Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Irene H. Heijink"'
Autor:
Silke Meiners, Niki L. Reynaert, Andreas M. Matthaiou, Rishi Rajesh, Engi Ahmed, Raquel Guillamat-Prats, Irene H. Heijink, Sara Cuevas-Ocaña
Publikováno v:
Breathe, Vol 20, Iss 1 (2024)
The Translational Science Working Group at the European Respiratory Society (ERS) aims to bridge the gap between basic and clinical science by providing a platform where scientists, clinicians and experts in the respiratory field can actively shape t
Externí odkaz:
https://doaj.org/article/6c5b9196422c4cc7a5f7ae1d6761a032
Autor:
Mehmet Nizamoglu, Maunick Lefin Koloko Ngassie, Rhode A. Meuleman, Martin Banchero, Theo Borghuis, Wim Timens, Martijn C. Nawijn, Barbro N. Melgert, Irene H. Heijink, Corry-Anke Brandsma, Janette K. Burgess
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Abnormal deposition of extracellular matrix (ECM) in lung tissue is a characteristic of idiopathic pulmonary fibrosis (IPF). Increased collagen deposition is also accompanied by altered collagen organization. Collagen type XIV, a fibril-asso
Externí odkaz:
https://doaj.org/article/a8279a64c37149c6829e8aef79c36513
Autor:
Simon D. Pouwels, Alina Sigaeva, Shanna de Boer, Ilse A. Eichhorn, Lisanne Koll, Jeroen Kuipers, Romana Schirhagl, Irene H. Heijink, Janette K. Burgess, Dirk-Jan Slebos
Publikováno v:
Journal of Materials Science: Materials in Medicine, Vol 34, Iss 7, Pp 1-13 (2023)
Abstract Endoscopic implantation of medical devices for the treatment of lung diseases, including airway stents, unidirectional valves and coils, is readily used to treat central airway disease and emphysema. However, granulation and fibrotic tissue
Externí odkaz:
https://doaj.org/article/1ba4a7782bcb446bb0a4abb24a31640a
Autor:
Dennis Kruk, Anna C. Y. Yeung, Alen Faiz, Nick H. T. ten Hacken, Wim Timens, Toin H. van Kuppevelt, Willeke Daamen, Danique Hof, Martin C. Harmsen, Mauricio Rojas, Irene H. Heijink
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by irreversible lung tissue damage. Novel regenerative strategies are urgently awaited. Cultured mesenchymal stem/stromal cells (MSCs) have shown promising results in e
Externí odkaz:
https://doaj.org/article/8b2a51adaa564845abc7e12fc325f547
Autor:
Marissa Wisman, Mehmet Nizamoglu, Jacobien A. Noordhoek, Wim Timens, Janette K. Burgess, Irene H. Heijink
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
In idiopathic pulmonary fibrosis (IPF) constant epithelial micro-injury and aberrant interactions within the stromal micro-environment lead to abnormal alveolar repair and fibrosis. We hypothesized that alveolar epithelial regenerative responses in I
Externí odkaz:
https://doaj.org/article/cd370063ba214204a627d9caa69cbadd
Autor:
Sara Cuevas Ocaña, Natalia El-Merhie, Merian E. Kuipers, Mareike Lehmann, Sara Rolandsson Enes, Carola Voss, Lareb S.N. Dean, Matthew Loxham, Agnes W. Boots, Suzanne M. Cloonan, Catherine M. Greene, Irene H. Heijink, Audrey Joannes, Arnaud A. Mailleux, Nahal Mansouri, Niki L. Reynaert, Anne M. van der Does, Darcy E. Wagner, Niki Ubags
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
In this review, the Basic and Translational Science Assembly of the European Respiratory Society provides an overview of the 2022 International Congress highlights. We discuss the consequences of respiratory events from birth until old age regarding
Externí odkaz:
https://doaj.org/article/0f55052858ca47dfa7980cee3f5d1a8d
Autor:
Mugdha M. Joglekar, Mehmet Nizamoglu, YiWen Fan, Sai Sneha Priya Nemani, Markus Weckmann, Simon D. Pouwels, Irene H. Heijink, Barbro N. Melgert, Janesh Pillay, Janette K. Burgess
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Environmental insults including respiratory infections, in combination with genetic predisposition, may lead to lung diseases such as chronic obstructive pulmonary disease, lung fibrosis, asthma, and acute respiratory distress syndrome. Common charac
Externí odkaz:
https://doaj.org/article/3b38719d4aa64837970662ab2691d344
Autor:
Mahyar Aghapour, Niki D. Ubags, Dunja Bruder, Pieter S. Hiemstra, Venkataramana Sidhaye, Fariba Rezaee, Irene H. Heijink
Publikováno v:
European Respiratory Review, Vol 31, Iss 163 (2022)
Chronic exposure to environmental pollutants is a major contributor to the development and progression of obstructive airway diseases, including asthma and COPD. Understanding the mechanisms underlying the development of obstructive lung diseases upo
Externí odkaz:
https://doaj.org/article/aa1cc6d9c1b34931a9ccab02e3024466
Autor:
Qing Chen, Kingsley Okechukwu Nwozor, Maarten van den Berge, Dirk-Jan Slebos, Alen Faiz, Marnix R. Jonker, H. Marike Boezen, Irene H. Heijink, Maaike de Vries
Publikováno v:
Cells, Vol 11, Iss 21, p 3423 (2022)
Cigarette smoking causes hypomethylation of the gene Aryl Hydrocarbon Receptor Repressor (AHRR), which regulates detoxification and oxidative stress-responses. We investigated whether AHRR DNA methylation is related to chronic obstructive pulmonary d
Externí odkaz:
https://doaj.org/article/8bd946d3f36e4d89bc588c6f8a00ad14
Autor:
Virinchi N. S. Kuchibhotla, Malcolm R. Starkey, Andrew T. Reid, Irene H. Heijink, Martijn C. Nawijn, Philip M. Hansbro, Darryl A. Knight
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Excessive mucus production is a major feature of allergic asthma. Disruption of epithelial junctions by allergens such as house dust mite (HDM) results in the activation of β-catenin signaling, which has been reported to stimulate goblet cell differ
Externí odkaz:
https://doaj.org/article/62d8aebb14634def98e262b080187297