Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Irene Kührer"'
Autor:
Gudrun Piringer, Thomas Gruenberger, Josef Thaler, Irene Kührer, Klaus Kaczirek, Friedrich Längle, Istvan Viragos-Toth, Arno Amann, Wolfgang Eisterer, Reinhold Függer, Johannes Andel, Angelika Pichler, Judith Stift, Lidija Sölkner, Michael Gnant, Dietmar Öfner
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundTwenty percent of colorectal cancer liver metastases (CLMs) are initially resectable with a 5-year survival rate of 25%–40%. Perioperative folinic acid, 5-fluorouracil, oxaliplatin (FOLFOX) increases progression-free survival (PFS). In ad
Externí odkaz:
https://doaj.org/article/a086fc5f438c457e89f61feead205633
Autor:
Daniela Kandioler, Martina Mittlböck, Sonja Kappel, Harald Puhalla, Friedrich Herbst, Cord Langner, Brigitte Wolf, Jörg Tschmelitsch, Walter Schippinger, Günther Steger, Friedrich Hofbauer, Hellmut Samonigg, Michael Gnant, Bela Teleky, Irene Kührer
Publikováno v:
EBioMedicine, Vol 2, Iss 8, Pp 825-830 (2015)
We investigated the hypothesis that the varying treatment efficacy of adjuvant 5-fluorouracil (5FU) in stage III colon cancer is linked to the TP53 mutational status. ABCSG-90 was a prospective randomized trial in which effect of adjuvant 5FU was stu
Externí odkaz:
https://doaj.org/article/f32e15c90b3444429992ef780cd884c8
Autor:
Sonja, Kappel-Latif, Johannes, Zacherl, Michael, Hejna, Maria, Westerhoff, Dietmar, Tamandl, Ahmed, Ba-Ssalamah, Martina, Mittlböck, Brigitte, Wolf, Friedrich, Wrba, Irene, Kührer, Ursula, Pluschnig, Sebastian F, Schoppmann, Reinhold, Függer, Ronald, Zwrtek, Karl, Glaser, Josef, Karner, Friedrich, Längle, Etienne, Wenzl, Rudolf, Roka, Dietmar, Öfner, Jörg, Tschmelitsch, Michael, Hold, Felix, Keil, Michael, Gnant, Daniela, Kandioler, O, Dietze
Publikováno v:
European Surgery
Summary Background In operable esophageal cancer patients, neoadjuvant therapy benefits only those who respond to the treatment. The • Pancho trial represents the first prospective randomized trial evaluating the relevance of the mark53 status for
Autor:
Lindsay Brammen, Martina Mittlböck, Kausilia K. Krishnadath, Irene Kührer, Tamara Braunschmid, Wayne A. Phillips, Maria Westerhoff, Daniela Kandioler, Michael Gnant, Sonja Kappel-Latif
Publikováno v:
Annals of the New York Academy of Sciences, 1434(1), 46-53. Wiley-Blackwell
Technological progress within the last 15–20 years has significantly increased our knowledge about the molecular basis of cancer development, tumor progression, and treatment response. As a consequence, a vast number of biomarkers have been propose
Autor:
Jörg Tschmelitsch, Friedrich Hofbauer, Hellmut Samonigg, Sonja Kappel, Harald Puhalla, Cord Langner, Daniela Kandioler, Michael Gnant, Walter Schippinger, Bela Teleky, Irene Kührer, Friedrich Herbst, Günther G. Steger, Brigitte Wolf, Martina Mittlböck
Publikováno v:
EBioMedicine, Vol 2, Iss 8, Pp 825-830 (2015)
EBioMedicine
EBioMedicine
We investigated the hypothesis that the varying treatment efficacy of adjuvant 5-fluorouracil (5FU) in stage III colon cancer is linked to the TP53 mutational status. ABCSG-90 was a prospective randomized trial in which effect of adjuvant 5FU was stu
Autor:
Irene Kührer, Brigitte Wolf, Rainer Schmid, Bela Teleky, Belgin Akan, Martina Mittlböck, Sonja Kappel, Daniela Kandioler, Fritz Wrba
Publikováno v:
European Surgery. 42:18-23
BACKGROUND: Cell killing by ionizing radiation is triggered by DNA-damage involving the p53 gene as major player in cell death induction. p53 is frequently inactivated in cancer which prevents apoptosis after extensive DNA-damage. METHOD: We summariz
Autor:
Sebastian F. Schoppmann, Johannes Zacherl, S. Gacic, Martina Mittlböck, Brigitte Wolf, Irene Kührer, Christoph Bichler, Sonja Kappel, Gerald W. Prager, Yelena Devyatko, Ahmed Ba-Ssalamah, Ursula Pluschnig, Michael Hejna, Fritz Wrba, Daniela Kandioler
Publikováno v:
European Surgery. 40:277-283
BACKGROUND: In esophageal cancer patients neoadjuvant therapy failed to demonstrate a clear benefit in overall survival. A significant advantage can be seen in patients with complete pathological response. METHODS: This review summarizes the results
Autor:
M.R. Müller, Erich Roth, Daniela Kandioler, Sabine Zöchbauer-Müller, Adelheid End, Marcus Hudec, Martina Mittlböck, T. Bachleitner, Wilfried Eberhardt, Ronald Zwrtek, Christoph Bichler, Irene Kührer, Georgios Stamatis, Sonja Kappel, Clemens Aigner, Walter Klepetko, Victoria Tichy
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 135:1036-1041
ObjectiveThe objective of this study is to establish clinical evidence that the p53 genotype can serve as a predictive marker for response to cisplatin-based induction therapy.MethodsPatients with advanced non–small cell lung cancer who had receive
Autor:
Silvana Geleff, Fritz Wrba, F. Herbst, A. Fenzl, Peter Birner, Sebastian F. Schoppmann, Raimund Jakesz, Beata Herberger, F. Längle, Bela Teleky, Irene Kührer
Publikováno v:
European Surgery. 38:149-154
BACKGROUND: Colorectal cancer is a common cause of death throughout the world. Approximately 145,290 new cases of large bowel cancer are diagnosed each year in the United States, of which 104,950 are colon and the remainder rectal cancers. In 2005, m
Autor:
Irene Kührer, Bela Teleky
Publikováno v:
European Surgery. 38:124-128
BACKGROUND: The incidence of colon carcinoma has increased during the last years, but novel diagnostic tools have also been developed. METHODS: Review on colon carcinoma. RESULTS: The only chance in the cure of colonic carcinoma is achieved by radica