Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Irene Ramos-Alvarez"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7286 (2024)
Whether the long-term treatment of patients with proton pump inhibitors (PPIs) with different diseases [GERD, Zollinger–Ellison syndrome (ZES), etc.] can result in vitamin B12 (VB12) deficiency is controversial. In this study, in 175 patients under
Externí odkaz:
https://doaj.org/article/524dbf08fe334a50930bb98bb35ac478
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: The actin regulatory protein, cofilin plays a key signaling role in many cells for numerous cellular responses including in proliferation, development, motility, migration, secretion and growth. In the pancreas it is important in islet
Externí odkaz:
https://doaj.org/article/67450737965b457a8df6aee1970c1c86
Publikováno v:
Biology, Vol 12, Iss 7, p 957 (2023)
The ErbB RTKs (EGFR, HER2, HER3, and HER4) have been well-studied in cancer. EGFR, HER2, and HER3 stimulate cancer proliferation, principally by activating the phosphatidylinositol-3-kinase and extracellular signal-regulated kinase (ERK) pathways, re
Externí odkaz:
https://doaj.org/article/bb4059854e944339987df6802f5c8166
Autor:
Terry W. Moody, Lingaku Lee, Irene Ramos-Alvarez, Tatiana Iordanskaia, Samuel A. Mantey, Robert T. Jensen
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
G-protein-coupled receptors (GPCRs) are increasingly being considered as possible therapeutic targets in cancers. Activation of GPCR on tumors can have prominent growth effects, and GPCRs are frequently over-/ectopically expressed on tumors and thus
Externí odkaz:
https://doaj.org/article/9dc83171ba4748c3a0890f861c85137d
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Neuropeptide G protein-coupled receptors (GPCRs) are overexpressed on numerous cancer cells. In a number of tumors, such as small cell lung cancer (SCLC), bombesin (BB) like peptides and neurotensin (NTS) function as autocrine growth factors whereby
Externí odkaz:
https://doaj.org/article/ca3a76d176184c8f8fec7790f01850f1
Autor:
Terry W. Moody, Nicole Tashakkori, Samuel A. Mantey, Paola Moreno, Irene Ramos-Alvarez, Marcello Leopoldo, Robert T. Jensen
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
While peptide antagonists for the gastrin-releasing peptide receptor (BB2R), neuromedin B receptor (BB1R), and bombesin (BB) receptor subtype-3 (BRS-3) exist, there is a need to develop non-peptide small molecule inhibitors for all three BBR. The BB
Externí odkaz:
https://doaj.org/article/89b118da576445d1a02a4cc4cbcd7c38
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5128 (2019)
The use of proton pump inhibitors (PPIs) over the last 30 years has rapidly increased both in the United States and worldwide. PPIs are not only very widely used both for approved indications (peptic ulcer disease, gastroesophageal reflux disease (GE
Externí odkaz:
https://doaj.org/article/d7e2de6538d148a2b37e8dc4ccd18118
Publikováno v:
Cancers
Volume 15
Issue 5
Pages: 1377
Volume 15
Issue 5
Pages: 1377
Analysis of the efficacy/pharmacology of long-term/lifetime medical treatment of acid hypersecretion in a large cohort of ZES patients in a prospective study. This study includes the results from all 303 patients with established ZES who were prospec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374120cfb937ef42ddfeb9605a9218b4
Publikováno v:
J Pharmacol Exp Ther
Allosteric ligands of various G-protein–coupled receptors are being increasingly described and are providing important advances in the development of ligands with novel selectivity and efficacy. These unusual properties allow expanded opportunities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755b92f03e7447d997d5c45388daefd9
https://europepmc.org/articles/PMC9341266/
https://europepmc.org/articles/PMC9341266/
Publikováno v:
Cancer Research. 83:3071-3071
Pituitary adenylate cyclase activating polypeptide [PACAP] is a 27 amino acid peptide which stimulates the growth of numerous cancers including non-small cell lung cancer (NSCLC). PACAP binds with high affinity to the type B G protein-coupled recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10e49fa32d5b5313ab81d58aaec96c7d
https://doi.org/10.1158/1538-7445.am2023-3071
https://doi.org/10.1158/1538-7445.am2023-3071