Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Irene Chiolo"'
Autor:
Maria Dilia Palumbieri, Chiara Merigliano, Daniel González-Acosta, Danina Kuster, Jana Krietsch, Henriette Stoy, Thomas von Känel, Svenja Ulferts, Bettina Welter, Joël Frey, Cyril Doerdelmann, Andrea Sanchi, Robert Grosse, Irene Chiolo, Massimo Lopes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the context of nuclear organization is currently unknown. Using nuclear actin probes in
Externí odkaz:
https://doaj.org/article/9ce0187fdcd948fb8a159bba559a5fee
AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody.
Autor:
Chiara Merigliano, Romina Burla, Mattia La Torre, Simona Del Giudice, Hsiangling Teo, Chong Wai Liew, Alexandre Chojnowski, Wah Ing Goh, Yolanda Olmos, Klizia Maccaroni, Maria Giubettini, Irene Chiolo, Jeremy G Carlton, Domenico Raimondo, Fiammetta Vernì, Colin L Stewart, Daniela Rhodes, Graham D Wright, Brian E Burke, Isabella Saggio
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009757 (2021)
To complete mitosis, the bridge that links the two daughter cells needs to be cleaved. This step is carried out by the endosomal sorting complex required for transport (ESCRT) machinery. AKTIP, a protein discovered to be associated with telomeres and
Externí odkaz:
https://doaj.org/article/bc66149e25c047faa2127e3e143af22e
Publikováno v:
Genes, Vol 13, Iss 3, p 529 (2022)
Pericentromeric heterochromatin is mostly composed of repetitive DNA sequences prone to aberrant recombination. Cells have developed highly specialized mechanisms to enable ‘safe’ homologous recombination (HR) repair while preventing aberrant rec
Externí odkaz:
https://doaj.org/article/d9b93240d3fa40d39bce91d9c7fed9ff
Autor:
Judith Miné-Hattab, Irene Chiolo
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
A number of studies across different model systems revealed that chromatin undergoes significant changes in dynamics in response to DNA damage. These include local motion changes at damage sites, increased nuclear exploration of both damaged and unda
Externí odkaz:
https://doaj.org/article/8f261851aee54f0cbfba97b06e8b2c2c
Autor:
Qingjiao Li, Harianto Tjong, Xiao Li, Ke Gong, Xianghong Jasmine Zhou, Irene Chiolo, Frank Alber
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-22 (2017)
Abstract Background Genome structures are dynamic and non-randomly organized in the nucleus of higher eukaryotes. To maximize the accuracy and coverage of three-dimensional genome structural models, it is important to integrate all available sources
Externí odkaz:
https://doaj.org/article/ec2027705efc4244b7b48e749435ee3c
Autor:
Maria Dilia Palumbieri, Chiara Merigliano, Daniel González Acosta, Thomas von Känel, Bettina Welter, Henriette Stoy, Jana Krietsch, Svenja Ulferts, Andrea Sanchi, Robert Grosse, Irene Chiolo, Massimo Lopes
Publikováno v:
bioRxiv
Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the context of nuclear organization is currently unknown. Using nuclear actin probes in living an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859d8a9fd3cbd8f88f59be0633e641af
https://doi.org/10.1101/2023.03.24.534097
https://doi.org/10.1101/2023.03.24.534097
Autor:
Jacob M. Miller, Sydney Prange, Huanding Ji, Alesandra R. Rau, Avi Patel, Nadejda L. Butova, Avery Lutter, Helen Chung, Chiara Merigliano, Chetan C. Rawal, Terrence Hanscom, Mitch McVey, Irene Chiolo
Pericentromeric heterochromatin is highly enriched for repetitive sequences prone to aberrant recombination. Previous studies showed that homologous recombination (HR) repair is uniquely regulated in this domain to enable ‘safe’ repair while prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf968c41a360d3e2a4c094341c382ce1
https://doi.org/10.1101/2023.03.03.531058
https://doi.org/10.1101/2023.03.03.531058
Autor:
Irene Chiolo, Chiara Merigliano
Publikováno v:
Curr Opin Genet Dev
Studies across different organisms show that nuclear architecture and dynamics play central roles in different aspects of homologous recombination (HR) repair. Here we review the most recent discoveries in this field, ranging from directed motions me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc031a9609f28f8a12e124e670dad622
https://europepmc.org/articles/PMC9388045/
https://europepmc.org/articles/PMC9388045/
Autor:
Chiara Merigliano, Irene Chiolo
Studies across different organisms show that nuclear architecture and dynamics play central roles in different aspects of homologous recombination (HR) repair. Here we review the most recent discoveries in this field, ranging from directed motions me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfb31dc4af049fa2a7ebe24e8600b6ff
https://doi.org/10.31219/osf.io/3fn5q
https://doi.org/10.31219/osf.io/3fn5q
Autor:
Chong Wai Liew, Mattia La Torre, Colin L. Stewart, Brian Burke, Yolanda Olmos, Isabella Saggio, Chiara Merigliano, Domenico Raimondo, Fiammetta Vernì, Daniela Rhodes, Irene Chiolo, Jeremy G. Carlton, Graham D. Wright, Hsiang Ling Teo, Simona Del Giudice, Alexandre Chojnowski, Wah Ing Goh, Romina Burla
To complete mitosis, the intercellular bridge that links daughter cells needs to be cleaved. This abscission step is carried out by the sequential recruitment of ESCRT proteins at the midbody. We report here that a new factor, named AKTIP, works in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd9e21723ebc00fa9347ade28df87fe
https://doi.org/10.1101/2020.01.19.911891
https://doi.org/10.1101/2020.01.19.911891