Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Irene R. Kieba"'
Autor:
Irene R. Kieba, Edward T. Lally, Patrik Nygren, Angela C. Brown, Anuradha Dhingra, Kathleen Boesze-Battaglia, Nataliya Balashova
Publikováno v:
Cellular microbiology. 21(3)
Repeats-in-toxin leukotoxin (LtxA) produced by the oral bacterium Aggregatibacter actinomycetemcomitans kills human leukocytes in a lymphocyte function-associated antigen 1 (LFA-1, integrin α(L)/β(2))-dependent manner, although the mechanism for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e719721d7abdc16275fa9e2be4bc23
https://pubmed.ncbi.nlm.nih.gov/30329215
https://pubmed.ncbi.nlm.nih.gov/30329215
Publikováno v:
Journal of periodontology. 67
Actinobacillus actinomycetemcomitans has been implicated as a causative organism in early-onset periodontitis. The mechanisms by which A. actinomycetemcomitans is pathogenic are not known, but the organism produces several potential virulence factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0925718c88c99942df94f5811a6323
https://pubmed.ncbi.nlm.nih.gov/29539844
https://pubmed.ncbi.nlm.nih.gov/29539844
Aggregatibacter actinomycetemcomitans leukotoxin cytotoxicity occurs through bilayer destabilization
Autor:
Raquel F. Epand, Lazaros Kakalis, Yurong Du, Edward T. Lally, Frank P. Stefano, Kathleen Boesze-Battaglia, Philip L. Yeagle, Richard M. Epand, Angela C. Brown, Irene R. Kieba
Publikováno v:
Cellular Microbiology. 14:869-881
The Gram-negative bacterium, Aggregatibacter actinomycetemcomitans, is a common inhabitant of the human upper aerodigestive tract. The organism produces an RTX (Repeats in ToXin) toxin (LtxA) that kills human white blood cells. LtxA is believed to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7cfe25930412af8817cf45237e49b0e
https://doi.org/10.1111/j.1462-5822.2012.01762.x
https://doi.org/10.1111/j.1462-5822.2012.01762.x
Autor:
Irene R. Kieba, Noboru Yamaguchi, Edward T. Lally, Bruce J. Shenker, Pamela S. Howard, Jon Korostoff
Publikováno v:
Cellular Microbiology. 3:811-823
Subnanomolar concentrations (3 x 10(-10) M) of Actinobacillus actinomycetemcomitans leukotoxin (Ltx) trigger apoptosis of JY cells, as shown by a decrease in mitochondrial transmembrane potential (DeltaPsim), hyperproduction of reactive oxygen specie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d418c1d2f5628ccc251643b1713d89d
https://doi.org/10.1046/j.1462-5822.2001.00161.x
https://doi.org/10.1046/j.1462-5822.2001.00161.x
Autor:
Paul C. Billings, Irene R. Kieba, Edward T. Lally, Harry Rozmiarek, Bruce J. Shenker, Jon Korostoff, Noboru Yamaguchi, Tai Liang Guo, Jian Fei Wang
Publikováno v:
Microbial Pathogenesis. 25:317-331
Pasteurella haemolyticaleukotoxin (LKT) is a member of the RTX family of pore-forming toxins that kill bovine immune cells. Several studies have suggested that RTX toxins kill target cells by the induction of apoptosis. In the present study, BL3 bovi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41104b5d39fe59113655581f2c59ef77
https://doi.org/10.1006/mpat.1998.0236
https://doi.org/10.1006/mpat.1998.0236
Autor:
Jon Korostoff, Edward T. Lally, Joel Rosenbloom, Martyn K. Robinson, Cecelia L. Green, Bruce J. Shenker, Susan Ortlepp, Jian Fei Wang, Paul C. Billings, Irene R. Kieba, Atsushi Sato
Publikováno v:
Journal of Biological Chemistry. 272:30463-30469
Actinobacillus actinomycetemcomitans leukotoxin and Escherichia coli alpha-hemolysin are RTX toxins that kill human immune cells. We have obtained a monoclonal antibody (295) to a cell surface molecule present on toxin-sensitive HL60 cells that can i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc75a29f0a8791e6da4a14b16138b2da
https://doi.org/10.1074/jbc.272.48.30463
https://doi.org/10.1074/jbc.272.48.30463
Aggregatibacter actinomycetemcomitans leukotoxin cytotoxicity occurs through bilayer destabilization
Autor:
Angela C, Brown, Kathleen, Boesze-Battaglia, Yurong, Du, Frank P, Stefano, Irene R, Kieba, Raquel F, Epand, Lazaros, Kakalis, Philip L, Yeagle, Richard M, Epand, Edward T, Lally
Publikováno v:
Cellular microbiology. 14(6)
The Gram-negative bacterium, Aggregatibacter actinomycetemcomitans, is a common inhabitant of the human upper aerodigestive tract. The organism produces an RTX (Repeats in ToXin) toxin (LtxA) that kills human white blood cells. LtxA is believed to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a764b2fd24366f89ebe11fa148a2566f
https://pubmed.ncbi.nlm.nih.gov/22309134
https://pubmed.ncbi.nlm.nih.gov/22309134
Publikováno v:
Journal of Biological Chemistry. 269:31289-31295
Although extensive amino acid homology exists among the various Repeats in ToXin (RTX) family of bacterial cytolysins, the cellular and species specificities remain unique for individual toxins (i.e. Actinobacillus actinomycetemcomitans leukotoxin (L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a123e27e06b4697e257721820f79b65
https://doi.org/10.1016/s0021-9258(18)47421-2
https://doi.org/10.1016/s0021-9258(18)47421-2
Autor:
Kathleen Boesze-Battaglia, Angela C. Brown, Edward T. Lally, David W. Speicher, Hsin-Yao Tang, Karen P. Fong, Irene R. Kieba
Aggregatibacter actinomycetemcomitans, a common inhabitant of the human upper aerodigestive tract, produces a repeat in toxin (RTX), leukotoxin (LtxA). The LtxA is transcribed as a 114-kDa inactive protoxin with activation being achieved by attachmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6957dcef56cfc95378e7d252d1e27b36
https://europepmc.org/articles/PMC3404814/
https://europepmc.org/articles/PMC3404814/
Publikováno v:
Journal of Periodontal Research. 28:487-490
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7949d4a293a81e72e17ea9f23c50a318
https://doi.org/10.1111/j.1600-0765.1993.tb02109.x
https://doi.org/10.1111/j.1600-0765.1993.tb02109.x