Duchenne muscular dystrophy cell culture models created by CRISPR/Cas9 gene editing and their application in drug screening

Autor: E. Ruiz-Del-Yerro, Aina Anton-Martinez, Javier Poyatos-Garcia, Edurne Albiasu-Arteta, Laura de la Puente-Ovejero, Gabriela Gonzalez-Iglesias, Patricia Soblechero-Martín, Virginia Arechavala-Gomeza, I. Garcia-Jimenez, Irene Larranaga-Aiestaran, Federico Gonzalez, Andrea López-Martínez

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
SCIENTIFIC REPORTS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

Gene editing methods are an attractive therapeutic option for Duchenne muscular dystrophy, and they have an immediate application in the generation of research models. To generate myoblast cultures that could be useful in in vitro drug screening, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec490975a384fc3fca7b2fbba35f0d67
https://doi.org/10.1038/s41598-021-97730-5

Duchenne muscular dystrophy cell culture models created by CRISPR/Cas9 gene editing and their application in drug screening

Autor: Patricia Soblechero-Martín, Edurne Albiasu-Arteta, Aina Anton-Martinez, Laura de la Puente-Ovejero, Iker Garcia-Jimenez, Gabriela González-Iglesias, Irene Larrañaga-Aiestaran, Andrea López-Martínez, Javier Poyatos-García, Estíbaliz Ruiz-Del-Yerro, Federico Gonzalez, Virginia Arechavala-Gomeza

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)

Abstract Gene editing methods are an attractive therapeutic option for Duchenne muscular dystrophy, and they have an immediate application in the generation of research models. To generate myoblast cultures that could be useful in in vitro drug scree

Externí odkaz: https://doaj.org/article/b44a47c08080402c9e25284c95635762