Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Irene Dell'Anno"'
Autor:
Irene Dell’Anno, Federica Morani, Simone Patergnani, Antonio Daga, Paolo Pinton, Carlotta Giorgi, Luciano Mutti, Federica Gemignani, Stefano Landi
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Malignant Pleural Mesothelioma (MPM) is a rare malignancy with a poor prognosis. Current therapies are unsatisfactory and novel cures are urgently needed. In a previous drug screening, we identified thonzonium bromide (TB) as one
Externí odkaz:
https://doaj.org/article/9e39a12c4d36447294cc9a0d363b6fd7
Autor:
Roberto Silvestri, Lorenzo Zallocco, Alda Corrado, Maurizio Ronci, Romina Aceto, Benedetta Ricci, Monica Cipollini, Irene Dell’Anno, Chiara De Simone, Giuseppina De Marco, Eleonora Ferrarini, Daniela Beghelli, Maria Rosa Mazzoni, Antonio Lucacchini, Federica Gemignani, Laura Giusti, Stefano Landi
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionThe single nucleotide polymorphism (SNP) rs4644 at codon 64 of galectin-3 (gal-3, gene name: LGALS3), specifying the variant proline (P64) to histidine (H64), is known to affect the protein’s functions and has been associated with the r
Externí odkaz:
https://doaj.org/article/dfc7c86e983b4d86a4485a26ef186a0d
Autor:
Irene Dell’Anno, Elisa Barone, Luciano Mutti, Doris M. Rassl, Stefan J. Marciniak, Roberto Silvestri, Stefano Landi, Federica Gemignani
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-7 (2020)
Abstract Background Malignant pleural mesothelioma (MPM) is an aggressive neoplasm of the pleura, mainly related to asbestos exposure. As in other solid tumors, malignant cells exhibit high glucose uptake and glycolytic rates with increased lactic ac
Externí odkaz:
https://doaj.org/article/45e9b03941324c8495c5c5c5383d16e1
Autor:
Roberto Silvestri, Perla Pucci, Chiara De Santi, Irene Dell’Anno, Simona Miglietta, Alda Corrado, Vanessa Nicolí, Daniela Marolda, Monica Cipollini, Enrica Pellegrino, Monica Evangelista, Alessandra Bonotti, Rudy Foddis, Alfonso Cristaudo, Stefano Landi, Federica Gemignani
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Soluble mesothelin-related peptide (SMRP) is a promising biomarker for malignant pleural mesothelioma (MPM), but several confounding factors can reduce SMRP-based test’s accuracy. The identification of these confounders could improve the diagnostic
Externí odkaz:
https://doaj.org/article/fa1be331a6b945f292d0a23b17377ebb
Autor:
Irene Dell’Anno, Marcella Barbarino, Elisa Barone, Antonio Giordano, Luca Luzzi, Maria Bottaro, Loredana Migliore, Silvia Agostini, Alessandra Melani, Ombretta Melaiu, Calogerina Catalano, Monica Cipollini, Roberto Silvestri, Alda Corrado, Federica Gemignani, Stefano Landi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 4856 (2020)
For malignant pleural mesothelioma (MPM) novel therapeutic strategies are urgently needed. In a previous study, we identified 51 putative cancer genes over-expressed in MPM tissues and cell lines. Here, we deepened the study on nine of them (ASS1, EI
Externí odkaz:
https://doaj.org/article/2d29070c916e4f4084c7c9a969844b5d
Autor:
Irene, Dell'Anno, Silvia, Calabria, Letizia, Dondi, Giulia, Ronconi, Leonardo, Dondi, Alice, Addesi, Antonella, Pedrini, Immacolata, Esposito, Aldo Pietro, Maggioni, Nello, Martini, Carlo, Piccinni
Publikováno v:
Recenti progressi in medicina. 114(1)
The adoption of a Care Pathway (CP) allows the healthcare management of patients suffering from high-epidemiological impact chronic diseases. The continuity of care of these patients is one of the main purposes of the community-based healthcare refor
Autor:
Irene Dell’Anno, Alessandra Melani, Sarah A. Martin, Marcella Barbarino, Roberto Silvestri, Monica Cipollini, Antonio Giordano, Luciano Mutti, Andrea Nicolini, Luca Luzzi, Raffaele Aiello, Federica Gemignani, Stefano Landi
Publikováno v:
Cancers; Volume 14; Issue 10; Pages: 2527
The lack of effective therapies remains one of the main challenges for malignant pleural mesothelioma (MPM). In this perspective, drug repositioning could accelerate the identification of novel treatments. We screened 1170 FDA-approved drugs on a SV4
Autor:
Alda Corrado, Roberto Giovannoni, Laura Poliseno, Marianna Vitiello, Irene Dell’Anno, Simona Miglietta, Romina Aceto, Federica Gemignani, Monica Evangelista, Roberto Silvestri, Monica Cipollini, Lorenzo Zallocco, Rossella Elisei, Laura Giusti, Benedetta Ricci, Cristina Romei, Sonia Garritano, Stefano Landi
Background: Galectin-3 (LGALS3) is an important glycoprotein involved in the malignant transformation of thyrocytes acting in the extracellular matrix, cytoplasm, and nucleus where it regulates TTF...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3897ea8676f7b5d18c3e5ee873df8128
https://hdl.handle.net/11568/1078395
https://hdl.handle.net/11568/1078395
Autor:
Federica Gemignani, Alda Corrado, Elisa Paolicchi, Antonio Giordano, Roberto Silvestri, Sarah A. Martin, Alessandra Melani, Maria Bottaro, Luca Luzzi, Marcella Barbarino, Ombretta Melaiu, Monica Cipollini, Stefano Landi, Irene Dell’Anno
Publikováno v:
Investigational New Drugs
SummaryObjectives Malignant pleural mesothelioma (MPM) is an occupational disease mainly due to asbestos exposure. Effective therapies for MPM are lacking, making this tumour type a fatal disease. Materials and Methods In order to meet this need and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd08c66ec5519c3f341c3eddb6df2592
http://hdl.handle.net/2108/305989
http://hdl.handle.net/2108/305989
Autor:
Stefano Landi, Alda Corrado, Alessandra Melani, Maria Bottaro, Loredana Migliore, Roberto Silvestri, Ombretta Melaiu, Elisa Barone, Silvia Agostini, Monica Cipollini, Luca Luzzi, Antonio Giordano, Irene Dell’Anno, Federica Gemignani, Calogerina Catalano, Marcella Barbarino
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 4856, p 4856 (2020)
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 4856, p 4856 (2020)
For malignant pleural mesothelioma (MPM) novel therapeutic strategies are urgently needed. In a previous study, we identified 51 putative cancer genes over-expressed in MPM tissues and cell lines. Here, we deepened the study on nine of them (ASS1, EI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7091a0e46943b743b9ad91c9c0cde5af
http://hdl.handle.net/2108/305968
http://hdl.handle.net/2108/305968