Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Irene Locatelli"'
Autor:
Chiara Venegoni, Filippo Pederzoli, Irene Locatelli, Elisa Alchera, Laura Martinez-Vidal, Alessia Di Coste, Marco Bandini, Andrea Necchi, Francesco Montorsi, Andrea Salonia, Marco Moschini, Jithin Jose, Federico Scarfò, Roberta Lucianò, Massimo Alfano
Publikováno v:
Matrix Biology Plus, Vol 23, Iss , Pp 100154- (2024)
Background: Non-muscle invasive bladder cancer (NMIBC) patients are affected by a high risk of recurrence. The topography of collagen fibers represents a hallmark of the neoplastic extracellular microenvironment. Objective: Assess the topographic cha
Externí odkaz:
https://doaj.org/article/3e69f26c40514915978f46fcadca1278
Autor:
Laura Martinez-Vidal, Claudia Testi, Emanuele Pontecorvo, Filippo Pederzoli, Elisa Alchera, Irene Locatelli, Chiara Venegoni, Antonello Spinelli, Roberta Lucianò, Andrea Salonia, Alessandro Podestà, Giancarlo Ruocco, Massimo Alfano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Bladder mechanical properties are critical for organ function and tissue homeostasis. Therefore, alterations of tissue mechanics are linked to disease onset and progression. This study aims to characterize the tissue elasticity of the murine
Externí odkaz:
https://doaj.org/article/3f5299549f4c44e2a5f8cd73da220f4b
Autor:
Massimo Alfano, Elisa Alchera, Angelina Sacchi, Alessandro Gori, Giacomo Quilici, Irene Locatelli, Chiara Venegoni, Roberta Lucianò, Anna Maria Gasparri, Barbara Colombo, Giulia Taiè, Jithin Jose, Paolo Armanetti, Luca Menichetti, Giovanna Musco, Andrea Salonia, Angelo Corti, Flavio Curnis
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Early detection and removal of bladder cancer in patients is crucial to prevent tumor recurrence and progression. Because current imaging techniques may fail to detect small lesions of in situ carcinomas, patients with bladder can
Externí odkaz:
https://doaj.org/article/cfb37e03030141809110415c2d80a662
Autor:
Elisa Alchera, Matteo Monieri, Mirko Maturi, Irene Locatelli, Erica Locatelli, Silvia Tortorella, Angelina Sacchi, Angelo Corti, Manuela Nebuloni, Roberta Lucianò, Filippo Pederzoli, Francesco Montorsi, Andrea Salonia, Sandra Meyer, Jithin Jose, Pierangela Giustetto, Mauro Comes Franchini, Flavio Curnis, Massimo Alfano
Publikováno v:
Photoacoustics, Vol 28, Iss , Pp 100400- (2022)
Detection and removal of bladder cancer lesions at an early stage is crucial for preventing tumor relapse and progression. This study aimed to develop a new technological platform for the visualization of small and flat urothelial lesions of high-gra
Externí odkaz:
https://doaj.org/article/ba6a54ba8e8040519884c8b617e052a3
Aging, inflammation and DNA damage in the somatic testicular niche with idiopathic germ cell aplasia
Autor:
Massimo Alfano, Anna Sofia Tascini, Filippo Pederzoli, Irene Locatelli, Manuela Nebuloni, Francesca Giannese, Jose Manuel Garcia-Manteiga, Giovanni Tonon, Giada Amodio, Silvia Gregori, Alessandra Agresti, Francesco Montorsi, Andrea Salonia
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Molecular mechanisms associated with human germ cell aplasia in infertile men remain undefined. Here the authors perform single-cell transcriptome profiling to highlight differentially expressed genes and pathways in each somatic cell type in testes
Externí odkaz:
https://doaj.org/article/72d44dea6e06424a96786fa8a4b23932
Autor:
Francesco Pellegrino, Arianna Coghi, Giovanni Lavorgna, Walter Cazzaniga, Edoardo Guazzoni, Irene Locatelli, Isabella Villa, Simona Bolamperti, Nadia Finocchio, Massimo Alfano, Roberta Lucianò, Alberto Briganti, Francesco Montorsi, Andrea Salonia, Ilaria Cavarretta
Publikováno v:
Translational Oncology, Vol 14, Iss 11, Pp 101211- (2021)
Aim: Since its discovery Prostate Specific Antigen (PSA), also referred to as kallikrein-3 (KLK3), has been used as standard circulating biomarker for prostate cancer (PCa). However, its specificity remains not adequate and its mechanism of action st
Externí odkaz:
https://doaj.org/article/2bbe99ecfaa54d1fb63f2b47de5c61e5
Autor:
Massimo Alfano, Irene Locatelli, Cristina D’Arrigo, Marco Mora, Giovanni Vozzi, Aurora De Acutis, Roberta Pece, Sara Tavella, Delfina Costa, Alessandro Poggi, Maria Raffaella Zocchi
Publikováno v:
Cancers, Vol 14, Iss 1, p 259 (2022)
Purpose: The biochemical composition and architecture of the extracellular matrix (ECM) is known to condition development and invasiveness of neoplasms. To clarify this point, we analyzed ECM stiffness, collagen cross-linking and anisotropy in lymph
Externí odkaz:
https://doaj.org/article/27c359e1b85943ad945c17a43707730d
Autor:
Elena Rainero, Cristina Cianflone, Paolo Ettore Porporato, Federica Chianale, Valeria Malacarne, Valentina Bettio, Elisa Ruffo, Michele Ferrara, Fabio Benecchia, Daniela Capello, Wolfgang Paster, Irene Locatelli, Alessandra Bertoni, Nicoletta Filigheddu, Fabiola Sinigaglia, Jim C Norman, Gianluca Baldanzi, Andrea Graziani
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97144 (2014)
Diacylglycerol kinase α (DGKα), by phosphorylating diacylglycerol into phosphatidic acid, provides a key signal driving cell migration and matrix invasion. We previously demonstrated that in epithelial cells activation of DGKα activity promotes cy
Externí odkaz:
https://doaj.org/article/66b47552bef645f1b45c28e4c5ca2e51
Autor:
Massimo Alfano, Elisa Alchera, Angelina Sacchi, Alessandro Gori, Irene Locatelli, Anna Maria Gasparri, Barbara Colombo, Giulia Anderluzzi, Paolo Armanetti, Luca Minichetti, Andrea Salonia, Angelo Corti, Flavio Curnis
Publikováno v:
Cancer Research. 83:2381-2381
Early detection and removal of bladder cancer (BC) is crucial to prevent tumor recurrence and progression. Various imaging modalities have been used to diagnose BC, including computed tomography urography, intravenous urography, ultrasound echography
Autor:
Ioannis Andrikos, Kostas Stefanou, Christos Bellos, George Stergios, Elisa Alchera, Irene Locatelli, Massimo Alfano
Publikováno v:
Computer Methods and Programs in Biomedicine. 232:107448