Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Irene Tsina"'
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 19:957-967
A precise and accurate HPLC method for the quantification of ketorolac in human plasma is described. Ketorolac and an added internal standard (a fluoro analog of ketorolac) are extracted from acidified plasma samples and the extract is further purifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8b3c65a7504a5841818e5fc08ecab9
https://doi.org/10.1080/10826079608001926
https://doi.org/10.1080/10826079608001926
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 675:119-129
A manual and an automated (Zymark PyTechnology robot) HPLC method for simultaneous determination of plasma mycophenolic acid (MPA) and its glucuronide conjugate (MPAG) are described here. Both methods are reproducible and accurate, and both are equiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd621e1ef90a35adeabd839e59b3eb5
https://doi.org/10.1016/0378-4347(95)00343-6
https://doi.org/10.1016/0378-4347(95)00343-6
Autor:
Suzanne K. Swan, Heather J. Johnson, Andrew J. Nicholls, Karen L. Heim-Duthoy, Thomas Tarnowski, Irene Tsina
Publikováno v:
Clinical pharmacology and therapeutics. 63(5)
Background The purpose of this study was to determine the effect of renal function on the elimination and disposition of mycophenolic acid and its glucuronide metabolite (MPAG) after oral administration of the pro-drug mycophenolate mofetil. In addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5f9e7d7ab04020e98fd5a9774f15a5
https://pubmed.ncbi.nlm.nih.gov/9630824
https://pubmed.ncbi.nlm.nih.gov/9630824
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 15(3)
An indirect and a direct HPLC method for the quantification of the (R) and (S) enantiomers of ketorolac are described here. The indirect method employs the chiral amine (+)-R-1-(1-naphthyl)ethylamine to form disastereomeric amides; separation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d061cf9aa2cb3714ad7dcbdf4f167b
https://pubmed.ncbi.nlm.nih.gov/8951702
https://pubmed.ncbi.nlm.nih.gov/8951702
Publikováno v:
Journal of chromatography. B, Biomedical applications. 681(2)
A method for the quantification of mycophenolate mofetil (MMF, CellCept) in plasma using solid-phase extraction and HPLC is described here. A solution of internal standard is added to a 0.5-ml plasma aliquot. The resulting sample is treated with wate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ae85c228fb03a2fc8b9fe75d45fabc
https://pubmed.ncbi.nlm.nih.gov/8811446
https://pubmed.ncbi.nlm.nih.gov/8811446
Autor:
Daniel Combs, Yuen Tam, Irene Tsina, Edward J. Mroszczak, Thomas Tarnowski, Aileen E. Boyd, Melvin Chaplin, Cynthia Rocha, Linval Depass, John A. Young
Publikováno v:
Journal of clinical pharmacology. 36(6)
It has been shown that the analgesic and cyclooxygenase inhibitor activity of ketorolac tromethamine (KT), which is marketed as the racemic mixture of (-)S and (+)R enantiomers, resides primarily with (-)S ketorolac and that the ulcerogenic activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3935bbb1dd77fae51b0b1540791f280a
https://pubmed.ncbi.nlm.nih.gov/8809637
https://pubmed.ncbi.nlm.nih.gov/8809637
Autor:
Eric J. Benjamin, Ian J. Massey, Robert Bergstrom, Ya-Yun T. Lin, Bruce A. Firestone, Irene Tsina, Marian Fass
Publikováno v:
Pharmaceutical Research. :120-125
Various diesters of 9-[(1,3-dihydroxy-2-propoxy)-methyl]guanine (DHPG) were screened in order to identify a derivative with improved oral absorption. The solubilities and dissolution rates decreased with increasing chain length and branching of the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa7f94413e6c9787f579e2dfd6bba6f
https://doi.org/10.1023/a:1016462801968
https://doi.org/10.1023/a:1016462801968
Publikováno v:
Journal - Association of Official Analytical Chemists. 65(3)
Oxfendazole (methyl 5-(phenylsulfinyl)-2-benzimidazole- carbamate) is a broad spectrum anthelmintic agent designed for use in food-producing animals. A simple radioimmunoassay (RIA) for determination of oxfendazole in plasma was modified for determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725b9bfba510049d7e0a231d62696a51
https://pubmed.ncbi.nlm.nih.gov/7096245
https://pubmed.ncbi.nlm.nih.gov/7096245