Increased Cortical Inhibition in Autism-Linked Neuroligin-3R451C Mice Is Due in Part to Loss of Endocannabinoid Signaling.

Autor: Haley E Speed, Irene Masiulis, Jay R Gibson, Craig M Powell

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0140638 (2015)

A single, maternally inherited, X-linked point mutation leading to an arginine to cysteine substitution at amino acid 451 (R451C) of Neuroligin 3 (NLGN3R451C) is a likely cause of autism in two brothers. Knockin mice expressing the Nlgn3R451C mutatio

Externí odkaz: https://doaj.org/article/672808c055e142e080869cdecd078b5a

Reelin protects against amyloid β toxicity in vivo

Autor: Michael Frotscher, Laura Steller, Cagil Coskun, Courtney Lane-Donovan, Irene Masiulis, Gary T. Philips, Catherine R. Wasser, Hans H. Bock, Ajeet Upadhaya, Tiina Kotti, Robert E. Hammer, Theresa Pohlkamp, Joachim Herz, Murat S. Durakoglugil

Publikováno v: Science Signaling. 8

Alzheimer's disease (AD) is a currently incurable neurodegenerative disorder and the most common form of dementia in people over the age of 65. The predominant genetic risk factor for AD is the ε4 allele encoding apolipoprotein E (ApoE4). The secret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d45af9a95a3ee33a1fa954117a12efd
https://doi.org/10.1126/scisignal.aaa6674

Developmental and adult GAP-43 deficiency in mice dynamically alters hippocampal neurogenesis and mossy fiber volume

Autor: Sarah E. Latchney, Irene Masiulis, Kimberly J. Zaccaria, James S. McCasland, Diane C. Lagace, Amelia J. Eisch, Craig M. Powell

Publikováno v: Developmental neuroscience. 36(1)

Growth Associated Protein-43 (GAP-43) is a pre-synaptic protein that plays key roles in axonal growth and guidance and in modulating synapse formation. Previous work has demonstrated that mice lacking one allele of this gene [GAP-43(+/-) mice] exhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c70da11722cffbdb005f55699df150
https://pubmed.ncbi.nlm.nih.gov/24576816

List of Contributors

Autor: Rajiv G. Agrawal, Nurith Amitai, Sara Ares-Santos, Rudy Bagnera, Robert L. Balster, Michael T. Bardo, Marsha E. Bates, Antoine Bechara, Anne Beck, Howard C. Becker, Margaret M. Benningfield, Susan E. Bergeson, Wade Berrettini, Kent C. Berridge, Charlotte A. Boettiger, Jeffrey Boissoneault, Ros Brett, Robyn Brown, Jennifer F. Buckman, Sarah E. Bulin, Robert J. Carey, Adrian Carter, Norma Castro, Natalie A. Ceballos, Vicki W. Chanon, Evonne J. Charboneau, Katrin Charlet, Roberto Ciccocioppo, Luke Clark, Seema L. Clifasefi, Alessandro Colasanti, Ronald L. Cowan, Silvia L. Cruz, Elisabet Cuyàs, Cristine L. Czachowski, Alecia Dager, Valérie Daugé, Joerg Daumann, Yan Dong, Paul D. Drew, Theodora Duka, Howard J. Edenberg, Amelia J. Eisch, Maurice R. Elphick, Gabriele Ende, Matthew C. Enkema, Magí Farré, Alex Fornito, Johan Franck, Douglas Funk, Ashley N. Gearhardt, Robert Gerlai, Mark. A. Geyer, Nathan A. Gillespie, Steven R. Goldberg, Anna E. Goudriaan, Euphrosyne Gouzoulis-Mayfrank, Nicholas J. Grahame, Noelia Granado, William C. Griffin, Jenny Häggkvist, Adam L. Halberstadt, Wayne Hall, Erin N. Harrop, Andreas Heinz, Aveline Hewetson, D. Brock Hewitt, Rebecca J. Houston, William G. Iacono, Jane E. Joseph, Zuzana Justinova, Peter W. Kalivas, Marsida Kallupi, Barbara J. Kaminski, Cynthia J.M. Kane, Thomas H. Kelly, Mary K. Kelm, Kenneth S. Kendler, Sarah L. King, Lori A. Knackstedt, Andrea Kobiella, George F. Koob, Mary Jeanne Kreek, Anh D. Lê, Andrew J. Lawrence, Bernard Le Foll, Jing Liang, Aron Lichtman, Joshua A. Lile, A. Kerstin Lindemeyer, Anne Lingford-Hughes, Marcelo F. Lopez, Valentina Lorenzetti, Hanbing Lu, Dan I. Lubman, Christian P. Müller, Chitra D. Mandyam, Athina Markou, Jennifer L. Martelle, Irene Masiulis, William J. McBride, Samuel M. McClure, Markus R. Meyer, Edward M. Meyer, Todd B. Monroe, Rosario Moratalla, Vincent N. Marty, Mickaël Naassila, Michael A. Nader, Jelena Nesic, Peter A. Neumann, Sara Jo Nixon, David Nutt, Shamsideen A. Ojelade, Richard W. Olsen, David H. Overstreet, Subhash C. Pandey, Leigh V. Panlilio, Ricardo Pardo, Greg Perlman, Kevin D. Phelan, Robert Christopher Pierce, Marc N. Potenza, Robert Prather, Dmitri Proudnikov, Peter T. Radu, Matthew Randesi, Kathryn J. Reissner, Amir H. Rezvani, Phillip D. Rivera, Mike J.F. Robinson, Terry E. Robinson, Zachary A. Rodd, David H. Root, Adrian Rothenfluh, Markus Sack, Heath D. Schmidt, Miriam Schneider, Yi Shen, Alfredo L. Sklar, Michael N. Smolka, Nadia Solowij, Barbara A. Sorg, Linda P. Spear, Igor Spigelman, Lindsay Squeglia, Jennifer A. Stark, Elliot A. Stein, David N. Stephens, Asha Suryanarayanan, Michael J. Takagi, Susan F. Tapert, Tara L. Teppen, Rafael de la Torre, Greg B. Urquhart, Antonio Verdejo-García, Elise M. Weerts, Mark O. West, Sarah Whittle, Murat Yücel, Vadim Yuferov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5001eee0c697548c9a6095671821cdb7
https://doi.org/10.1016/b978-0-12-398335-0.01002-5

ApoER2 function in the establishment and maintenance of retinal synaptic connectivity

Autor: Chad A. Dickey, Catherine Bowes Rickman, Edwin J. Weeber, Umesh K. Jinwal, Jose F. Abisambra, Kirsten G. Locke, Justin H. Trotter, Jindong Ding, Jeremy Tharkur, David G. Birch, Martin Klein, Joachim Herz, Irene Masiulis

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(40)

The cellular and molecular mechanisms responsible for the development of inner retinal circuitry are poorly understood. Reelin and apolipoprotein E (apoE), ligands of apoE receptor 2 (ApoER2), are involved in retinal development and degeneration, res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6a4369489ef81abf2fb8b03f73f36c
https://pubmed.ncbi.nlm.nih.gov/21976526