Supplementary Data from High Cytotoxicity of Cisplatin Nanocapsules in Ovarian Carcinoma Cells Depends on Uptake by Caveolae-Mediated Endocytosis

Autor: Anton I.P.M. de Kroon, Paul M.P. van Bergen en Henegouwen, Jan Reedijk, Ben de Kruijff, Jarno Voortman, Rutger W.H.M. Staffhorst, Irene H.L. Hamelers

Supplementary Data from High Cytotoxicity of Cisplatin Nanocapsules in Ovarian Carcinoma Cells Depends on Uptake by Caveolae-Mediated Endocytosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26055a0890a5985d8355baea392c15fd
https://doi.org/10.1158/1078-0432.22440744

Antitumor activity and biodistribution of cisplatin nanocapsules in nude mice bearing human ovarian carcinoma xenografts

Autor: Epie Boven, Kasper van der Born, Godefridus J. Peters, Irene H.L. Hamelers, Caroline A.M. Erkelens, Rutger W.H.M. Staffhorst, Anton I.P.M. de Kroon

Publikováno v: Staffhorst, R W, van der Born, K, Erkelens, CA, Hamelers, I H, Peters, G J, Boven, E & de Kroon, A I 2008, ' Antitumor activity and biodistribution of cisplatin nanocapsules in nude mice bearing human ovarian carcinoma xenografts ', Anti-Cancer Drugs, vol. 19, no. 7, pp. 721-727 . https://doi.org/10.1097/CAD.0b013e328304355f
Anti-Cancer Drugs, 19(7), 721-727. Lippincott Williams and Wilkins

Cisplatin nanocapsules represent a novel lipid formulation of the anticancer drug cis-diamminedichloridoplatinum(II) (cisplatin), characterized by an unprecedented cisplatin-to-lipid molar ratio, and exhibiting strongly increased in-vitro cytotoxicit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c797703845190c6b85ccfb9af83fdc
https://doi.org/10.1097/cad.0b013e328304355f

Comparison of fixation protocols for adherent cultured cells applied to a GFP fusion protein of the epidermal growth factor receptor

Autor: Irene H.L. Hamelers, Thomas M. Jovin, Roland Brock

Publikováno v: Cytometry. 35:353-362

Background: The analysis of the subcellular distribution of proteins is essential for the understanding of processes such as signal transduction. In most cases, the parallel analysis of multiple components requires fixation and immunofluorescence lab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::733d0b7cbaf76eb7199914b0a4233869
https://doi.org/10.1002/(sici)1097-0320(19990401)35:4<353::aid-cyto8>3.0.co

Nanocapsules of Platinum-Based Anticancer Drugs

Autor: Anton I.P.M. de Kroon, Irene H.L. Hamelers

Publikováno v: Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy ISBN: 9781603274586

One of the strategies to reduce the side effects of platinum anticancer drugs is encapsulation of the drug in a lipid formulation. Nanocapsules represent a novel lipid-based drug delivery system, with high encapsulation efficiencies of cisplatin and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c679ab00af405344d24bfe6b1237908
https://doi.org/10.1007/978-1-60327-459-3_4

Nanocapsules: a novel lipid formulation platform for platinum-based anti-cancer drugs

Autor: Anton I.P.M. de Kroon, Irene H.L. Hamelers

Publikováno v: Journal of liposome research. 17(3-4)

Platinum-based anti-cancer agents have been used for many years to treat many different types of cancer. However, the efficacy of these drugs is limited by serious side effects. One of the strategies to reduce the side effects is encapsulation of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bc2b8cae1e24d7b148391ced4df0d1
https://pubmed.ncbi.nlm.nih.gov/18027238