Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Irene Gall"'
Autor:
Moez Dawood, Shawn Fayer, Sriram Pendyala, Mason Post, Divya Kalra, Karynne Patterson, Eric Venner, Lara A. Muffley, Douglas M. Fowler, Alan F. Rubin, Jennifer E. Posey, Sharon E. Plon, James R. Lupski, Richard A. Gibbs, Lea M. Starita, Carla Daniela Robles-Espinoza, Willow Coyote-Maestas, Irene Gallego Romero
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Multiplexed Assays of Variant Effects (MAVEs) can test all possible single variants in a gene of interest. The resulting saturation-style functional data may help resolve variant classification disparities between populations, esp
Externí odkaz:
https://doaj.org/article/7bb11a609b814018b3cd0242b8aad730
Autor:
Diego González-Morgado, Carlos Mendoza-Aguilo, Irene Gallardo, Alex Lluch, Ignacio Esteban-Feliu
Publikováno v:
JSES International, Vol 8, Iss 6, Pp 1320- (2024)
Externí odkaz:
https://doaj.org/article/6df7c70b9a654117bcab8a581ab63791
Autor:
Irène Gallais Sérézal, Laurie Spehner, Marie Kroemer, Inès Bourezane, Nadine Meaux-Ruault, Clément Prati, Andréa Pastissier, Juliette Lodovichetti, Pierre Tiberghien, François Aubin
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e38043- (2024)
Rituximab (RTX), an anti CD20 monoclonal antibody, is now a gold standard treatment for several auto-immune and chronic inflammatory diseases. Receiving RTX exposes patients to more severe infections as vaccinations become virtually inefficient in te
Externí odkaz:
https://doaj.org/article/becf72c2c0e34155927f52232f2b460c
Autor:
Neke Ibeh, Charles Y. Feigin, Stephen R. Frankenberg, Davis J. McCarthy, Andrew J. Pask, Irene Gallego Romero
Publikováno v:
GigaByte (2024)
Marsupials exhibit distinctive modes of reproduction and early development that set them apart from their eutherian counterparts and render them invaluable for comparative studies. However, marsupial genomic resources still lag far behind those of eu
Externí odkaz:
https://doaj.org/article/291e3e426afa45ddbceae80bbb9976e5
Autor:
Moez Dawood, Shawn Fayer, Mason Post, Divya Kalra, Karynne Patterson, Eric Venner, Lara Muffley, Douglas Fowler, Alan Rubin, Richard Gibbs, Lea Starita, Carla Daniela Robles-Espinoza, Willow Coyote-Maestas, Irene Gallego Romero
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101010- (2024)
Externí odkaz:
https://doaj.org/article/732496a2dfe84733822a484b2c8e62fa
Autor:
Irene Gallego Romero, Amanda J. Lea
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract A long-standing goal of evolutionary biology is to decode how gene regulation contributes to organismal diversity. Doing so is challenging because it is hard to predict function from non-coding sequence and to perform molecular research with
Externí odkaz:
https://doaj.org/article/fb60b230688642549a49607b2899f220
Autor:
Dorothea Lorenz, Burkhard Wiesner, Irene Gall, Michael Beyermann, Pavel I. Nedvetsky, Enno Klussmann, Eduard Stefan, Volker Henn, Christian Hundsrucker, Sebastian Bachmann, Rustam Mollajew, George S. Baillie, Peter Pohl, Eberhard Krause, Miles D. Houslay, Andrew N. Macintyre, Walter Rosenthal, Jens Furkert, Katja Santamaria
Publikováno v:
Journal of the American Society of Nephrology. 18:199-212
The cAMP/protein kinase A (PKA)-dependent insertion of water channel aquaporin-2 (AQP2)-bearing vesicles into the plasma membrane in renal collecting duct principal cells (AQP2 shuttle) constitutes the molecular basis of arginine vasopressin (AVP)-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b68d908a071fd31a0ce534b8426cf3
https://doi.org/10.1681/asn.2006020132
https://doi.org/10.1681/asn.2006020132
Publikováno v:
Journal of Cell Science. 119:3799-3810
The unique N-terminal regions of PDE4 cAMP-specific phosphodiesterases confer interaction with distinct signalling and scaffolding proteins. The PDE4A1 isoform is unique in being entirely membrane associated. Its N-terminal region is formed from two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf2fd04032fe1965a6660457c549acc
https://doi.org/10.1242/jcs.03106
https://doi.org/10.1242/jcs.03106
Autor:
Irene Gall, Richard Graham Knowles, Lachlan Campbell, Thomas M. Houslay, Lee Ann Johnston, York-Fong Cheung, Michael Sullivan, Douglas MacMaster, Robin A. Smith, Derek A. Wallace, Miles D. Houslay, Elaine Huston, Jenni E. Millen
Publikováno v:
Molecular Pharmacology. 67:1920-1934
PDE4A11 is a novel cAMP-specific phosphodiesterase that is conserved in humans, mouse, rat, pig, and bat. Exon-1(4A11) encodes its unique, 81 amino acid N-terminal region. Reverse-transcriptase polymerase chain reaction performed across the splice ju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e2c8498d063bb683d8154599ebccf2
https://doi.org/10.1124/mol.104.009423
https://doi.org/10.1124/mol.104.009423
Autor:
Robert Terry, Morten Praestegaard, Irene Gall, Miles D. Houslay, George S. Baillie, David R. Adams, York Fong Cheung, Elaine Huston
Publikováno v:
Cellular Signalling. 15:955-971
In cells transfected to express wild-type PDE4A4 cAMP phosphodiesterase (PDE), the PDE4 selective inhibitor rolipram caused PDE4A4 to relocalise so as to form accretion foci. This process was followed in detail in living cells using a PDE4A4 chimera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47684844d9956700c7137b5b4999acb
https://doi.org/10.1016/s0898-6568(03)00092-5
https://doi.org/10.1016/s0898-6568(03)00092-5