Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Irene Sansano"'
Autor:
Jose Pérez-Cano, Irene Sansano Valero, David Anglada-Rotger, Oscar Pina, Philippe Salembier, Ferran Marques
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28463- (2024)
The detection of tumoural cells from whole slide images is an essential task in medical diagnosis and research. In this article, we propose and analyse a novel approach that combines computer vision-based models with graph neural networks to improve
Externí odkaz:
https://doaj.org/article/3eac85977f404a7caa72dfc48afb752c
Autor:
Esther Conde, MD, PhD, Susana Hernandez, PhD, Jose Luis Rodriguez Carrillo, MD, Rebeca Martinez, APT, Marta Alonso, APT, Daniel Curto, MD, Beatriz Jimenez, MD, Alejandra Caminoa, MD, PhD, Amparo Benito, MD, Pilar Garrido, MD, PhD, Sergi Clave, PhD, Edurne Arriola, MD, PhD, Isabel Esteban-Rodriguez, MD, PhD, Javier De Castro, MD, PhD, Irene Sansano, MD, Enriqueta Felip, MD, PhD, Federico Rojo, MD, PhD, Manuel Dómine, MD, PhD, Ihab Abdulkader, MD, PhD, Jorge Garcia-Gonzalez, MD, Cristina Teixido, PhD, Noemi Reguart, MD, PhD, Desamparados Compañ, MD, PhD, Amelia Insa, MD, Nuria Mancheño, MD, PhD, Sarai Palanca, MD, PhD, Oscar Juan-Vidal, MD, PhD, Nuria Baixeras, MD, Ernest Nadal, MD, PhD, Maria Cebollero, MD, Antonio Calles, MD, Paloma Martin, MD, PhD, Clara Salas, MD, PhD, Mariano Provencio, MD, PhD, Ignacio Aranda, MD, PhD, Bartomeu Massuti, MD, Laura Lopez-Vilaro, MD, Margarita Majem, MD, PhD, Luis Paz-Ares, MD, PhD, Fernando Lopez-Rios, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 4, Pp 100653- (2024)
Introduction: RET inhibitors with impressive overall response rates are now available for patients with NSCLC, yet the identification of RET fusions remains a difficult challenge. Most guidelines encourage the upfront use of next-generation sequencin
Externí odkaz:
https://doaj.org/article/a3e58ca9d39948fda3972ff1d75a8f34
Autor:
Robert Camp, Maxwell L. Smith, Brandon T. Larsen, Anja C. Roden, Carol Farver, Andre L. Moreira, Richard Attanoos, Raghavendra Pillappa, Irene Sansano, Alexandre Todorovic Fabro, Robert J. Homer
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Current interstitial lung disease (ILD) diagnostic guidelines assess criteria across clinical, radiologic and pathologic domains. Significant interobserver variation in histopathologic evaluation has previously been shown but the
Externí odkaz:
https://doaj.org/article/59d0209d00e74ffe976371282aa60c7d
Autor:
Judith Grau-Expósito, Nerea Sánchez-Gaona, Núria Massana, Marina Suppi, Antonio Astorga-Gamaza, David Perea, Joel Rosado, Anna Falcó, Cristina Kirkegaard, Ariadna Torrella, Bibiana Planas, Jordi Navarro, Paula Suanzes, Daniel Álvarez-Sierra, Alfonso Ayora, Irene Sansano, Juliana Esperalba, Cristina Andrés, Andrés Antón, Santiago Ramón y Cajal, Benito Almirante, Ricardo Pujol-Borrell, Vicenç Falcó, Joaquín Burgos, María J. Buzón, Meritxell Genescà
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Lung resident memory T (TRM) cells are important for protection from viral infection in the lungs. Here the authors use paired lung biopsy material and blood to characterize T cell responses in patients with COVID-19 over time and find persistence of
Externí odkaz:
https://doaj.org/article/5dc22db21e084436a0fa9fda65b04bc7
Autor:
Joan Frigola, Alejandro Navarro, Caterina Carbonell, Ana Callejo, Patricia Iranzo, Susana Cedrés, Alex Martinez‐Marti, Nuria Pardo, Nadia Saoudi‐Gonzalez, Debora Martinez, Jose Jimenez, Irene Sansano, Francesco M. Mancuso, Paolo Nuciforo, Luis M. Montuenga, Montse Sánchez‐Cespedes, Aleix Prat, Ana Vivancos, Enriqueta Felip, Ramon Amat
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 887-900 (2021)
Immunotherapy has transformed advanced non‐small cell lung cancer (NSCLC) treatment strategies and has led to unprecedented long‐lasting responses in some patients. However, the molecular determinants driving these long‐term responses remain el
Externí odkaz:
https://doaj.org/article/5d71f89668ed4454856fe4896f4856ea
Autor:
Silvia Sánchez-Díez, María Jesús Cruz, Miquel de Homdedeu, Iñigo Ojanguren, Christian Romero-Mesones, Irene Sansano, Xavier Muñoz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2884 (2023)
Bird-related hypersensitivity pneumonitis (BRHP) is an interstitial lung disease induced by avian proteins. The immunopathological pathways involved in the disease are still unknown. This study assesses the cellular immune response and the cytokine p
Externí odkaz:
https://doaj.org/article/6132e4a86f6541c0aac274ffa4b931cc
Autor:
Cristina Martín Rodríguez, Carolina E. Haro, Luisa S. Silva Alcoser, Irene Sansano Valero, Marcos Pérez-Carrasco
Publikováno v:
Medicina Clínica Práctica, Vol 4, Iss , Pp 100305- (2021)
Externí odkaz:
https://doaj.org/article/8d3c0f9d89cb41feaf64560b74238bd5
Autor:
Marta Sesé, Rosa Somoza, Inmaculada Maestu, Maria Martín Ureste, Alfredo Sanchez, Juan Felipe Cordoba, Irene Sansano, Griselda Venturas, Santiago Ramón y Cajal, Javier Hernández-Losa
Publikováno v:
Oncology and Therapy, Vol 7, Iss 2, Pp 131-139 (2019)
Abstract Introduction Precision medicine has revolutionized the understanding and treatment of cancer by identifying subsets of patients who are amenable to specific treatments according to their molecular characteristics, as exemplified by epidermal
Externí odkaz:
https://doaj.org/article/c772a29e300a49fca60185f306821587
Autor:
Trond Aasen, Irene Sansano, Maria Ángeles Montero, Cleofé Romagosa, Jordi Temprana-Salvador, Alexandre Martínez-Marti, Teresa Moliné, Javier Hernández-Losa, Santiago Ramón y Cajal
Publikováno v:
Cancers, Vol 11, Iss 3, p 320 (2019)
Direct intercellular communication, mediated by gap junctions formed by the connexin transmembrane protein family, is frequently dysregulated in cancer. Connexins have been described as tumour suppressors, but emerging evidence suggests that they can
Externí odkaz:
https://doaj.org/article/9a7150223f9241188cc15e53a45acc8a
Autor:
Susana Cedrés, Santiago Ponce-Aix, Jon Zugazagoitia, Irene Sansano, Ana Enguita, Alejandro Navarro-Mendivil, Alex Martinez-Marti, Pablo Martinez, Enriqueta Felip
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121071 (2015)
BackgroundThe increasing incidence and poor outcome associated with MPM requires finding effective treatment for this disease. PD1/PD-L1 pathway plays a central role in tumor immune evasion and appears to be predictive and prognostic marker. PD-L1 is
Externí odkaz:
https://doaj.org/article/94efa7688f654929aaaa25a78d985aa6