Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Irene Pradas"'
Autor:
Natalia Mota-Martorell, Mariona Jove, Irene Pradas, Isabel Sanchez, José Gómez, Alba Naudi, Gustavo Barja, Reinald Pamplona
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101539- (2020)
Mitochondrial reactive oxygen species (ROS) production, specifically at complex I (Cx I), has been widely suggested to be one of the determinants of species longevity. The present study follows a comparative approach to analyse complex I in heart tis
Externí odkaz:
https://doaj.org/article/f8e4d88e746f46d3885516e7d0b8015d
Autor:
Mariona Jové, Irene Pradas, Natalia Mota-Martorell, Rosanna Cabré, Victoria Ayala, Isidre Ferrer, Reinald Pamplona
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Human brain evolution toward complexity has been achieved with increasing energy supply as the main adaptation in brain metabolism. Energy metabolism, like other biochemical reactions in aerobic cells, is under enzymatic control and strictly regulate
Externí odkaz:
https://doaj.org/article/e8b834370b12414a8b30a10a01a61d16
Publikováno v:
Redox Biology, Vol 23, Iss , Pp - (2019)
The human brain is a target of the aging process like other cell systems of the human body. Specific regions of the human brain exhibit differential vulnerabilities to the aging process. Yet the underlying mechanisms that sustain the preservation or
Externí odkaz:
https://doaj.org/article/6509585f81df43069420651459b69d52
Autor:
Mariona Jové, Natàlia Mota-Martorell, Irene Pradas, Meritxell Martín-Gari, Victoria Ayala, Reinald Pamplona
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1132 (2020)
The nonenzymatic adduction of malondialdehyde (MDA) to the protein amino groups leads to the formation of malondialdehyde-lysine (MDALys). The degree of unsaturation of biological membranes and the intracellular oxidative conditions are the main fact
Externí odkaz:
https://doaj.org/article/f4cf08173e8c42548b41a1953a8568e0
Autor:
Mariona Jové, Natàlia Mota-Martorell, Irene Pradas, José Daniel Galo-Licona, Meritxell Martín-Gari, Èlia Obis, Joaquim Sol, Reinald Pamplona
Publikováno v:
Molecules, Vol 25, Iss 18, p 4343 (2020)
Lipids were determinants in the appearance and evolution of life. Recent studies disclose the existence of a link between lipids and animal longevity. Findings from both comparative studies and genetics and nutritional interventions in invertebrates,
Externí odkaz:
https://doaj.org/article/69339fdf4c9c406a96063fa3ba0f1675
Autor:
Irene Pradas, Kevin Huynh, Rosanna Cabré, Victòria Ayala, Peter J. Meikle, Mariona Jové, Reinald Pamplona
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
In biological systems lipids generate membranes and have a key role in cell signaling and energy storage. Therefore, there is a wide diversity of molecular lipid expressed at the compositional level in cell membranes and organelles, as well as in tis
Externí odkaz:
https://doaj.org/article/795716c77a874554bf6bf18a58a61450
Autor:
Joaquim Sol, Èlia Obis, Natalia Mota‐Martorell, Irene Pradas, Jose Daniel Galo‐Licona, Meritxell Martin‐Garí, Anna Fernández‐Bernal, Marta Ortega‐Bravo, Jordi Mayneris‐Perxachs, Consuelo Borrás, José Viña, Mónica de la Fuente, Ianire Mate, Carles Biarnes, Salvador Pedraza, Joan C. Vilanova, Ramon Brugada, Rafel Ramos, Joaquin Serena, Lluís Ramió‐Torrentà, Víctor Pineda, Pepus Daunis‐I‐Estadella, Santiago Thió‐Henestrosa, Jordi Barretina, Josep Garre‐Olmo, Manuel Portero‐Otin, José Manuel Fernández‐Real, Josep Puig, Mariona Jové, Reinald Pamplona
Aging biology entails a cell/tissue deregulated metabolism that affects all levels of biological organization. Therefore, the application of “omic” techniques that are closer to phenotype, such as metabolomics, to the study of the aging process s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f145eb39399ceb59fcac84f78de70b97
https://repositori.udl.cat/handle/10459.1/463450
https://repositori.udl.cat/handle/10459.1/463450
Autor:
Sònia Gatius, Mariona Jove, Cristina Megino-Luque, Manel Albertí-Valls, Andree Yeramian, Nuria Bonifaci, Miquel Piñol, Maria Santacana, Irene Pradas, David Llobet-Navas, Reinald Pamplona, Xavier Matías-Guiu, Núria Eritja
Publikováno v:
Cancers; Volume 14; Issue 12; Pages: 2842
Metabolomic profiling analysis has the potential to highlight new molecules and cellular pathways that may serve as potential therapeutic targets for disease treatment. In this study, we used an LC-MS/MS platform to define, for the first time, the sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c203d989e3dcc86de3239e0e4085fc0
Autor:
Irene Pradas, Mariona Jové, Kevin Huynh, Marta Ingles, Consuelo Borras, Natalia Mota-Martorell, Jose Daniel Galo-Licona, Josep Puig, Jose Viña, Peter J Meikle, Reinald Pamplona
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Universitad de Lleida
A species-specific lipidome profile is an inherent feature linked to longevity in the animal kingdom. However, there is a lack of lipidomic studies on human longevity. Here, we use mass spectrometry-based lipidomics to detect and quantify 151 sphingo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cfaf1c3970c557092e91c974af111c
https://hdl.handle.net/10459.1/83646
https://hdl.handle.net/10459.1/83646
Autor:
Reinald Pamplona Gras, Irene Pradas Barriga, Alba Naudí i Farré, Mariona Jové Font, Natàlia Mota Martorell
Publikováno v:
Revista Española de Geriatría y Gerontología. 54:88-93
Introduccion. Entre los principales componentes lipidicos de las membranas celulares se encuentran los glicerofosfolipidos (GFL), que se sintetizan en una via de novo a partir del diacilglicerol (DAG). El perfil lipidico es una caracteristica optimiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f38c7ebd812ac55e87a41dc1507ae96e
https://doi.org/10.1016/j.regg.2018.05.006
https://doi.org/10.1016/j.regg.2018.05.006