, Xiaodong Teng, Peng Wu, Shi'ang Huang, Zhihua Tao, Narayanan G. Iyer, Shuigeng Zhou, Wenguang Shao, Henry Lam, Ding Ma, Jiafu Ji, Oi L. Kon, Shu Zheng, Ruedi Aebersold, Connie R. Jimenez, Tiannan Guo
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 18, Iss 2, Pp 104-119 (2020)
To address the increasing need for detecting and validating protein biomarkers in clinical specimens, mass spectrometry (MS)-based targeted proteomic techniques, including the selected reaction monitoring (SRM), parallel reaction monitoring (PRM), an
Externí odkaz:
https://doaj.org/article/272efeb3b0fc4ac9a3ba92b579d82fb4
Autor:
Xue D. Manz, Robert Szulcek, Xiaoke Pan, Petr Symersky, Chris Dickhoff, Jisca Majolée, Veerle Kremer, Elisabetta Michielon, Ekaterina S. Jordanova, Teodora Radonic, Irene V. Bijnsdorp, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Anton Vonk Noordegraaf, Frances S. de Man, Reinier A. Boon, Jan Voorberg, Peter L. Hordijk, Jurjan Aman, Harm Jan Bogaard
Publikováno v:
American journal of respiratory and critical care medicine, 205(7), 808-818. American Thoracic Society
Manz, X D, Szulcek, R, Pan, X, Symersky, P, Dickhoff, C, Majolee, J, Kremer, V, Michielon, E, Jordanova, E S, Radonic, T, Bijnsdorp, I V, Piersma, S R, Pham, T V, Jimenez, C R, Noordegraaf, A V, de Man, F S, Boon, R A, Voorberg, J, Hordijk, P L, Aman, J & Bogaard, H J 2022, ' Epigenetic Modification of the von Willebrand Factor Promoter Drives Platelet Aggregation on the Pulmonary Endothelium in Chronic Thromboembolic Pulmonary Hypertension ', American Journal of Respiratory and Critical Care Medicine, vol. 205, no. 7, pp. 806-818 . https://doi.org/10.1164/rccm.202109-2075OC
American Journal of Respiratory and Critical Care Medicine, 205(7), 806-818. American Thoracic Society
Manz, X D, Szulcek, R, Pan, X, Symersky, P, Dickhoff, C, Majolee, J, Kremer, V, Michielon, E, Jordanova, E S, Radonic, T, Bijnsdorp, I V, Piersma, S R, Pham, T V, Jimenez, C R, Noordegraaf, A V, de Man, F S, Boon, R A, Voorberg, J, Hordijk, P L, Aman, J & Bogaard, H J 2022, ' Epigenetic Modification of the von Willebrand Factor Promoter Drives Platelet Aggregation on the Pulmonary Endothelium in Chronic Thromboembolic Pulmonary Hypertension ', American Journal of Respiratory and Critical Care Medicine, vol. 205, no. 7, pp. 806-818 . https://doi.org/10.1164/rccm.202109-2075OC
American Journal of Respiratory and Critical Care Medicine, 205(7), 806-818. American Thoracic Society
Rationale: von Willebrand factor (vWF) mediates platelet adhesion during thrombosis. While chronic thromboembolic pulmonary hypertension (CTEPH) is associated with increased plasma levels of vWF, the role of this protein in CTEPH has remained enigmat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e382bcba5e7d072452cae1dd7c7f50
http://www.scopus.com/inward/record.url?scp=85128000994&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85128000994&partnerID=8YFLogxK
Autor:
Godefridus J. Peters, Masakazu Fukushima, Paul P. Eijk, Bauke Ylstra, Richard J. Honeywell, Kees Smid, Auke D. Adema, Nienke Losekoot, Henk-Jan Prins, Irene V. Bijnsdorp, Olaf H. Temmink
Trifluorothymidine (TFT) is part of the novel oral formulation TAS-102, which is currently evaluated in phase II studies. Drug resistance is an important limitation of cancer therapy. The aim of the present study was to induce resistance to TFT in H6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae2bf0ea06ae01c6fec69291c8b070d
https://doi.org/10.1158/1535-7163.c.6531774
https://doi.org/10.1158/1535-7163.c.6531774
Autor:
Godefridus J. Peters, Masakazu Fukushima, Paul P. Eijk, Bauke Ylstra, Richard J. Honeywell, Kees Smid, Auke D. Adema, Nienke Losekoot, Henk-Jan Prins, Irene V. Bijnsdorp, Olaf H. Temmink
Supplementary Data from Trifluorothymidine Resistance Is Associated with Decreased Thymidine Kinase and Equilibrative Nucleoside Transporter Expression or Increased Secretory Phospholipase A2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c33d9c0373858d6e8a91df2cdb7760b
https://doi.org/10.1158/1535-7163.22485105.v1
https://doi.org/10.1158/1535-7163.22485105.v1
Autor:
Danijela Koppers-Lalic, Michael Hackenberg, Irene V. Bijnsdorp, Monique A.J. van Eijndhoven, Payman Sadek, Daud Sie, Nicoletta Zini, Jaap M. Middeldorp, Bauke Ylstra, Renee X. de Menezes, Thomas Würdinger, Gerrit A. Meijer, D. Michiel Pegtel
Publikováno v:
Cell Reports, Vol 8, Iss 6, Pp 1649-1658 (2014)
Functional biomolecules, including small noncoding RNAs (ncRNAs), are released and transmitted between mammalian cells via extracellular vesicles (EVs), including endosome-derived exosomes. The small RNA composition in cells differs from exosomes, bu
Externí odkaz:
https://doaj.org/article/f776573975bc4c1da290c4277a668ad5
Large-Scale Urinary Proteome Dataset Across Tumor Types Reveals Candidate Biomarkers for Lung Cancer
Autor:
Irene V. Bijnsdorp, Connie R. Jimenez
Publikováno v:
EBioMedicine, Vol 30, Iss , Pp 5-6 (2018)
Externí odkaz:
https://doaj.org/article/c20c34630cea40bc99cf3acce19828dc
Autor:
Magda Wachalska, Danijela Koppers-Lalic, Monique van Eijndhoven, Michiel Pegtel, Albert A. Geldof, Andrea D. Lipinska, R. Jeroen van Moorselaar, Irene V. Bijnsdorp
Publikováno v:
Journal of Circulating Biomarkers, Vol 5 (2016)
Urine exosomes (extracellular vesicles; EVs) contain (micro)RNA (miRNA) and protein biomarkers that are useful for the non-invasive diagnosis of various urological diseases. However, the urinary Tamm-Horsfall protein (THP) complex, which forms at red
Externí odkaz:
https://doaj.org/article/8b57e6208c5f4aa0958d5a4682a46171