Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Irene Gutierrez Perez"'
Autor:
Irene Gutierrez-Perez, M. Jordan Rowley, Xiaowen Lyu, Viviana Valadez-Graham, Diana M. Vallejo, Esther Ballesta-Illan, Jose P. Lopez-Atalaya, Isaac Kremsky, Esther Caparros, Victor G. Corces, Maria Dominguez
Publikováno v:
Cell Reports, Vol 28, Iss 10, Pp 2715-2727.e5 (2019)
Summary: Evidence suggests that Polycomb (Pc) is present at chromatin loop anchors in Drosophila. Pc is recruited to DNA through interactions with the GAGA binding factors GAF and Pipsqueak (Psq). Using HiChIP in Drosophila cells, we find that the ps
Externí odkaz:
https://doaj.org/article/b1134bcf5a3d40e694e695a94bf900ba
Autor:
Efthymia, Kokkinou, Ram Vinay, Pandey, Luca, Mazzurana, Irene, Gutierrez-Perez, Christopher Andrew, Tibbitt, Whitney, Weigel, Tea, Soini, Anna, Carrasco, Anna, Rao, Maho, Nagasawa, Suzanne M, Bal, Mattias, Jangard, Danielle, Friberg, Ulrik, Lindforss, Caroline, Nordenvall, Malin, Ljunggren, Staffan, Haapaniemi, Åsa V, Keita, Johan, Söderholm, Charlotte, Hedin, Hergen, Spits, Yenan T, Bryceson, Jenny, Mjösberg
Publikováno v:
Science immunology. 7(70)
Innate lymphoid cells (ILCs) are highly plastic and predominantly mucosal tissue-resident cells that contribute to both homeostasis and inflammation depending on the microenvironment. The discovery of naïve-like ILCs suggests an ILC differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0bcc42983c0abd3d073ab1175f096ea
https://pubmed.ncbi.nlm.nih.gov/35427178
https://pubmed.ncbi.nlm.nih.gov/35427178
Autor:
Efthymia Kokkinou, Ram Vinay Pandey, Luca Mazzurana, Irene Gutierrez-Perez, Christopher Andrew Tibbitt, Whitney Weigel, Tea Soini, Anna Carrasco, Anna Rao, Maho Nagasawa, Suzanne M. Bal, Mattias Jangard, Danielle Friberg, Ulrik Lindforss, Caroline Nordenvall, Malin Ljunggren, Staffan Haapaniemi, Åsa V. Keita, Johan Söderholm, Charlotte Hedin, Hergen Spits, Yenan T. Bryceson, Jenny Mjösberg
Publikováno v:
Science immunology, 7(70):abj8301. American Association for the Advancement of Science
Innate lymphoid cells (ILCs) are highly plastic and predominantly mucosal tissue-resident cells that contribute to both homeostasis and inflammation depending on the microenvironment. The discovery of naïve-like ILCs suggests an ILC differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e289ea786a897155a6f9ad0211e77ed5
https://doi.org/10.1126/sciimmunol.abj8301
https://doi.org/10.1126/sciimmunol.abj8301
Autor:
Irene Gutierrez-Perez, Joost Van Ham, Valentin Aranha, Rin Okumura, Elisabeth Waltenberger, Isabella Alt, Claudia Baumgaertler, Maja Stulic, Edgar Petru, Christoph Minichsdorfer, Lukas Hefler, Judith Lafleur, Nikolaus Krall, Thorsten Füreder, Gregory Ian Vladimer, Robert Sehlke, Bojan Vilagos
Publikováno v:
Cancer Research. 82:1893-1893
Background: High unmet need of ovarian cancer (OC) suggests the discovery of new targeted therapeutics is crucial to improve patient prognosis. Unlike artificial model systems such as cell lines, primary cancer samples recapitulate the complexity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ecd89aed68384df1ce12f9e485ddf3e
https://doi.org/10.1158/1538-7445.am2022-1893
https://doi.org/10.1158/1538-7445.am2022-1893
Publikováno v:
PLoS Biology, Vol 11, Iss 5, p e1001554 (2013)
Fine-tuned Notch and Hedgehog signalling pathways via attenuators and dampers have long been recognized as important mechanisms to ensure the proper size and differentiation of many organs and tissues. This notion is further supported by identificati
Externí odkaz:
https://doaj.org/article/14de1cf1f28d4a7393e46f3ec3003f04
Autor:
Florian Rohrer, Nikolaus Krall, Lukas Hefler, Bojan Vilagos, Robert Sehlke, Gregory I. Vladimer, Laudia Hadjari, Diogo Tomaz, Judith Lafleur, Valentin Aranha, Irene Gutierrez Perez, Joost van Ham
Publikováno v:
Cancer Research. 81:1303-1303
Introduction: The paradigm of precision oncology is the selection of optimal therapy for individual patients. However, disease complexity prevents most cases from having a clear correlation between genetics and response, and programs using driver mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6678925f4d933551ea0772c9988819bc
https://doi.org/10.1158/1538-7445.am2021-1303
https://doi.org/10.1158/1538-7445.am2021-1303
Autor:
Xiaowen Lyu, Viviana Valadez-Graham, Isaac Kremsky, M. Jordan Rowley, Victor G. Corces, Maria Dominguez, José P. López-Atalaya, Esther Ballesta-Illan, Esther Caparrós, Irene Gutierrez-Perez, Diana M. Vallejo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Reports, Vol 28, Iss 10, Pp 2715-2727.e5 (2019)
Cell reports
instname
Cell Reports, Vol 28, Iss 10, Pp 2715-2727.e5 (2019)
Cell reports
SUMMARY Evidence suggests that Polycomb (Pc) is present at chromatin loop anchors in Drosophila. Pc is recruited to DNA through interactions with the GAGA binding factors GAF and Pipsqueak (Psq). Using HiChIP in Drosophila cells, we find that the psq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829221d32e6c7484289d8c22d6997e65
http://hdl.handle.net/10261/217800
http://hdl.handle.net/10261/217800
Publikováno v:
Blood. 130:2693-2695
In this issue of Blood, Zhao et al perform single-cell RNA sequencing (scRNA-seq) of bone marrow–derived CD34+ cells from patients with monosomy 7. Identifying cells with chromosome 7 aberrations, they uncover reduced transcription of genes upholdi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d83de15c790925e0f0c20e0893f18b89
https://doi.org/10.1182/blood-2017-11-811935
https://doi.org/10.1182/blood-2017-11-811935
Autor:
Jesús García-Castillo, Vanina Gabriela Da Ros, Santiago Nahuel Villegas, Diana M. Vallejo, Esther Ballesta-Illan, József Mihály, Maria Dominguez, Lucia García-López, Rita Gombos, Irene Gutierrez-Perez
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Cell Reports, Vol 22, Iss 10, Pp 2541-2549 (2018)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Cell Reports, Vol 22, Iss 10, Pp 2541-2549 (2018)
The PI3K/Akt signaling pathway, Notch, and other oncogenes cooperate in the induction of aggressive cancers. Elucidating how the PI3K/Akt pathway facilitates tumorigenesis by other oncogenes may offer opportunities to develop drugs with fewer side ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0b145281983eb48c56791f8bf30f39
http://linkinghub.elsevier.com/retrieve/pii/S2211124718302304
http://linkinghub.elsevier.com/retrieve/pii/S2211124718302304
Autor:
Benedetto Daniele Giaimo, Andrea Nist, Thorsten Stiewe, Gerhard Mittler, Peggy Schwarz, Irene Gutierrez-Perez, Franz Oswald, Diana M. Vallejo, Tilman Borggrefe, Marek Bartkuhn, Kerstin Hein, Susanne Herold, Tobias Zimmermann, Maria Dominguez, Francesca Ferrante
A fundamental as yet incompletely understood feature of Notch signal transduction is a transcriptional shift from repression to activation that depends on chromatin regulation mediated by transcription factor RBP-J and associated cofactors. Incorpora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca72b161ae242d16f1a6178a579bec7
http://hdl.handle.net/10261/308390
http://hdl.handle.net/10261/308390