Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Irene M. Pirovano"'
Autor:
Adriaan P. IJzerman, Willem Soudijn, Cornel J.M. Kerkhof, Irene M. Pirovano, Margot W. Beukers, Anton van Weert
Publikováno v:
Biochemical Pharmacology. 46:1959-1966
Ecto-ATPase (EC 3.6.1.15) is a plasma membrane-bound enzyme which degrades extracellular triphosphate nucleotides. Although its physiological function is still unclear, the enzyme obscures the study of P 2 purinoceptors (i.e. receptors for ATP and ot
Autor:
Irene M. Pirovano, Adriaan P. IJzerman
Publikováno v:
Nucleosides and Nucleotides. 10:1177-1179
Kinetic analysis of the transport protein (both influx and efflux), usually performed with radiolabelled nucleosides such as adenosine and uridine, has provided a wealth of information regarding the various kinetic and equilibrium parameters (1).
Autor:
Helen R. Hartog-Witte, Meindert Danhof, Eleonora M. Van der Werten, Arthur Van Aerschot, Adriaan P. IJzerman, Margeris J. Lidaks, Irene M. Pirovano, Ron A.A. Mathôt, Jacobien K. Von Frijtag Drabbe Künzel, Willem Soudijn, H. C. P. F. Roelen
Publikováno v:
European journal of pharmacology, 290(3), 189-199. Elsevier
A series of 8-substituted adenosine and theophylline-7-riboside analogues (28 and 9 compounds, respectively) was tested on adenosine A1 and A2A receptors as an extensive exploration of the adenosine C8-region. Alkylamino substituents at the 8-positio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4186c7d5763626f33f8be37bcb4887
https://pure.amc.nl/en/publications/8substituted-adenosine-and-theophylline7riboside-analogues-as-potential-partial-agonists-for-the-adenosine-a1-receptor(b797ad4b-51ca-4d3e-b0da-c31e7b665a5b).html
https://pure.amc.nl/en/publications/8substituted-adenosine-and-theophylline7riboside-analogues-as-potential-partial-agonists-for-the-adenosine-a1-receptor(b797ad4b-51ca-4d3e-b0da-c31e7b665a5b).html
Publikováno v:
European journal of pharmacology. 189(6)
The zero-trans influx of uridine in human erythrocytes is inhibited by lidoflazine and analogs thereof. The concentrations required for inhibition of nucleoside transport were higher when the compounds were simultaneously added with uridine than upon
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 172:185-193
The affinities of a series of N6-(ω-aminoalkyl)adenosines as probes for A1 and A2 adenosine receptors were determined in various radioligand binding assays and the intrinsic activities were measured in adenylate cyclase assays. Clear species differe