Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Irene M J Eurlings"'
Autor:
Irene M J Eurlings, Niki L Reynaert, Twan van den Beucken, Harry R Gosker, C C de Theije, Fien M Verhamme, Ken R Bracke, Emiel F M Wouters, Mieke A Dentener
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e107757 (2014)
In COPD, matrix remodeling contributes to airflow limitation. Recent evidence suggests that next to fibroblasts, the process of epithelial-mesenchymal transition can contribute to matrix remodeling. CSE has been shown to induce EMT in lung epithelial
Externí odkaz:
https://doaj.org/article/2a1f242076c345389bba66b876aae1e5
Autor:
Cheryl van de Wetering, Yvonne M. W. Janssen-Heininger, Emiel F.M. Wouters, Jos van der Velden, Evi M. Mercken, Scott W. Aesif, Rafael de Cabo, Niki L. Reynaert, Irene M. J. Eurlings, Mieke A. Dentener
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology, 56(3), 393-401. American Thoracic Society
Lung tissue remodeling in chronic obstructive pulmonary disease (COPD) is characterized by airway wall thickening and/or emphysema. Although the bronchial and alveolar compartments are functionally independent entities, we recently showed comparable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67defa38a7e3b5756346687bfba2e974
https://cris.maastrichtuniversity.nl/en/publications/6780f687-28ee-4bc9-9b0c-c52b0f477d8c
https://cris.maastrichtuniversity.nl/en/publications/6780f687-28ee-4bc9-9b0c-c52b0f477d8c
Autor:
Irene M. J. Eurlings, C. C. de Theije, D.R. Sell, Niki L. Reynaert, Harry R. Gosker, Vincent M. Monnier, Poornima Gopal
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1852(5), 992-1000. Elsevier Science
The receptor for advanced glycation end products (RAGE) is a multi-ligand receptor. Alternative splicing and enzymatic shedding produce soluble forms that protect against damage by ligands including Advanced Glycation End products (AGEs). A link betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c73424fe5bced1ed9f75290babc107
Autor:
Niki L. Reynaert, Juanita H. J. Vernooy, Mieke A. Dentener, Emiel F.M. Wouters, Evi M. Mercken, Ken R. Bracke, Irene M. J. Eurlings, Rafael de Cabo
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology, 307(7), L557-L565. American Physiological Society
Remodeling in chronic obstructive pulmonary disease (COPD) has at least two dimensions: small airway wall thickening and destruction of alveolar walls. Recently we showed comparable alterations of the extracellular matrix (ECM) compounds collagen, hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2106d9e4e10c8b0e9d15efd3912420c3
https://cris.maastrichtuniversity.nl/en/publications/c6f6c14e-ddde-4e0d-9126-71f71614b245
https://cris.maastrichtuniversity.nl/en/publications/c6f6c14e-ddde-4e0d-9126-71f71614b245
Autor:
Yvonne M. W. Janssen-Heininger, Mieke A. Dentener, Irene M. J. Eurlings, Jos van der Velden, Emiel F.M. Wouters, Evi M. Mercken, Rafael de Cabo, Scott Aesif, Niki L. Reynaert
Publikováno v:
3.3 Mechanisms of Lung Injury and Repair.
We showed that in mice constitutively overexpressing TNFα in type II pneumocytes (SPC-TNFα) airway and alveolar extracellular matrix remodeling are similar and comparable to COPD patients (1,2). Epithelial cells can contribute to matrix remodeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35af32608cd7fde2a52028486cf42152
https://doi.org/10.1183/13993003.congress-2015.pa5058
https://doi.org/10.1183/13993003.congress-2015.pa5058
Autor:
Wolfgang Drommer, Catrin Albrecht, Paul Borm, Irene M. J. Eurlings, Niki L. Reynaert, Roel P. F. Schins, Timothy N. Perkins, Paul Peeters, Emiel F.M. Wouters
Publikováno v:
Particle and Fibre Toxicology
Particle and Fibre Toxicology, 11(1):58. BioMed Central Ltd
Particle and Fibre Toxicology, 11(1):58. BioMed Central Ltd
Rationale Mineral particles in the lung cause inflammation and silicosis. In myeloid and bronchial epithelial cells the inflammasome plays a role in responses to crystalline silica. Thioredoxin (TRX) and its inhibitory protein TRX-interacting protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fb26a2e6dd2182054ec8227b90cd01
http://europepmc.org/articles/PMC4243278
http://europepmc.org/articles/PMC4243278
Autor:
Gernot Rohde, Jack P.M. Cleutjens, Carine J Peutz, Niki L. Reynaert, Emiel F.M. Wouters, Mieke A. Dentener, Irene M. J. Eurlings
Publikováno v:
BMC Pulmonary Medicine
BMC Pulmonary Medicine, 14(1):90. BioMed Central Ltd
BMC Pulmonary Medicine, 14(1):90. BioMed Central Ltd
Background Remodelling in COPD has at least two dimensions: small airway wall thickening and destruction of alveolar walls. Recent studies indicate that there is some similarity between alveolar and small airway wall matrix remodelling. The aim of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f8261cf8343b35b739f6f89030512b
https://pubmed.ncbi.nlm.nih.gov/24886452
https://pubmed.ncbi.nlm.nih.gov/24886452