Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Irene Silva, Soares"'
Autor:
Rafaella Oliveira dos Santos, Maria Geuziane Soares da Cruz, Stefanie Costa Pinto Lopes, Lucas Barbosa Oliveira, Paulo Afonso Nogueira, Emerson Silva Lima, Irene Silva Soares, Flora Satiko Kano, Andréa Teixeira de Carvalho, Fabio Trindade Maranhão Costa, Christian A. Ganoza, Marcus Vinicius Guimarães de Lacerda, Pritesh Lalwani
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The human immune response that controls Plasmodium infection in the liver and blood stages of the parasite life cycle is composed by both pro- and anti-inflammatory programs. Pro-inflammatory responses primarily mediated by IFN-γ controls the infect
Externí odkaz:
https://doaj.org/article/51cd823397684eab9ea8e35f12e949d3
Autor:
Irina Dobrescu, Tarsila Mendes de Camargo, Alba Marina Gimenez, Oscar Murillo, Kelly Nazaré da Silva Amorim, Claudio Romero Farias Marinho, Irene Silva Soares, Silvia Beatriz Boscardin, Daniel Youssef Bargieri
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The lack of continuous in vitro cultures has been an obstacle delaying pre-clinical testing of Plasmodium vivax vaccine formulations based on known antigens. In this study, we generated a model to test available formulations based on the P. vivax MSP
Externí odkaz:
https://doaj.org/article/1f5af45c58e64fc5a7eb1fadd50b4107
Autor:
Flora Satiko Kano, Aracele Maria de Souza, Leticia de Menezes Torres, Marcelo Azevedo Costa, Flávia Alessandra Souza-Silva, Bruno Antônio Marinho Sanchez, Cor Jesus Fernandes Fontes, Irene Silva Soares, Cristiana Ferreira Alves de Brito, Luzia Helena Carvalho, Tais Nobrega Sousa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Malaria has provided a major selective pressure and has modulated the genetic diversity of the human genome. The variants of the Duffy Antigen/Receptor for Chemokines (DARC) gene have probably been selected by malaria parasites, particularly
Externí odkaz:
https://doaj.org/article/33cfd9ed40a8459583acd20767c13c78
Autor:
Renan Antonialli, Fernando Bandeira Sulczewski, Kelly Nazaré da Silva Amorim, Bianca da Silva Almeida, Natália Soares Ferreira, Márcio Massao Yamamoto, Irene Silva Soares, Luís Carlos de Souza Ferreira, Daniela Santoro Rosa, Silvia Beatriz Boscardin
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Dendritic cells (DCs) are antigen-presenting cells essential for the induction of adaptive immune responses. Their unprecedented ability to present antigens to T cells has made them excellent targets for vaccine development. In the last years, a new
Externí odkaz:
https://doaj.org/article/298d952be12d498ea9148b05050f16b7
Autor:
Maria Marta Figueiredo, Pedro Augusto Carvalho Costa, Suelen Queiroz Diniz, Priscilla Miranda Henriques, Flora Satiko Kano, Mauro Sugiro Tada, Dhelio Batista Pereira, Irene Silva Soares, Olindo Assis Martins-Filho, Dragana Jankovic, Ricardo Tostes Gazzinelli, Lis Ribeiro do Valle Antonelli
Publikováno v:
PLoS Pathogens, Vol 13, Iss 7, p e1006484 (2017)
Although the importance of humoral immunity to malaria has been established, factors that control antibody production are poorly understood. Follicular helper T cells (Tfh cells) are pivotal for generating high-affinity, long-lived antibody responses
Externí odkaz:
https://doaj.org/article/aec43ae40f6443a09205c6b3d404e4ea
Autor:
Lilian Lacerda Bueno, Francisco Pereira Lobo, Cristiane Guimarães Morais, Luíza Carvalho Mourão, Ricardo Andrez Machado de Ávila, Irene Silva Soares, Cor Jesus Fontes, Marcus Vinícius Lacerda, Carlos Chavez Olórtegui, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara, Erika Martins Braga
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21289 (2011)
Apical membrane antigen 1 (AMA-1) is considered to be a major candidate antigen for a malaria vaccine. Previous immunoepidemiological studies of naturally acquired immunity to Plasmodium vivax AMA-1 (PvAMA-1) have shown a higher prevalence of specifi
Externí odkaz:
https://doaj.org/article/e6f46393aa79495ba01882633bdb1e69
Autor:
Lilian Lacerda Bueno, Cristiane Guimarães Morais, Fernanda Fortes Araújo, Juliana Assis Silva Gomes, Rodrigo Corrêa-Oliveira, Irene Silva Soares, Marcus Vinícius Lacerda, Ricardo Toshio Fujiwara, Erika Martins Braga
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9623 (2010)
Circulation CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) have been associated with the delicate balancing between control of overwhelming acute malaria infection and prevention of immune pathology due to disproportionate inflammatory responses to
Externí odkaz:
https://doaj.org/article/61079170d7a5421f8f7b6297a6fb9e19
Autor:
Renan Antonialli, Fernando Bandeira Sulczewski, Kelly Nazaré da Silva Amorim, Bianca da Silva Almeida, Natália Soares Ferreira, Márcio Massao Yamamoto, Irene Silva Soares, Luís Carlos de Souza Ferreira, Daniela Santoro Rosa, Silvia Beatriz Boscardin
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2017)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2017)
Dendritic cells (DCs) are antigen-presenting cells essential for the induction of adaptive immune responses. Their unprecedented ability to present antigens to T cells has made them excellent targets for vaccine development. In the last years, a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d21a9acfd8540d4ac4336d6cee8ca6
Autor:
Melissa Cavalheiro, Tourino, Edson Mendes, de Oliveira, Luziane Potrich, Bellé, Franciele Hinterholz, Knebel, Renata Chaves, Albuquerque, Felipe Augusto, Dörr, Sabrina Sayori, Okada, Silene, Migliorini, Irene Silva, Soares, Ana, Campa
Publikováno v:
Cell biochemistry and function. 31(5)
Indoleamine 2,3-dioxygenase (IDO) is an interferon-γ (IFN-γ)-induced tryptophan-degrading enzyme, producing kynurenine (KYN) that participates in the mechanism of tumor immune tolerance. Thus, IDO inhibition has been considered a strategy for antic
Autor:
Luiza Carvalho, Mourão, Cristiane Guimarães, Morais, Lilian Lacerda, Bueno, Maria Carolina, Jimenez, Irene Silva, Soares, Cor Jesus, Fontes, Marcus Vinícius, Guimarães Lacerda, Marcos Silva, Xavier, John W, Barnwell, Mary R, Galinski, Erika Martins, Braga
Publikováno v:
Microbes and infection. 14(9)
An important step when designing a vaccine is identifying the antigens that function as targets of naturally acquired antibodies. We investigated specific antibody responses against two Plasmodium vivax vaccine candidates, PvMSP-1₁₉ and PvMSP-3α