Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Irene Beate Sørvik"'
Autor:
Eirik Johansson Solum, Nils Anders Labba, Ragnhild E. Paulsen, Trond Vidar Hansen, Irene Beate Sørvik
Publikováno v:
Free radical research. 52(2)
Oestrogens with no or reduced oestrogen receptor (ER) binding properties are reported to have neuroprotective functions. However, we have previously shown that the hormonally inactive isomer of 17β-estradiol (17β-E), 17α-estradiol (17α-E), down-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb74b93b21fc3b7303315bcfb784285
https://pubmed.ncbi.nlm.nih.gov/29405079
https://pubmed.ncbi.nlm.nih.gov/29405079
Publikováno v:
Biochemical and biophysical research communications. 490(3)
17α-estradiol is a hormonally inactive isomer of 17β-estradiol, but with similar potency as neuroprotector. However, we have previously reported that pretreatment with high concentration (10 μM) of both estrogens abolishes their neuroprotection in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf961594903ff52a39e8e1d9b996162
https://pubmed.ncbi.nlm.nih.gov/28634070
https://pubmed.ncbi.nlm.nih.gov/28634070
Autor:
Erik Ropstad, Steven Verhaegen, Irene Beate Sørvik, Marte Bruu Tanum, Ingvar Brandt, Cesilie Granum Castellanos
Publikováno v:
Toxicology and Applied Pharmacology. 332:159-160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb43da3b35a6b0d96a54910a0fad657
https://doi.org/10.1016/j.taap.2017.05.011
https://doi.org/10.1016/j.taap.2017.05.011
Autor:
Ragnhild E. Paulsen, Anders Vik, Irene Beate Sørvik, Jing-Jy Cheng, Trond Vidar Hansen, Eirik Johansson Solum
Publikováno v:
European journal of medicinal chemistry. 85
The synthesis, cytotoxicity, inhibition of tubulin polymerization and anti-angiogenic effects of 15 analogs of 2-methoxyestradiol (1) are reported. The biological studies revealed that the position of nitrogen atom in the heterocyclic ring is importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ac3331b0d41572fd76208d41c57202
https://pubmed.ncbi.nlm.nih.gov/25108078
https://pubmed.ncbi.nlm.nih.gov/25108078
Autor:
Ragnhild E. Paulsen, Irene Beate Sørvik, Gro Haarklou Mathisen, G. R. Øverby, Karen A. Boldingh Debernard, Kirsten Eline Rakkestad
Publikováno v:
Free radical research. 48(10)
During the last decades it has been shown that estrogen may have neuroprotective functions in the CNS. However, we have previously reported that pretreatment with estradiol abolishes its protection of cultured cerebellar granule neurons from glutamat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be59dfd7a73c2047c13ef0ebf0507861
https://pubmed.ncbi.nlm.nih.gov/24896367
https://pubmed.ncbi.nlm.nih.gov/24896367
Autor:
Ingvar Brandt, Marte Bruu Tanum, Erik Ropstad, Steven Verhaegen, Cesilie Granum Castellanos, Irene Beate Sørvik
Publikováno v:
Toxicology and applied pharmacology. 267(3)
3-Methylsulfonyl-DDE (MeSO₂-DDE) is a potent adrenal toxicant formed from the persistent insecticide DDT. MeSO₂-DDE is widely present in human plasma, milk and fat, and in tissues of marine mammals. In the present study, we investigated endocrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2bb1eb2069ce20eff3ed46a5356e79
https://pubmed.ncbi.nlm.nih.gov/28522354
https://pubmed.ncbi.nlm.nih.gov/28522354