Výsledky vyhledávání - "Irene Dougherty"

Biallelic variants in RNU12 cause CDAGS syndrome

Autor: Mirna Toledo-Bahena, Alan D. Irvine, Nnenna G. Agim, Richard C. Wang, Donald A. Glass, Irene Dougherty, Mohammed Kanchwala, Chao Xing, Monique G. Kumar, An Tran, Marwan Shinawi, David R. Berk, Andrea Tovar-Garza, Jonathan J. Rios, Christy Purnadi, Tommy Hyatt

Publikováno v: Human mutationREFERENCES. 42(8)

CDAGS Syndrome is a rare congenital disorder characterized by Craniosynostosis, Delayed closure of the fontanelles, cranial defects, clavicular hypoplasia, Anal and Genitourinary malformations, and Skin manifestations. We performed whole exome and Sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0452ddbff2f0a772e2edb9996f4ddfd
https://pubmed.ncbi.nlm.nih.gov/34085356

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Inhibition of the elicitation phase of contact hypersensitivity by thymidine dinucleotides is in part mediated by increased expression of interleukin-10 in human keratinocytes

Autor: Irene Dougherty, Suraj S. Venna, Mark S. Eller, Ponciano D. Cruz, Barbara A. Gilchrest, William W. Cruikshank, Clara Curiel-Lewandrowski

Publikováno v: Experimental Dermatology. 12:145-152

The production of immunomodulatory cytokines such as interleukin-10 (IL-10) from keratinocytes and other target cells in the skin plays a crucial role in UV-induced immunosuppression. Substantial evidence supports an association between DNA damage an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b19d836afa5b9a19af2f077e9fc490c
https://doi.org/10.1034/j.1600-0625.2003.120204.x

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Genomic scale analysis of the human keratinocyte response to broad-band ultraviolet-B irradiation

Autor: Ponciano D. Cruz, Kiyoshi Ariizumi, Irene Dougherty, Joe Takao

Publikováno v: Photodermatology, Photoimmunology & Photomedicine. 18:5-13

Ultraviolet B (UVB) radiation is an important inducer of many biologic changes in skin, of which keratinocytes are a key target. To gain better insight into changes in gene expression generated in the early phase after UVB exposure, we used complemen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8eb746e9475c2459e9fcc6fb54dfefbe
https://doi.org/10.1034/j.1600-0781.2002.180102.x

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Thymidine Dinucleotides Inhibit Contact Hypersensitivity and Activate the Gene for Tumor Necrosis Factor α11The authors did not submit a completed declaration of conflict of interest form as requested by the JID’s ‘‘Information for authors’’

Autor: Mina Yaar, Mark S. Eller, Irene Dougherty, Barbara A. Gilchrest, Ponciano D. Cruz, Michelle J. Gleason, Martin Leverkus

Publikováno v: Journal of Investigative Dermatology. 114:253-258

DNA is a target for ultraviolet-B-induced inhibition of contact hypersensitivity, and small DNA fragments such as thymidine dinucleotides (pTpT) can simulate several ultraviolet-induced effects. To determine whether pTpT mimics the suppressive influe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c136aa236967ff39decf7467d109cf
https://doi.org/10.1046/j.1523-1747.2000.00866.x

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Interleukin-15 expression by human endothelial cells: up-regulation by ultraviolet B and psoralen plus ultraviolet A treatment

Autor: M. J. McGuire, Mansour Mohamadzadeh, Ponciano D. Cruz, Irene Dougherty

Publikováno v: Photodermatology, Photoimmunology & Photomedicine. 12:17-21

The purposes of the present study were to determine whether endothelial cells express IL-15 and to evaluate effects of ultraviolet B (UVB) and 8-methoxypsoralens plus UVA (PUVA) on such expression. Cultured human endothelial cells derived from dermis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5afbf5ef6e2c8e294baa97cd5a3bf1b
https://doi.org/10.1111/j.1600-0781.1996.tb00238.x

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Expression of the Tumor Necrosis Factor Gene by Dermal Fibroblasts in Response to Ultraviolet Irradiation or Lipopolysaccharide

Autor: Bruce Beutler, Patricia A. Thompson, Sylvie De Kossodo, Irene Dougherty, Maria Silva-Valdez, Ponciano D. Cruz

Publikováno v: Journal of Investigative Dermatology. 104(3):318-322

To examine the effects of different wavelengths of ultraviolet (UV) radiation on tumor necrosis factor (TNF) production, we took advantage of mice carrying a chloramphenicol acetyl transferase (CAT) reporter transgene bearing the entire TNF promoter

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