Tolerability of vortioxetine compared to selective serotonin reuptake inhibitors in older adults with major depressive disorder (VESPA): a randomised, assessor-blinded and statistician-blinded, multicentre, superiority trialResearch in context

Autor: Giovanni Ostuzzi, Chiara Gastaldon, Mauro Tettamanti, Massimo Cartabia, Igor Monti, Andrea Aguglia, Eugenio Aguglia, Francesco Bartoli, Camilla Callegari, Andrea Canozzi, Elvira Anna Carbone, Giuseppe Carrà, Rosangela Caruso, Simone Cavallotti, Stefania Chiappini, Fabrizio Colasante, Beatrice Compri, Armando D'Agostino, Pasquale De Fazio, Renato de Filippis, Matteo Gari, Marta Ielmini, Gianmarco Ingrosso, Silvia Mammarella, Giovanni Martinotti, Alessandro Rodolico, Rita Roncone, Enrico Sterzi, Lorenzo Tarsitani, Elisa Tiberto, Liliana Todini, Francesco Amaddeo, Barbara D'Avanzo, Angelo Barbato, Corrado Barbui, Maria Chiara Alessi, Gabriele Avincola, Bianca Bachi, Gianna Bernasconi, Andrea Birgillito, Emanuele Bisso, Stefano Bonora, Angela Calabrese, Tommaso Callovini, Aurelia Canestro, Salvo Canonico, Chiara Alessandro Capogrosso, Elvira Carbone, Doriana Carosielli, Ivano Caselli, Daniele Cavaleri, Clara Cavallotto, Marco Cesca, Cecilia Chiarenza, Riccardo Matteo Cioni, Sara Coloccini, Marco Cruciata, Claudia Cumerlato, Renato De Filippis, Manuela De Palma, Sasha Del Vecchio, Bianca Della Rocca, Chiara Di Natale, Ettore D'Onofrio, Irene Espa, Giulia Fior, Marta Gancitano, Barbara Giordano, Laura Giusti, Luigi Grassi, Pierluca Guzzi, Celeste Isella, Annamaria Lax, Leonardo Marano, Federico Marconi, Marco Marella, Alessia Metelli, Giulia Michencig, Andrea Miuli, Alessandro Moncada, Pietro Morello, Federico Moretti, Marco Morreale, Alessio Mosca, Christian Nasti, Michela Nosé, Filippo Ogheri, Margherita Oresti, Alessandra Ornaghi, Dario Palpella, Corinna Pancheri, Davide Papola, Silvia Passeri, Mauro Pettorusso, Susanna Piacenti, Irene Pinucci, Valentina Pugliese, Marianna Purgato, Marianna Rania, Federica Robbi, Samantha Romito, Barbara Ronchi, Valentina Roselli, Cristina Segura-Garcia, Maria Salvina Signorelli, Gabriele Simonelli, Antonella Sociali, Serena Sturiale, Antonio Tambelli, Beatrice Todesco, Alice Trabucco, Giulia Turrini, Veronica Villa, Federico Wiedenmann, Luca Zambuto, Elisa Zanini, Chiara Zannini, Luigi Zerbinati

Publikováno v: EClinicalMedicine, Vol 69, Iss , Pp 102491- (2024)

Summary: Background: Major depressive disorder (MDD) is prevalent and disabling among older adults. Standing on its tolerability profile, vortioxetine might be a promising alternative to selective serotonin reuptake inhibitors (SSRIs) in such a vulne

Externí odkaz: https://doaj.org/article/b6d9532a29514d6885cce2880822f39b

Do adolescents and young adults accessing the Emergency Room with substance use receive poor therapeutic indications at discharge? An observational retrospective study

Autor: Alberto Varinelli, Bernardo Dell'Osso, Anna Maria Brambilla, Caterina Viganò, Marian Mora Conde, Irene Espa, Laura Molteni, Rita Cafaro

Publikováno v: International Journal of Clinical Practice. 75

Purpose Emergency rooms (ERs) are usually the first point of contact with mental health services for adolescents with Substance Use Disorders (SUDs). However, only a minority of them receives proper treatment and follow-up indications, increasing the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efbc1981a17272c6942ab0a6d96d4ea
https://doi.org/10.1111/ijcp.14890

Antiviral Potential and Chemical Composition of Wild Baccharis crispa Spreng. Populations (Asteraceae) from Córdoba, Argentina: Perspective on Population Variability

Autor: Giuliana Lingua, Ana Guadalupe Chaves, Juan Javier Aguilar, Florencia Martinez, Tomás Isaac Gomez, Kevin Alen Rucci, Lorena E. Torres, Carmen Ancín-Azpilicueta, Irene Esparza, Nerea Jiménez-Moreno, Marta Contigiani, Susana Nuñez Montoya, Brenda S. Konigheim

Publikováno v: Plants, Vol 13, Iss 21, p 3077 (2024)

Medicinal plants have been explored worldwide as potential alternatives for the prevention and treatment of different diseases, including viral infections. Baccharis crispa Spreng. (Asteraceae) is a native medicinal species widely used in South Ameri

Externí odkaz: https://doaj.org/article/b760db8ee4e24e328c2907009bf71016

Evaluation of grape stems and grape stem extracts for sulfur dioxide replacement during grape wine production

Autor: Danielle P. Nogueira, Nerea Jiménez-Moreno, Irene Esparza, Jose Antonio Moler, Pedro Ferreira-Santos, Ana Sagües, José António Teixeira, Carmen Ancín-Azpilicueta

Publikováno v: Current Research in Food Science, Vol 6, Iss , Pp 100453- (2023)

Sulfur dioxide (SO2), the main preservative in wine, may affect the sensory properties of the wines, as well as cause allergic reactions and headaches in sensitive people. The aim of this work was to evaluate the replacement of SO2 in Tempranillo win

Externí odkaz: https://doaj.org/article/06de59f8818e44daafefccbdadd725f8

Stability and Bioaccessibility of Phenolic Compounds in Rosehip Extracts during In Vitro Digestion

Autor: Isabel Odriozola-Serrano, Danielle P. Nogueira, Irene Esparza, Ana A. Vaz, Nerea Jiménez-Moreno, Olga Martín-Belloso, Carmen Ancín-Azpilicueta

Publikováno v: Antioxidants, Vol 12, Iss 5, p 1035 (2023)

Rosehips, particularly dog rose fruits (Rosa canina L.), are a great source of antioxidant compounds, mainly phenolics. However, their health benefits directly depend on the bioaccessibility of these compounds affected by gastrointestinal digestion.

Externí odkaz: https://doaj.org/article/73aca0a457fc4181b3ea8637e676752e