Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Irene D Román"'
Autor:
Luis G. Guijarro, David Cano-Martínez, M.Val Toledo-Lobo, Patricia Sanmartín Salinas, María Chaparro, Ana M. Gómez-Lahoz, Sofía Zoullas, Rosa Rodríguez-Torres, Irene D. Román, Laura Sebastián Monasor, Lidia Ruiz-Llorente, María del Carmen Boyano-Adánez, Iván Guerra, Marisa Iborra, José Luis Cabriada, Luis Bujanda, Carlos Taxonera, Valle García-Sánchez, Ignacio Marín-Jiménez, Manuel Barreiro-de Acosta, Isabel Vera, María Dolores Martín-Arranz, Francisco Mesonero, Laura Sempere, Fernando Gomollón, Joaquín Hinojosa, Melchor Alvarez-Mon, Javier P. Gisbert, Miguel A. Ortega, Borja Hernández-Breijo, on behalf of the PREDICROHN study group from GETECCU
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112239- (2021)
Inflammatory bowel diseases (IBD), represented by ulcerative colitis (UC) and Crohn's disease (CD), are characterized by chronic inflammation of the gastrointestinal tract, what leads to diarrhea, malnutrition, and weight loss. Depression of the grow
Externí odkaz:
https://doaj.org/article/07a4ccf32ca74a43a9db582d7fa13f0a
Autor:
Patricia Sanmartín-Salinas, Silvia Sacristán, Jorge Monserrat, Maria V.T. Lobo, María Dolores Fernández-Moreno, Luis G. Guijarro, Borja Hernández-Breijo, Javier P. Gisbert, Irene D Román, D. Cano-Martínez
Publikováno v:
Biomarkers. 22:133-144
Our purpose was to study the molecular basis of infliximab (IFX) effect on colon mucosa in a colitis model and to identify new biomarkers of mucosal healing.Healthy rats and rats which were subjected to experimental colitis induced by dextran sulfate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d4a4b85daa17989ae9a30095a907f4
https://doi.org/10.1080/1354750x.2016.1252950
https://doi.org/10.1080/1354750x.2016.1252950
Autor:
Águeda González-Rodríguez, Ángela M. Valverde, Borja Hernández-Breijo, Ma Dolores Fernández-Moreno, Jorge Monserrat, Javier P. Gisbert, Irene D Román, M Val T Lobo, Luis G. Guijarro
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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instname
et al.
Hepatoblastoma is a primary liver cancer that affects children, due to the sensitivity of this tumor to insulin-like growth factor 1 (IGF-1). In this paper we show that azathioprine (AZA) is capable of inhibiting IGF1-mediated signaling c
Hepatoblastoma is a primary liver cancer that affects children, due to the sensitivity of this tumor to insulin-like growth factor 1 (IGF-1). In this paper we show that azathioprine (AZA) is capable of inhibiting IGF1-mediated signaling c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5e212164ff8512b38c44246b09af34
https://doi.org/10.1016/j.taap.2013.07.024
https://doi.org/10.1016/j.taap.2013.07.024
Autor:
Irene D Román, Luis G. Guijarro, Ma Dolores Fernández-Moreno, Borja Hernández-Breijo, Javier P. Gisbert
Publikováno v:
Current Drug Metabolism. 13:1267-1276
Thiopurines (azathioprine, 6-mercaptopurine and 6-thioguanine), are drugs useful in the treatment of leukemia, autoimmune diseases, as well as in organ transplantation. After many years of use is still not well understood their mode of action. Recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffbaa03d401c53874fb589cf86b0331
https://doi.org/10.2174/138920012803341366
https://doi.org/10.2174/138920012803341366
Autor:
Oscar Escribano, Jorge Monserrat, Irene D Román, María G. Sánchez, Verónica Sánchez-Alonso, María Dolores Fernández-Moreno, E.P. Cuevas, Borja Hernández-Breijo, Antonio Chiloeches, Javier Martínez-Botas, Luis G. Guijarro
Publikováno v:
Journal of Cellular Biochemistry. 108:1292-1301
Insulin receptor substrate-4 (IRS-4) transmits signals from the insulin-like growth factor receptor (IGF-IR) and the insulin receptor (IR) to the PI3K/AKT and the ERK1/2 pathways. IRS-4 expression increases dramatically after partial hepatectomy and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d0ea368ef0c51a03dfd925d7d80f4d
https://doi.org/10.1002/jcb.22359
https://doi.org/10.1002/jcb.22359
Autor:
D. Cano-Martínez, Irene Moreno-Villena, Irene D Román, Alberto Paradela, Patricia Sanmartín-Salinas, Jorge Monserrat, Óscar Pastor, M Val T Lobo, Borja Hernández-Breijo, Ma Dolores Fernández-Moreno, Luis G. Guijarro, Javier P. Gisbert
Publikováno v:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 19(8)
Infliximab (IFX) is widely used in ulcerative colitis and in Crohn’s disease treatment. Both diseases are characterised by increased oxidative stress, which may affect albumin oxidation. In order to test this hypothesis, the effect of IFX on coliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ce0515c719643e78c00c511e4a2758
https://pubmed.ncbi.nlm.nih.gov/25382460
https://pubmed.ncbi.nlm.nih.gov/25382460
Autor:
Carlos Cara, Luis Gonzales Guijarro, Oscar Escribano, Jesús A. Fueyo, Irene D Román, María Dolores Fernández-Moreno, César Menor
Publikováno v:
Therapeutic Drug Monitoring. 23:536-541
The current article describes a new assay to measure thiopurine methyltransferase (TPMT) activity from red blood cells. This method is based on the measurement of the reaction product 6-methylmercaptopurine (6-MMP) by high-performance liquid chromato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503c403990729a3a7de6d309749d1950
https://doi.org/10.1097/00007691-200110000-00007
https://doi.org/10.1097/00007691-200110000-00007
Autor:
Irene D Román, Diana Vara, Borja Hernández-Breijo, Sara Ramírez-Rubio, Javier P. Gisbert, Inés Díaz-Laviada, Luis G. Guijarro, M. Dolores Fernández-Moreno, E.P. Cuevas, Jorge Monserrat
Publikováno v:
World journal of gastroenterology. 17(34)
AIM: To evaluate the efficacy and the safety of azathioprine (AZA) and buthionine sulfoximine (BSO) by localized application into HepG2 tumor in vivo. METHODS: Different hepatoma and colon carcinoma cell lines (HepG2, HuH7, Chang liver, LoVo, RKO, SW
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998cf5760d143d8d11eb9705f934f797
https://pubmed.ncbi.nlm.nih.gov/22025878
https://pubmed.ncbi.nlm.nih.gov/22025878
Autor:
María Dolores Fernández-Moreno, Oscar Escribano, Antonio Chiloeches, E.P. Cuevas, Luis G. Guijarro, Sara Ramirez Rubio, Irene D Román
Publikováno v:
Journal of hepatology. 46(6)
Backgrounds/Aims Insulin receptor substrate-4 (IRS-4) is a scaffold protein that mediates the actions of insulin-like growth factor-I (IGF-I). Its expression increases dramatically after partial hepatectomy (a liver regeneration model). Herein, we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be409c0ae7deb80f59bd0d9dbcfa58c
https://pubmed.ncbi.nlm.nih.gov/17408801
https://pubmed.ncbi.nlm.nih.gov/17408801
Autor:
Irene D Román, Jesús A. Fueyo, Oscar Escribano, María Dolores Fernández-Moreno, César Menor, Rosa María Ropero, Luis G. Guijarro, Inés Díaz-Laviada, José A. Zueco
Publikováno v:
Hepatology (Baltimore, Md.). 37(6)
This study was designed to characterize insulin receptor substrate-4 (IRS-4) in isolated rat hepatocytes and to examine its role in liver regeneration. Subcellular fractionation revealed that 85% of IRS-4 is located at isolated hepatocyte plasma memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfc082eeae0763823fb81bde105ed8d
https://pubmed.ncbi.nlm.nih.gov/12774026
https://pubmed.ncbi.nlm.nih.gov/12774026