Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Irene Middelhof"'
Autor:
Anne T. Gelderloos, Marije K. Verheul, Irene Middelhof, Mary-Lène de Zeeuw-Brouwer, Robert S. van Binnendijk, Anne-Marie Buisman, Puck B. van Kasteren
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Background Previous research has shown that repeated COVID-19 mRNA vaccination leads to a marked increase of SARS-CoV-2 spike-specific serum antibodies of the IgG4 subclass, indicating far-reaching immunoglobulin class switching after booste
Externí odkaz:
https://doaj.org/article/050304379be549e89f0273602be00b10
Autor:
Marije K. Verheul, Martijn Vos, Lia de Rond, Mary-Lène De Zeeuw-Brouwer, Kim H. Nijhof, Debbie Smit, Debbie Oomen, Petra Molenaar, Marjan Bogaard, Rianne van Bergen, Irene Middelhof, Lisa Beckers, Alienke J. Wijmenga-Monsuur, Anne-Marie Buisman, Mardi C. Boer, Rob van Binnendijk, Jelle de Wit, Teun Guichelaar
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Primary COVID-19 vaccination for children, 5-17 years of age, was offered in the Netherlands at a time when a substantial part of this population had already experienced a SARS-CoV-2 infection. While vaccination has been shown effective, underlying i
Externí odkaz:
https://doaj.org/article/b55612d3ade84cd7bb9f7e2552aa2f1a
Autor:
Harrie Besselink, Bérénice Collet, Bart van der Burg, Sander C. van der Linden, Matthijs Naderman, Abraham Brouwer, Irene Middelhof, Nadia el Abdellaoui, Eszter Simon, Hai yen Man
Publikováno v:
Collet, B, Simon, E, van der Linden, S, el Abdellaoui, N, Naderman, M, Man, H Y, Middelhof, I, van der Burg, B, Besselink, H & Brouwer, A 2020, ' Evaluation of a panel of in vitro methods for assessing thyroid receptor β and transthyretin transporter disrupting activities ', Reproductive Toxicology, vol. 96, pp. 432-444 . https://doi.org/10.1016/j.reprotox.2019.05.011
Reproductive Toxicology, 96, 432-444. Elsevier Inc.
Reproductive Toxicology, 96, 432-444. Elsevier Inc.
We developed a thyroid testing panel to assess endocrine disrupting chemicals (EDCs) capacities to bind either the thyroid receptor β (TRβ) or the thyroid hormones transporter transthyretin (TTR). We first stably transfected a human U2OS cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a19defddf0deb3321d21e885db3a85
https://doi.org/10.1016/j.reprotox.2019.05.011
https://doi.org/10.1016/j.reprotox.2019.05.011
Autor:
Irene Middelhof, Hai yen Man, Rosan B. van der Lee, Bart van der Burg, Abraham Brouwer, Harrie Besselink, Barbara M.A. van Vugt-Lussenburg
Publikováno v:
Reproductive Toxicology, 75, 40-48. Elsevier Inc.
van Vugt-Lussenburg, B M A, van der Lee, R B, Man, H Y, Middelhof, I, Brouwer, A, Besselink, H & van der Burg, B 2018, ' Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity ', Reproductive Toxicology, vol. 75, pp. 40-48 . https://doi.org/10.1016/j.reprotox.2017.11.005
van Vugt-Lussenburg, B M A, van der Lee, R B, Man, H Y, Middelhof, I, Brouwer, A, Besselink, H & van der Burg, B 2018, ' Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity ', Reproductive Toxicology, vol. 75, pp. 40-48 . https://doi.org/10.1016/j.reprotox.2017.11.005
Identification and monitoring of so-called endocrine-disrupting compounds has received ample attention; both the OECD and the United States Environmental Protection Agency (US EPA) have designed tiered testing approaches, involving in vitro bioassays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9fe59be495d00a2bf72d13dc64f362
https://pubmed.ncbi.nlm.nih.gov/29162470
https://pubmed.ncbi.nlm.nih.gov/29162470