Brief Report: Astrogliosis Promotes Functional Recovery of Completely Transected Spinal Cord Following Transplantation of hESC-Derived Oligodendrocyte and Motoneuron Progenitors

Autor: Slaven Erceg, Dunja Lukovic, Victoria Moreno-Manzano, Irene Sanchez-Vera, Miodrag Stojkovic, Lourdes Valdés-Sánchez, Shomi S. Bhattacharya

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
STEM CELLS
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)

Spinal cord injury results in neural loss and consequently motor and sensory impairment below the injury. Reactive astrocytes contribute to formation of glial scar, thus impeding axonal regeneration, through secretion of extracellular matrix molecule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e59c018852b9d13a816e8dd90593bb2
https://doi.org/10.1002/stem.1562

Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population

Autor: Valeria, Chichagova, Irene, Sanchez-Vera, Lyle, Armstrong, David, Steel, Majlinda, Lako

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1353

Human induced pluripotent stem cells (hiPSCs) provide a platform for studying human disease in vitro, increase our understanding of human embryonic development, and provide clinically relevant cell types for transplantation, drug testing, and toxicol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e82627c8f4e705cf01462b2cdee6aa9
https://pubmed.ncbi.nlm.nih.gov/25697416

Genetic Impairment of Frontocortical Endocannabinoid Degradation and High Alcohol Preference

Autor: Irene Sanchez-Vera, Anita C. Hansson, Markus Heilig, Wolfgang H. Sommer, Francisco Javier Bermúdez-Silva, Petri Hyytiä, Fernando Rodríguez de Fonseca, Roberto Rimondini, Hanna Malinen, George Kunos

Publikováno v: Neuropsychopharmacology. 32:117-126

Endocannabinoid signaling has recently been implicated in ethanol-seeking behavior. We analyzed the expression of endocannabinoid-related genes in key brain regions of reward and dependence, and compared them between the alcohol-preferring AA (Alko A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f4a61050e8610735cb4cd16be484941
https://doi.org/10.1038/sj.npp.1301034

Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation and Brain Damage

Autor: Maya Pascual-Lucas, Silvia Alfonso-Loeches, Ana M. Blanco, Irene Sanchez-Vera, Consuelo Guerri

Publikováno v: JOURNAL OF NEUROSCIENCE
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

Toll-like receptors play an important role in the innate immune response, although emerging evidence indicates their role in brain injury and neurodegeneration. Alcohol abuse induces brain damage and can sometimes lead to neurodegeneration. We recent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218e1783d042dbb8a4abb751d8bd42fd
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2762

Spanish real-world experience with fingolimod in relapsing-remitting multiple sclerosis patients: MS NEXT study.

Autor: Francisco Barrero, Javier Mallada-Frechin, María Luisa Martínez-Ginés, María Eugenia Marzo, Virginia Meca-Lallana, Guillermo Izquierdo, José Ramón Ara, Celia Oreja-Guevara, José Meca-Lallana, Lucía Forero, Irene Sánchez-Vera, María José Moreno, in representation of the MS NEXT study investigators

Publikováno v: PLoS ONE, Vol 15, Iss 4, p e0230846 (2020)

PurposeThe objective of this study was to characterize the demographic and clinical profile of RRMS patients receiving fingolimod in Spain, and to evaluate drug effectiveness and safety in clinical practice.MethodsThis observational, retrospective, m

Externí odkaz: https://doaj.org/article/35e01650c3644a1095a86b39b5d34dd7