Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Irene Sizing"'
Autor:
Zhifang Li, Steven D. Miklasz, Joseph V. Bonventre, Takaharu Ichimura, Lourdes Pablo, Patricia Mccoon, Irene Sizing, Veronique Bailly, Paul D. Rennert, Leticia Tarilonte, Rachel Rennard
Publikováno v:
The Journal of Immunology. 177:4311-4321
The development of asthma and other atopic diseases is influenced by cytokines produced by Th2 effector T cells. How effector T cell responses are regulated once these cell populations are established remains unclear. The recently described T cell an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f95a903cdc514c0c9c7c41a9c43634
https://doi.org/10.4049/jimmunol.177.7.4311
https://doi.org/10.4049/jimmunol.177.7.4311
Autor:
Laura Runkell, Carole de Dios, Siti H. Masri, Federica M. Marelli-Berg, Rachel David, Irene Sizing, Arpita Datta, Martha J. James, Meleri Jones, Graham R. Foster, Giovanna Lombardi
Publikováno v:
The Journal of Immunology. 173:1663-1670
The type I IFN family includes 14 closely related antiviral cytokines that are produced in response to viral infections. They bind to a common receptor, and have qualitatively similar biological activities. The physiological relevance of this redunda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5272a871a6b8d37f6ece9c8712bd21fe
https://doi.org/10.4049/jimmunol.173.3.1663
https://doi.org/10.4049/jimmunol.173.3.1663
Autor:
Christopher D. Benjamin, Sarah A. Bixler, Kalpit Vora, Jürg Tschopp, Jeffrey Thompson, Christine Ambrose, Catherine Hession, Martin L. Scott, Jeffrey L. Browning, Irene Sizing, Kathy Strauch, Mohammad Zafari, Pascal Schneider, Fang Qian, Teresa G. Cachero, Colleen Mullen
Publikováno v:
Science. 293:2108-2111
B cell homeostasis has been shown to critically depend on BAFF, the B cell activation factor from the tumor necrosis factor (TNF) family. Although BAFF is already known to bind two receptors, BCMA and TACI, we have identified a third receptor for BAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c3f49fedd3f751eedb5fd6d3b5f79ec
https://doi.org/10.1126/science.1061965
https://doi.org/10.1126/science.1061965
Autor:
Irene Sizing, Jianliang Yang, Alexandra Delacour, Paul Rayhorn, Renee I. Shapiro, Zhong-Ying Liu, Kevin P. Williams, Frederick R. Taylor, Laure Gambardella, Linda C. Burkly, Christopher D. Benjamin, Yann Barrandon, Ellen Garber, Leona E. Ling, Li Chun Wang
Publikováno v:
Journal of Investigative Dermatology. 114:901-908
Members of the vertebrate hedgehog family (Sonic, Indian, and Desert) have been shown to be essential for the development of various organ systems, including neural, somite, limb, skeletal, and for male gonad morphogenesis. Sonic hedgehog and its cog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3ca6629a10064225a7205dba9b81d2
https://doi.org/10.1046/j.1523-1747.2000.00951.x
https://doi.org/10.1046/j.1523-1747.2000.00951.x
Autor:
Sarah Ryan, S.Y. Venyaminov, Christopher D. Benjamin, Mohammad Zafari, Philip Gotwals, Gloria Chi-Rosso, J Singh, Irene Sizing, R B Pepinsky, Victor Koteliansky
Publikováno v:
Biochemistry. 38:8280-8288
Recent structural and functional analyses of alpha integrin subunit I domains implicate a region in cation and ligand binding referred to as the metal ion-dependent adhesion site (MIDAS). Although the molecular interactions between Mn2+ and Mg2+ and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ce201c72a61c9d6b743bcc901e04fc
https://doi.org/10.1021/bi982860m
https://doi.org/10.1021/bi982860m
Autor:
Irene Sizing, Cedric S. Raine, Christopher D. Benjamin, Jeffrey L. Browning, Barbara Cannella
Publikováno v:
Journal of Neuroimmunology. 78:172-179
The cytokine lymphotoxin (LT) is known to exist in two forms, secreted LT α and a membrane-bound LT α / β complex. LT α shares the same receptor as tumor necrosis factor α and LT β is recognized by its receptor, LT β R. Since LT has been assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b060f0bd97604613f72cb28c37cda7d3
https://doi.org/10.1016/s0165-5728(97)00098-2
https://doi.org/10.1016/s0165-5728(97)00098-2
Autor:
Wenjie Chang, Lourdes Pablo, Steven D. Miklasz, Meghan E. Walsh, Zhifang Li, Max Dobles, Mohammad Zafari, Martin L. Scott, Rachel Rennard, Irene Sizing, Sambasiva P. Rao, Patricia Mccoon, Leticia Tarilonte, Kevin Godbout, Paul D. Rennert, Gerard R. Majeau, Veronique Bailly
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 178(4)
The TAPR locus containing the TIM gene family is implicated in the development of atopic inflammation in mouse, and TIM-1 allelic variation has been associated with the incidence of atopy in human patient populations. In this study, we show that mani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfd2d941d4504f931b811938ed89365
https://pubmed.ncbi.nlm.nih.gov/17277130
https://pubmed.ncbi.nlm.nih.gov/17277130
Autor:
Carlos Martínez-A, Irene Sizing, Sandra Rodriguez-Mascarenhas, Ángel Zaballos, Michael Leitges, Paul D. Rennert, Judit Kovac, Maria T. Diaz-Meco, Ricardo Villares, Jorge Moscat, Pilar Martín, Gabriel Márquez
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Asthma is a disease of chronic airway inflammation in which T helper (Th) 2 cells play a critical role. The molecular mechanisms controlling Th2 differentiation and function are of paramount importance in biology and immunology. PKCζ has been implic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6c55f29639c56f18f52efebec54837
https://hdl.handle.net/11858/00-001M-0000-0028-80D6-011858/00-001M-0000-0012-E895-6
https://hdl.handle.net/11858/00-001M-0000-0028-80D6-011858/00-001M-0000-0012-E895-6
Autor:
Cheryl Nickerson-Nutter, Irene Sizing, Jeffrey L. Browning, Stuart J. Perper, Apinya Ngam-ek, Jennifer L. Gommerman, Keith Giza
Publikováno v:
The Journal of clinical investigation. 112(5)
In studies using genetically deficient mice, a role for the lymphotoxin (LT) system in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) has remained controversial. Here, we have reassessed this conclusion by using a fusion protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70a1867fabee8c7a2d152477af9d343
https://pubmed.ncbi.nlm.nih.gov/12952924
https://pubmed.ncbi.nlm.nih.gov/12952924
Autor:
Beth Browning, Irene Sizing, Christine Ambrose, Yen-Ming Hsu, Aniela Jakubowski, Jeffrey Thompson, Matvey E. Lukashev, Christopher D. Benjamin, Timothy S. Zheng, Linda C. Burkly
Publikováno v:
Journal of cell science. 115(Pt 2)
Angiogenic regulators modulate endothelial cell functions, including proliferation, migration, secretion, and adhesion, through their action on endothelial cells or other cell types. TWEAK, a novel member of the tumor necrosis factor family, appears
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8efda7734fc2e924b40cb5c3f0dc3fc
https://pubmed.ncbi.nlm.nih.gov/11839778
https://pubmed.ncbi.nlm.nih.gov/11839778