Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Irene Kalisz"'
Autor:
Zachary K. Sagawa, Cristina Goman, Aude Frevol, Azra Blazevic, Janice Tennant, Bridget Fisher, Tracey Day, Stephen Jackson, Franck Lemiale, Leon Toussaint, Irene Kalisz, Joe Jiang, Lisa Ondrejcek, Raodoh Mohamath, Julie Vergara, Alan Lew, Anna Marie Beckmann, Corey Casper, Daniel F. Hoft, Christopher B. Fox
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Here the authors present results from a randomized, double-blinded Phase 1 clinical trial, testing a thermostable presentation of a clinical-stage adjuvanted subunit tuberculosis vaccine candidate. The vaccine candidate is safe and well tolerated, an
Externí odkaz:
https://doaj.org/article/0416e608bded4e49acce0289f6385372
Autor:
Isabela Silva de Castro, Giacomo Gorini, Rosemarie Mason, Jason Gorman, Massimiliano Bissa, Mohammad A. Rahman, Anush Arakelyan, Irene Kalisz, Stephen Whitney, Manuel Becerra-Flores, Eric Ni, Kristina Peachman, Hung V. Trinh, Michael Read, Mei-Hue Liu, Donald Van Ryk, Dominic Paquin-Proulx, Zhanna Shubin, Marina Tuyishime, Jennifer Peele, Mohammed S. Ahmadi, Raffaello Verardi, Juliane Hill, Margaret Beddall, Richard Nguyen, James D. Stamos, Dai Fujikawa, Susie Min, Luca Schifanella, Monica Vaccari, Veronica Galli, Melvin N. Doster, Namal P.M. Liyanage, Sarkis Sarkis, Francesca Caccuri, Celia LaBranche, David C. Montefiori, Georgia D. Tomaras, Xiaoying Shen, Margherita Rosati, Barbara K. Felber, George N. Pavlakis, David J. Venzon, William Magnanelli, Matthew Breed, Josh Kramer, Brandon F. Keele, Michael A. Eller, Claudia Cicala, James Arthos, Guido Ferrari, Leonid Margolis, Marjorie Robert-Guroff, Peter D. Kwong, Mario Roederer, Mangala Rao, Timothy J. Cardozo, Genoveffa Franchini
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102047- (2021)
Summary: The efficacy of ALVAC-based HIV and SIV vaccines in humans and macaques correlates with antibodies to envelope variable region 2 (V2). We show here that vaccine-induced antibodies to SIV variable region 1 (V1) inhibit anti-V2 antibody-mediat
Externí odkaz:
https://doaj.org/article/0f4c13b40f5b4bb9bf78e5a35a226d78
Autor:
Iskra Tuero, Venkatramanan Mohanram, Thomas Musich, Leia Miller, Diego A Vargas-Inchaustegui, Thorsten Demberg, David Venzon, Irene Kalisz, V S Kalyanaraman, Ranajit Pal, Maria Grazia Ferrari, Celia LaBranche, David C Montefiori, Mangala Rao, Monica Vaccari, Genoveffa Franchini, Susan W Barnett, Marjorie Robert-Guroff
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005101 (2015)
Many viral infections, including HIV, exhibit sex-based pathogenic differences. However, few studies have examined vaccine-related sex differences. We compared immunogenicity and protective efficacy of monomeric SIV gp120 with oligomeric SIV gp140 in
Externí odkaz:
https://doaj.org/article/03dd5126b48944a0890b2f5773c2155f
Autor:
Nikolai Petrovsky, Vaniambadi S. Kalyanaraman, Celia C. LaBranche, Veena Menon, Asma Ashraf, Irene Kalisz, Stephen Whitney, Victor I. Ayala, Sneha P. Rangaswamy, Lindsey Galmin, David C. Montefiori, Ranajit Pal
Publikováno v:
Journal of General Virology
The partial success of the RV144 trial underscores the importance of envelope-specific antibody responses for an effective HIV-1 vaccine. Oligomeric HIV-1 envelope proteins delivered with a potent adjuvant are expected to elicit strong antibody respo
Autor:
Diego A. Vargas-Inchaustegui, Indresh K. Srivastava, David Venzon, Eun Mi Lee, Vaniambadi S. Kalyanaraman, David C. Montefiori, Janet DiPasquale, Thorsten Demberg, Irene Kalisz, Ruth M. Ruprecht, Stanley Aladi, Susan W. Barnett, Seraphin Kuate, Ranajit Pal, Marjorie Robert-Guroff, Egidio Brocca-Cofano
Publikováno v:
Virology. 440:210-221
Previously, priming rhesus macaques with Adenovirus type 5 host range mutant-recombinants encoding Tat and Env and boosting with Tat and Env protein in MPL-SE controlled chronic viremia by 4 logs following homologous intravenous SHIV89.6P challenge.
Autor:
Katherine McKinnon, Vaniambadi S. Kalyanaraman, Thorsten Demberg, Marjorie Robert-Guroff, Irene Kalisz, Egidio Brocca-Cofano, Eun Mi Lee, Diego A. Vargas-Inchaustegui, David Venzon, Peng Xiao, Janet DiPasquale
Publikováno v:
Journal of Virology. 86:12591-12604
Human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) infection causes B-cell dysregulation and the loss of memory B cells in peripheral blood mononuclear cells (PBMC). These effects are not completely reversed by antiretroviral trea
Autor:
Marjorie Robert-Guroff, Jun Zhao, Brandon F. Keele, Seraphin Kuate, Peng Xiao, David C. Montefiori, Eun Mi Lee, Vaniambadi S. Kalyanaraman, Irene Kalisz, Claudio Fenizia, Michael A. Thomas, Janet DiPasquale, David Venzon, L. Jean Patterson, Egidio Brocca-Cofano, Ranajit Pal
Publikováno v:
Journal of Virology. 86:4644-4657
We have shown that sequential replicating adenovirus type 5 host range mutant human immunodeficiency virus/simian immunodeficiency virus (HIV/SIV) recombinant priming delivered first intranasally (i.n.) plus orally and then intratracheally (i.t.), fo
Autor:
Vaniambadi S. Kalyanaraman, Thorsten Demberg, Irene Kalisz, David B. Weiner, Nina Malkevich, David Venzon, Marjorie Robert-Guroff, L. Jean Patterson, Eun Mi Lee, Ebonita L. Summers, Jean D. Boyer
Publikováno v:
Journal of Virology. 82:10911-10921
Previously, combination DNA/nonreplicating adenovirus (Ad)- or poxvirus-vectored vaccines have strongly protected against SHIV89.6P, DNAs expressing cytokines have modulated immunity elicited by DNA vaccines, and replication-competent Ad-recombinant
Autor:
Jennifer Beal, David C. Montefiori, David Venzon, Nina Malkevich, Eun Mi Lee, L. Jean Patterson, Kris Aldrich, Vaniambadi S. Kalyanaraman, Thorsten Demberg, Ersell Richardson, Irene Kalisz, Ruth H. Florese, Frank A. Robey, Marjorie Robert-Guroff
Publikováno v:
Virology. 374:322-337
Previously, replicating adenovirus type 5 host range (Ad5hr)-HIV/SIV recombinant priming in combination with SIV envelope boosting, resulted in significant, durable protection in 39% of rhesus macaques after SIV mac251 challenge. Both Env-specific an
Autor:
L. Jean Patterson, Vaniambadi S. Kalyanaraman, Thorsten Demberg, Megan J. Heath, Kay Larsen, Norman L. Letvin, Birgit Korioth-Schmitz, Irene Kalisz, Adam P. Buzby, Eun Mi Lee, David Venzon, Barbara Ensoli, Richard Grant, Ruth H. Florese, Aurelio Cafaro, Dilani Dombagoda, Ranajit Pal, David C. Montefiori, Marjorie Robert-Guroff
Publikováno v:
Journal of Virology. 81:3414-3427
We previously demonstrated that replication-competent adenovirus (Ad)-simian immunodeficiency virus (SIV) recombinant prime/protein boost regimens elicit potent immunogenicity and strong, durable protection of rhesus macaques against SIVmac251. Addit