Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Irene Barguilla"'
Autor:
Irene Barguilla, Vicente Candela-Noguera, Patrick Oliver, Balasubramanyam Annangi, Paula Díez, Elena Aznar, Ramón Martínez-Máñez, Ricard Marcos, Alba Hernández, María Dolores Marcos
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16158 (2023)
Mesoporous silica nanoparticles (MSNs) are amongst the most used nanoparticles in biomedicine. However, the potentially toxic effects of MSNs have not yet been fully evaluated, being a controversial matter in research. In this study, bare MSNs, PEGyl
Externí odkaz:
https://doaj.org/article/e032d0ec74784449b12e3938281283d0
Autor:
Irene Barguilla, Veronique Maguer-Satta, Boris Guyot, Susana Pastor, Ricard Marcos, Alba Hernández
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7851 (2023)
One important environmental/health challenge is to determine, in a feasible way, the potential carcinogenic risk associated with environmental agents/exposures. Since a significant proportion of tumors have an environmental origin, detecting the pote
Externí odkaz:
https://doaj.org/article/60c7e48a7133474293814e78f11abf0d
Autor:
Irene Barguilla, Ugutz Unzueta, Jose Vicente Carratalá, Olivia Cano-Garrido, Antonio Villaverde, Alba Hernández, Neus Ferrer-Miralles
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Bacterial inclusion bodies (IBs) are discrete macromolecular complexes that appear in recombinant prokaryotic cells under stress conditions. These structures are often discarded for biotechnological uses given the difficulty in recovering proteins of
Externí odkaz:
https://doaj.org/article/b649b3429f6a4a58818da3fab7718a39
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 2958 (2022)
The increasing accumulation of plastic waste and the widespread presence of its derivatives, micro- and nanoplastics (MNPLs), call for an urgent evaluation of their potential health risks. In the environment, MNPLs coexist with other known hazardous
Externí odkaz:
https://doaj.org/article/66239ef65c2440948ab65ffe39309850
Publikováno v:
Metallomics. 12:2161-2173
Arsenic induces oncogenic effects activating stress-related signalling pathways. This can result in the over-activation of the AP-1 protein, specifically its FRA1 component. FRA1 is a transcription factor frequently overexpressed in epithelial tumors
Autor:
Balasubramanyam Annangi, Antonia Velázquez, Ricard Marcos, Alba Hernández, Gabriela Barszczewska, Josefa Domenech, Irene Barguilla
Publikováno v:
Archives of Toxicology. 94:1973-1984
The nanoparticles (NPs) exposure-related oxidative stress is considered among the main causes of the toxic effects induced by these materials. However, the importance of this mechanism has been mostly explored at short term. Previous experience with
Autor:
Josefa Domenech, Alba Hernández, Sandra Ballesteros, Irene Barguilla, Constanza Cortés, Ricard Marcos
Publikováno v:
Environmental Science: Nano. 7:3431-3446
Accumulation of plastic and its derivatives, micro- and nanoplastics (MNPLs), is a substantial environmental and ecological problem that could potentially become a serious health concern to humans. In this study, we propose an attractive approach to
Publikováno v:
Nanomedicine (London, England). 16(4)
Aim: To detect cell transformation effects of nanoceria after long-term exposure (up to 6 weeks) and to determine their potential interactions with cigarette smoke condensate, as a model of environmental carcinogenic pollutant. Materials & methods: H
Publikováno v:
Metallomics : integrated biometal science. 12(12)
Arsenic induces oncogenic effects activating stress-related signalling pathways. This can result in the over-activation of the AP-1 protein, specifically its FRA1 component. FRA1 is a transcription factor frequently overexpressed in epithelial tumors
Publikováno v:
Toxicology and Applied Pharmacology. 409:115303
DNA damage plays a crucial role in the transforming potential of the human carcinogen arsenic. The arsenic biotransformation enzyme AS3MT is known to participate in the generation of ROS after arsenic exposure, whereas MTH1 sanitizes oxidized dNTP po