Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Irene E. Zohn"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Many studies support the link between parental obesity and the predisposition to develop adult-onset metabolic syndromes that include obesity, high blood pressure, dyslipidemia, insulin resistance, and diabetes in the offspring. As the prevalence of
Externí odkaz:
https://doaj.org/article/798a2d44efd541d095829e0b49bb4c6f
Autor:
Lauren Welby, Hailey Caudill, Gelila Yitsege, Ali Hamad, Filiz Bunyak, Irene E. Zohn, Thomas Maynard, Anthony-Samuel LaMantia, David Mendelowitz, Teresa E. Lever
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Disrupted development of oropharyngeal structures as well as cranial nerve and brainstem circuits may lead to feeding and swallowing difficulties in children with 22q11. 2 deletion syndrome (22q11DS). We previously demonstrated aspiration-based dysph
Externí odkaz:
https://doaj.org/article/7a26bac5f9b54f2fa121e8bc624dbce1
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 1 (2019)
The development of the aortic arch is a complex process that involves remodeling of the bilaterally symmetrical pharyngeal arch arteries (PAAs) into the mature asymmetric aortic arch. Retinoic acid signaling is a key regulator of this process by dire
Externí odkaz:
https://doaj.org/article/f16d777b16254fa69d0b0a1b290402cf
Autor:
Beverly A. Karpinski, Thomas M. Maynard, Matthew S. Fralish, Samer Nuwayhid, Irene E. Zohn, Sally A. Moody, Anthony-S. LaMantia
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 2, Pp 245-257 (2014)
We assessed feeding-related developmental anomalies in the LgDel mouse model of chromosome 22q11 deletion syndrome (22q11DS), a common developmental disorder that frequently includes perinatal dysphagia – debilitating feeding, swallowing and nutrit
Externí odkaz:
https://doaj.org/article/3d1c470eb871483a8acf2cece0a1d79e
Publikováno v:
Am J Med Genet A
Aldehyde Dehydrogenase 1, Family Member A2 (ALDH1A2) is essential for the synthesis of retinoic acid from vitamin A. Studies in model organisms demonstrate a critical role for ALDH1A2 in embryonic development, yet few pathogenic variants are linked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d60363d5d4bf01b69c67274652fd144
https://europepmc.org/articles/PMC9805811/
https://europepmc.org/articles/PMC9805811/
Autor:
Kelsey F Sugrue, Irene E Zohn
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171180 (2017)
Leftward fluid flow in the mouse node is generated by cilia and is critical for initiating asymmetry of the left-right axis. Coiled-coil domain containing-40 (Ccdc40) plays an evolutionarily conserved role in the assembly of motile cilia and establis
Externí odkaz:
https://doaj.org/article/a52e7ef1ba0f4526ac764adae9732fee
Autor:
Anthony-Samuel LaMantia, Gelila Yitsege, Gabor Banyai, Irene E. Zohn, Elizabeth M. Paronett, Beverly A. Karpinski, Thomas M. Maynard, Julia A. Sabatino, Kelsey F. Sugrue, Bethany A. Stokes
Publikováno v:
Birth Defects Research
Background Vitamin A regulates patterning of the pharyngeal arches, cranial nerves, and hindbrain that are essential for feeding and swallowing. In the LgDel mouse model of 22q11.2 deletion syndrome (22q11DS), morphogenesis of multiple structures inv
Autor:
Irene E. Zohn
Publikováno v:
genesis. 59
Autor:
Irene E, Zohn
Publikováno v:
Advances in experimental medicine and biology. 1236
During embryonic development, the central nervous system forms as the neural plate and then rolls into a tube in a complex morphogenetic process known as neurulation. Neural tube defects (NTDs) occur when neurulation fails and are among the most comm
Suckling, Feeding, and Swallowing: Behaviors, Circuits, and Targets for Neurodevelopmental Pathology
Publikováno v:
Annu Rev Neurosci
All mammals must suckle and swallow at birth, and subsequently chew and swallow solid foods, for optimal growth and health. These initially innate behaviors depend critically upon coordinated development of the mouth, tongue, pharynx, and larynx as w