Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Irene Han-Juo Cheng"'
Autor:
Keith Jun Hao Cheong, Duen-Yi Huang, Ponarulselvam Sekar, Rou Jhen Chen, Irene Han-Juo Cheng, Chi-Ming Chan, Yuan-Shen Chen, Wan-Wan Lin
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 343 (2024)
Calcium/calmodulin-dependent serine protein kinase (CASK) is a scaffold protein and plays critical roles in neuronal synaptic formation and brain development. Previously, CASK was shown to associate with EGFR to maintain the vulval cell differentiati
Externí odkaz:
https://doaj.org/article/4c40b099beaf432193048d5d34ad2f63
Autor:
Tzu-Hsuan Huang, Yi-Sian Lin, Chiao-Wan Hsiao, Liang-Yun Wang, Musa Iyiola Ajibola, Wahab Imam Abdulmajeed, Yu-Ling Lin, Yu-Jui Li, Cho-Yi Chen, Cheng-Chang Lien, Cheng-Di Chiu, Irene Han-Juo Cheng
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Inhibitory γ-aminobutyric acid (GABA)-ergic interneurons mediate inhibition in neuronal circuitry and support normal brain function. Consequently, dysregulation of inhibition is implicated in various brain disorders. Parvalbumin (PV) and somatostati
Externí odkaz:
https://doaj.org/article/f5e31084e68641afac963fc78b986bd5
Publikováno v:
Fermentation, Vol 8, Iss 5, p 193 (2022)
Evidence suggests that various hallmarks such as amyloid overproduction, tau dysfunction, insulin resistance/diabetic mechanisms, and neuroinflammation are associated with Alzheimer’s disease (AD). This study investigated the bioactive functions of
Externí odkaz:
https://doaj.org/article/01b3385ba5574b1fbd22a5be9521894b
Autor:
Yan-Xi Chen, Phuong Thu Nguyen Le, Tsai-Teng Tzeng, Thu-Ha Tran, Anh Thuc Nguyen, Irene Han-Juo Cheng, Chi-Ying F. Huang, Young-Ji Shiao, Tsui-Ting Ching
Publikováno v:
Nutrients, Vol 13, Iss 12, p 4317 (2021)
Declines in physiological functions are the predominant risk factors for age-related diseases, such as cancers and neurodegenerative diseases. Therefore, delaying the aging process is believed to be beneficial in preventing the onset of age-related d
Externí odkaz:
https://doaj.org/article/d04a4e152043449ab597d981a23f1e5a
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-17 (2017)
Abstract Background Microglia mediate amyloid-beta peptide (Aβ)-induced neuroinflammation, which is one of the key events in the pathogenesis of Alzheimer’s disease (AD). Decoy receptor 3 (DcR3)/TNFRSF6B is a pleiotropic immunomodulator that promo
Externí odkaz:
https://doaj.org/article/20a2092529f6453eb9d7bc4db7bee042
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 5, Iss 3, Pp 424-434 (2015)
Objective: We aimed to identify biomarkers of Alzheimer's disease (AD) in order to improve diagnostic accuracy at mild stage. Methods: AD patients aged >50 years were included in the disease group. We evaluated the relationship between potential bloo
Externí odkaz:
https://doaj.org/article/bb6673ef52f3441d8c1a40e97d159e7e
Autor:
Chia-Chou Wu, Tsung-Han Tsai, Chieh Chang, Tian-Thai Lee, Che Lin, Irene Han-Juo Cheng, Mu-Chien Sun, Yung-Jen Chuang, Bor-Sen Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97902 (2014)
Upon injury, the direct damage and the subsequent secondary injury in the brain often result in chronic neurological disorders. Due to multifactorial nature of secondary injury and subsequent complex cellular responses, much of the underlying mechani
Externí odkaz:
https://doaj.org/article/7f952e6a452640f58f6533b812d86a1b
Publikováno v:
Journal of Neurochemistry. 163:26-39
Alzheimer disease (AD), a progressive neurodegenerative disorder, is mainly caused by the interaction of genetic and environmental factors. The impact of environmental factors on the genetic mutation in the amyloid precursor protein (APP) is not well
Autor:
Wahab Imam Abdulmajeed, Kai‐Yi Wang, Jei‐Wei Wu, Musa Iyiola Ajibola, Irene Han‐Juo Cheng, Cheng‐Chang Lien
Publikováno v:
The Journal of Physiology. 600:3355-3381
The hippocampus is an elongated brain structure which runs along a ventral-to-dorsal axis in rodents, corresponding to the anterior-to-posterior axis in humans. A glutamatergic cell type in the dentate gyrus (DG), the mossy cells (MCs), establishes e
Autor:
Tzu-Hsuan Huang, Yi-Sian Lin, Chiao-Wan Hsiao, Liang-Yun Wang, Ajibola, Musa Iyiola, Abdulmajeed, Wahab Imam, Yu-Ling Lin, Yu-Jui Li, Cho-Yi Chen, Cheng-Chang Lien, Cheng-Di Chiu, Irene Han-Juo Cheng
Publikováno v:
Frontiers in Cellular Neuroscience; 2023, p1-17, 17p