Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Irene K Yan"'
Publikováno v:
Tumor Biology, Vol 40 (2018)
Circular ribonucleic acids are non-coding ribonucleic acids that can be identified from genome sequencing studies. Although they can be readily detected, their regulation and functional role in human diseases such as cancer are unknown. Using a syste
Externí odkaz:
https://doaj.org/article/f6023b66d50a4eefaf90b97241ee944c
Autor:
Catherine Foye, Irene K Yan, Waseem David, Neha Shukla, Yacob Habboush, Lori Chase, Kristen Ryland, Vivek Kesari, Tushar Patel
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189165 (2017)
Circulating microRNAs that are associated with specific diseases have garnered much attention for use in diagnostic assays. However, detection of disease-associated miRNA can be affected by several factors such as release of contaminating cellular mi
Externí odkaz:
https://doaj.org/article/0834f96310884aa4a791e16bdabc4bcd
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0155888 (2016)
Although a key determinant of hepatic recovery after injury is active liver regeneration, the ability to detect ongoing regeneration is lacking. The restoration of liver mass after hepatectomy involves systemic changes with coordinated changes in gen
Externí odkaz:
https://doaj.org/article/c83b0f76ac4c41bbb795d0e4ec7149fe
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
The transfer of extracellular RNA is emerging as an important mechanism for intracellular communication. The ability for the transfer of functionally active RNA molecules from one cell to another within vesicles such as exosomes enables a cell to mod
Externí odkaz:
https://doaj.org/article/141b3fdedbe344bfa59d115b2b0006a7
Autor:
Santanu Bhattacharya, Krishnendu Pal, Anil K Sharma, Shamit K Dutta, Julie S Lau, Irene K Yan, Enfeng Wang, Ahmed Elkhanany, Khalid M Alkharfy, Arunik Sanyal, Tushar C Patel, Suresh T Chari, Mark R Spaller, Debabrata Mukhopadhyay
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114409 (2014)
GAIP interacting protein C terminus (GIPC) is known to play an important role in a variety of physiological and disease states. In the present study, we have identified a novel role for GIPC as a master regulator of autophagy and the exocytotic pathw
Externí odkaz:
https://doaj.org/article/09280cc855094a579ee67ad2cb4917df
Publikováno v:
Nanomaterials, Vol 14, Iss 21, p 1727 (2024)
Aptamers are short DNA or RNA sequences that adopt 3D structures and can bind to protein targets with high binding affinity and specificity. Aptamers exhibit excellent tissue penetration, are inexpensive to produce, and can be internalized by cells.
Externí odkaz:
https://doaj.org/article/002aac8706924d29aa1181ed0afdf6fe
Publikováno v:
Hepatology Communications, Vol 8, Iss 3 (2024)
Background:. Impaired natural killer (NK) cell-mediated antitumor responses contribute to the growth of liver tumors. Expression of a disintegrin and metalloprotease 9 (ADAM9) increases shedding of membrane-bound major histocompatibility complex clas
Externí odkaz:
https://doaj.org/article/ba814bc279574e57862677c40449c2e1
Autor:
Adil Ali Sayyed, Piyush Gondaliya, Irene K. Yan, James Carrington, Julia Driscoll, Anuradha Moirangthem, Tushar Patel
Publikováno v:
Nanomaterials, Vol 13, Iss 20, p 2751 (2023)
Extracellular vesicles (EVs) show promise for targeted drug delivery but face production challenges with low yields. Cell-derived nanovesicles (CDNVs) made by reconstituting cell membranes could serve as EV substitutes. In this study, CDNVs were gene
Externí odkaz:
https://doaj.org/article/0d0f651b3b944b078649dc71c7b637d9
Autor:
Kayleah M. Meneses, Prita Pandya, Jennifer A. Lindemann, Dania S. Al-Qasrawi, Ryan A. Argo, Celeste M. Weems, Danielle J. Beetler, Geraldine V. Vijay, Irene K. Yan, Joy Wolfram, Tushar Patel, Verline Justilien
Publikováno v:
Cancer Research Communications. 3:607-620
Cancer stem cells (CSC) within non–small cell lung carcinoma (NSCLC) tumors drive NSCLC progression, metastasis, relapse, and intrinsic chemoresistance. Understanding the mechanisms that support the malignant phenotypes of NSCLC CSCs may provide in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae99669bc5d033dbb3ef5287802c4b22
https://doi.org/10.1158/2767-9764.crc-22-0425
https://doi.org/10.1158/2767-9764.crc-22-0425
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 849 (2022)
The therapeutic activities elicited by mesenchymal stem cells (MSC) are in part mediated through paracrine action by the release of extracellular vesicles (EV) and secreted proteins. Collectively, these MSC-derived factors, referred to as the secreto
Externí odkaz:
https://doaj.org/article/b6e1ca07a85c49bbb73e779e65a0eff6