Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Irene L. Noronha"'
Autor:
Camilla Fanelli, Ana L. R. Francini, Giovanna A. Celestrino, Flávio Teles, Ana P. Barbosa, Paloma Noda, Leandro R. Iannuzzi, Cristiane R. Guzzo, Felipe M. Ornellas, Irene L. Noronha
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract CKD progression depends on the activation of an intricate set of hemodynamic and inflammatory mechanisms, promoting renal leukocyte infiltration, inflammation and fibrosis, leading to renal function loss. There are currently no specific drug
Externí odkaz:
https://doaj.org/article/2a1db773b9b246faae319ec53548a748
Autor:
Jonathan Barratt, Brad Rovin, Muh Geot Wong, Charles E. Alpers, Stewart Bieler, Ping He, Jula Inrig, Radko Komers, Hiddo J.L. Heerspink, Alex Mercer, Irene L. Noronha, Jai Radhakrishnan, Michelle N. Rheault, William Rote, Howard Trachtman, Hernán Trimarchi, Vlado Perkovic
Publikováno v:
Kidney International Reports, Vol 8, Iss 5, Pp 1043-1056 (2023)
Introduction: Sparsentan is a novel single-molecule dual endothelin angiotensin receptor antagonist with hemodynamic and anti-inflammatory properties and is not an immunosuppressant. The ongoing phase 3 PROTECT trial examines sparsentan in adults wit
Externí odkaz:
https://doaj.org/article/25a866cd50534c7d82716666703db077
Autor:
Irene L. Noronha, Guilherme P. Santa-Catharina, Lucia Andrade, Venceslau A. Coelho, Wilson Jacob-Filho, Rosilene M. Elias
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
In the last decades, improvements in the average life expectancy in the world population have been associated with a significant increase in the proportion of elderly people, in parallel with a higher prevalence of non-communicable diseases, such as
Externí odkaz:
https://doaj.org/article/2b2c58017c9b43508b4c83a2a6a66049
Autor:
Marcelo Augusto Duarte Silveira, José Manuel Condor Capcha, Talita Rojas Sanches, Roberto de Sousa Moreira, Margot S. Garnica, Maria Heloisa Shimizu, Andresa Berretta, Flávio Teles, Irene L. Noronha, Lúcia Andrade
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Sepsis is the leading cause of acute kidney injury (AKI) and lung injury worldwide. Despite therapeutic advances, sepsis continues to be associated with high mortality. Because Brazilian green propolis (GP) has promising anti-inflammatory, a
Externí odkaz:
https://doaj.org/article/f7924bf5dd5d4a32a3cbead01b528b22
Autor:
Venceslau A. Coelho, Giovani GN. Santos, Carla M. Avesani, Cicero Italo L. Bezerra, Luana Cristina A. Silva, Julia C. Lauar, Bengt Lindholm, Peter Stenvinkel, Wilson Jacob-Filho, Irene L. Noronha, Roberto Zatz, Rosa M. A. Moysés, Rosilene M. Elias
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Renal replacement therapy (RRT) is usually indicated for patients with chronic kidney disease (CKD) with glomerular filtration rate below 10 ml/ml/min/1.73m2. However, the need for RRT and timing of dialysis initiation are debatab
Externí odkaz:
https://doaj.org/article/064ce3e066564f3f866a1299a2623bd6
Autor:
Bruno Henrique Dantas Ribeiro, Vanessa Suemi Takenaka, Felipe Sbrolini Borges, Thales Franco de Andrade, Sibele Braga Lessa, Jorge Marcelo Padilla Mancero, Irene L. Noronha, André Ibrahim David
Publikováno v:
Brazilian Journal of Nephrology, Vol 42, Iss 3, Pp 370-374 (2020)
Abstract Encapsulating Peritoneal Sclerosis (EPS) is a severe and rare condition frequently associated with peritoneal dialysis, characterized by bowel obstruction, with lethal consequences in 20% of the patients. The disease presents as a mass of fi
Externí odkaz:
https://doaj.org/article/8cca9a2a138d468d86abf4159bb808fe
Autor:
Everidiene K. V. B. Silva, Camila G. Bomfim, Ana P. Barbosa, Paloma Noda, Irene L. Noronha, Bianca H. V. Fernandes, Rafael R. G. Machado, Edison L. Durigon, Sergio Catanozi, Letícia G. Rodrigues, Fabiana Pieroni, Sérgio G. Lima, Walcy R. Teodoro, Zelita A. J. Queiroz, Lizandre K. R. Silveira, Ives Charlie-Silva, Vera L. Capelozzi, Cristiane R. Guzzo, Camilla Fanelli
Publikováno v:
PLoS ONE, Vol 17, Iss 5 (2022)
The SARS-CoV-2 pandemic have been affecting millions of people worldwide, since the beginning of 2020. COVID-19 can cause a wide range of clinical symptoms, which varies from asymptomatic presentation to severe respiratory insufficiency, exacerbation
Externí odkaz:
https://doaj.org/article/60c67a27aa8742a8ae2d4f5cecf77216
Autor:
Marina P. C. Maires, Krislley R. Pereira, Everidiene K. V. B. Silva, Victor H. R. Souza, Flavio Teles, Paulyana F. Barbosa, Margoth R. Garnica, Felipe M. Ornellas, Irene L. Noronha, Camilla Fanelli
Publikováno v:
Stem Cells International, Vol 2022 (2022)
Global prevalence of chronic kidney disease (CKD) has increased considerably in the recent decades. Overactivity of the renin-angiotensin-aldosterone system (RAAS), associated to renal inflammation and fibrosis, contributes to its evolution. The trea
Externí odkaz:
https://doaj.org/article/449917f72e76474e945ffb88a2ac604a
Autor:
Filipe M. O. Silva, Elerson C. Costalonga, Cleonice Silva, Ana C. O. Carreira, Samirah A. Gomes, Mari C. Sogayar, Camilla Fanelli, Irene L. Noronha
Publikováno v:
Molecular Medicine, Vol 25, Iss 1, Pp 1-18 (2019)
Abstract Background Peritoneal fibrosis (PF) represents a long-term complication of peritoneal dialysis (PD), affecting peritoneal membrane (PM) integrity and function. Understanding the mechanisms underlying PF development in an uremic environment a
Externí odkaz:
https://doaj.org/article/1d71076c97ce453c8267a45c5b4fee0e
Autor:
Rosana M. C. Bastos, Antônio Simplício-Filho, Christian Sávio-Silva, Luiz Felipe V. Oliveira, Giuliano N. F. Cruz, Eliza H. Sousa, Irene L. Noronha, Cristóvão L. P. Mangueira, Heloísa Quaglierini-Ribeiro, Gleice R. Josefi-Rocha, Érika B. Rangel
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3842 (2022)
Diabetes mellitus (DM) burden encompasses diabetic kidney disease (DKD), the leading cause of end-stage renal disease worldwide. Despite compelling evidence indicating that pharmacological intervention curtails DKD progression, the search for non-pha
Externí odkaz:
https://doaj.org/article/e1e7bc67dd4b492a911eec9f1d2458c4