Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Irene Moreno-Candilejo"'
Autor:
Juanita S. Lopez, Nina Tunariu, Johann S. de Bono, Udai Banerji, Anna R. Minchom, Jonathan Ratoff, Joo Ern Ang, Malaka Ameratunga, Miriam Estevez Timon, Dan Bar, Andra Curcean, Mariana Scaranti, Irene Moreno Candilejo, Crescens Tiu, Angelika Terbuch
Figure S1A. Correlation of patterns of DILD as per ATS/ERS classification and clinical severity. Figure S1B. A higher RMH DILD score predicts for increasing clinical severity of DILD as per CTCAE grading.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5852b69e6537fc2d94399f95d2795549
https://doi.org/10.1158/1078-0432.22475027
https://doi.org/10.1158/1078-0432.22475027
Autor:
Juanita S. Lopez, Nina Tunariu, Johann S. de Bono, Udai Banerji, Anna R. Minchom, Jonathan Ratoff, Joo Ern Ang, Malaka Ameratunga, Miriam Estevez Timon, Dan Bar, Andra Curcean, Mariana Scaranti, Irene Moreno Candilejo, Crescens Tiu, Angelika Terbuch
Figure S2. Continuation of IMP following radiological detection of asymptomatic DILD resulting in clinical deterioration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629d42fa47b66b3f5e57f678ae928b37
https://doi.org/10.1158/1078-0432.22475024.v1
https://doi.org/10.1158/1078-0432.22475024.v1
Autor:
Juanita S. Lopez, Nina Tunariu, Johann S. de Bono, Udai Banerji, Anna R. Minchom, Jonathan Ratoff, Joo Ern Ang, Malaka Ameratunga, Miriam Estevez Timon, Dan Bar, Andra Curcean, Mariana Scaranti, Irene Moreno Candilejo, Crescens Tiu, Angelika Terbuch
Table S1. Frequency of DILD as per category
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7591779790247bf34ccfe47cc3e0371f
https://doi.org/10.1158/1078-0432.22475018
https://doi.org/10.1158/1078-0432.22475018
Autor:
Juanita S. Lopez, Nina Tunariu, Johann S. de Bono, Udai Banerji, Anna R. Minchom, Jonathan Ratoff, Joo Ern Ang, Malaka Ameratunga, Miriam Estevez Timon, Dan Bar, Andra Curcean, Mariana Scaranti, Irene Moreno Candilejo, Crescens Tiu, Angelika Terbuch
Purpose:Drug-induced interstitial lung disease (DILD) is a rare, but potentially fatal toxicity. Clinical and radiological features of DILD in the early experimental setting are poorly described.Patients and Methods:A total of 2,499 consecutive patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de593b8cd345d5233271cdb33caa91d
https://doi.org/10.1158/1078-0432.c.6528971
https://doi.org/10.1158/1078-0432.c.6528971
Autor:
Juanita S. Lopez, Nina Tunariu, Johann S. de Bono, Udai Banerji, Anna R. Minchom, Jonathan Ratoff, Joo Ern Ang, Malaka Ameratunga, Miriam Estevez Timon, Dan Bar, Andra Curcean, Mariana Scaranti, Irene Moreno Candilejo, Crescens Tiu, Angelika Terbuch
Figure S1A. Correlation of patterns of DILD as per ATS/ERS classification and clinical severity. AIP correlated significantly with worse severity (P=0.002). NSIP, non-specific interstitial pneumonia; COP, cryptogenic organizing pneumonia; AIP, acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b224b05afd94408f64a03c6a1086a4d3
https://doi.org/10.1158/1078-0432.22475021.v1
https://doi.org/10.1158/1078-0432.22475021.v1
Autor:
Ruth Riisnaes, Christina Guo, Priya Sriskandarajah, Maxime Chénard-Poirier, Jenny King, Samuel John Harris, Yuji Ishikawa, Emma Hall, Juanita Lopez, Anna Minchom, Nina Tunariu, Johann S. de Bono, Wen Xu, Suzanne Carreira, Anastasia Constantinidou, Alison Turner, Kiyohiko Nakai, Udai Banerji, Bristi Basu, Mariana Scaranti, Desamparados Roda, Laura Finneran, Irene Moreno Candilejo, Maria de Miguel, Mona Parmar, Martin Kaiser
Publikováno v:
The Lancet. Oncology
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Background CH5126766 (also known as VS-6766, and previously named R05126766), a novel MEK-pan-RAF inhibitor, has shown antitumour activity across various solid tumours; however, its initial development was limited by toxicity. We aimed to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46db17046412a4a29b4e676d09dfa814
https://doi.org/10.1016/s1470-2045(20)30464-2
https://doi.org/10.1016/s1470-2045(20)30464-2
Autor:
Miriam Estevez Timon, Juanita Lopez, Mariana Scaranti, Joo Ern Ang, Dan Bar, Anna Minchom, Johann S. de Bono, Udai Banerji, Malaka Ameratunga, Andra Curcean, Crescens Tiu, Nina Tunariu, Jonathan Ratoff, Irene Moreno Candilejo, Angelika Terbuch
Publikováno v:
Clinical Cancer Research. 26:4805-4813
Purpose: Drug-induced interstitial lung disease (DILD) is a rare, but potentially fatal toxicity. Clinical and radiological features of DILD in the early experimental setting are poorly described. Patients and Methods: A total of 2,499 consecutive pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc2da2b7b6504cf766ba76aa0ab885c
https://doi.org/10.1158/1078-0432.ccr-20-0454
https://doi.org/10.1158/1078-0432.ccr-20-0454
Autor:
Mariona Calvo, Konstantin Penkov, Alexander I. Spira, Irene Moreno Candilejo, Neal D. Shore, Tian Zhang, Begoña Mellado-Gonzalez, Teresa Alonso Gordoa, Luis Paz-Ares Rodriguez, Stefano R. Tarantolo, Juan José Soto, Robert S. Alter, Claudia Andreu-Vieyra, Timothy Bowler, Arnab K Maity, Subramanian Hariharan, Michael Thomas Schweizer
Publikováno v:
Journal of Clinical Oncology. 41:TPS282-TPS282
TPS282 Background: Enhancer of zeste homolog 2 (EZH2) encodes the histone methyltransferase component of the polycomb repressive complex-2, inducing transcriptional silencing of target genes, and is altered in cancers such as follicular lymphoma (FL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9abe4fd25b9c1717a2d8695a870fd57
https://doi.org/10.1200/jco.2023.41.6_suppl.tps282
https://doi.org/10.1200/jco.2023.41.6_suppl.tps282
Autor:
Grace Shaw, Pier Vitale Nuzzo, Edoardo Francini, Pietro Rosellini, Celestia S. Higano, Miguel Gonzalez-Velez, Irene Moreno-Candilejo, Francesca Crivelli, Antonio Cigliola, Richard M. Lee-Ying, Guido Francini, Lauren C. Harshman, Christopher Sweeney, Francesco Montagnani, Jesus Garcia-Foncillas, Alan H. Bryce, Jaime Rubio-Perez, Li Zhang, Roberto Petrioli, Nimira S. Alimohamed, Daniel Y.C. Heng, Carmelo Bengala
Publikováno v:
JAMA Network Open
Key Points Question Do patients receiving abiraterone acetate with prednisone as first-line therapy for the treatment of metastatic castration-resistant prostate cancer with bone metastases benefit from the addition of bone resorption inhibitors? Fin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d64af351dfc66c7c9a99a2092482287
http://europepmc.org/articles/PMC8299314
http://europepmc.org/articles/PMC8299314
Autor:
Maxime Chénard-Poirier, Andrew Lui, Victor Moreno, Udai Banerji, Joo Ern Ang, Juanita Lopez, Stan B. Kaye, Johann S. de Bono, Hui K Gan, Caterina Aversa, Bernard Doger, Manuel Pedregal, David Dolling, Irene Moreno Candilejo, Malaka Ameratunga, Alvaro Henrique Ingles Garces
Publikováno v:
European Journal of Cancer. 89:56-63
Although the neutrophil-lymphocyte ratio (NLR) is prognostic in many oncological settings, its significance in the immunotherapy era is unknown. Mechanistically, PD-1/PD-L1 inhibitors may alter NLR. We sought to characterise NLR kinetics in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c83beb8e187aee92b925f399ebce2d3
https://doi.org/10.1016/j.ejca.2017.11.012
https://doi.org/10.1016/j.ejca.2017.11.012