Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Irene B. Maroto"'
Autor:
Irene B. Maroto, Carlos Costas-Insua, Coralie Berthoux, Estefanía Moreno, Andrea Ruiz-Calvo, Carlos Montero-Fernández, Andrea Macías-Camero, Ricardo Martín, Nuria García-Font, José Sánchez-Prieto, Giovanni Marsicano, Luigi Bellocchio, Enric I. Canela, Vicent Casadó, Ismael Galve-Roperh, Ángel Núñez, David Fernández de Sevilla, Ignacio Rodríguez-Crespo, Pablo E. Castillo, Manuel Guzmán
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The type-1 cannabinoid receptor (CB1R) is widely expressed in excitatory and inhibitory nerve terminals, and by suppressing neurotransmitter release, its activation modulates neural circuits and brain function. While the interaction of CB1R
Externí odkaz:
https://doaj.org/article/de2f897065d34da0933b217db4f53983
Autor:
Alba Hermoso-López, Carlos Costas-Insua, Carlos Montero-Fernández, Estefanía Moreno, Alicia Álvaro-Blázquez, David Martín-Gutiérrez, Irene B. Maroto-Martínez, Rebeca Diez-Alarcia, Leyre Urigüen, Vicent Casadó, Ignacio Rodríguez-Crespo, Manuel Guzmán
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S848- (2023)
Externí odkaz:
https://doaj.org/article/b668f7103ab240249d28d67435c8975d
Autor:
Laura E Maglio, José A Noriega-Prieto, Irene B Maroto, Jesús Martin-Cortecero, Antonio Muñoz-Callejas, Marta Callejo-Móstoles, David Fernández de Sevilla
Publikováno v:
eLife, Vol 10 (2021)
Insulin-like growth factor-1 (IGF-1) plays a key role in synaptic plasticity, spatial learning, and anxiety-like behavioral processes. While IGF-1 regulates neuronal firing and synaptic transmission in many areas of the central nervous system, its si
Externí odkaz:
https://doaj.org/article/4f62044224414736b4d2eefc48745254
Autor:
David Martín-Gutiérrez, Ignacio Rodríguez-Crespo, Giovanni Marsicano, Joaquin Botta, Leyre Urigüen, José Sánchez-Prieto, Marc Espina, Rebeca Diez-Alarcia, Irene B. Maroto, Carlos Costas-Insua, Nuria García-Font, Raquel Bajo-Grañeras, Peter J. McCormick, Roser Cortés, Vicent Casadó, Andrea Ruiz-Calvo, Manuel Guzmán, Enric I. Canela, M. Teresa Vilaró, Ismael Galve-Roperh, Estefanía Moreno, Silvia Ginés, Guadalupe Mengod, Luigi Bellocchio, Ricardo Martín
Publikováno v:
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2021, 41 (38), pp.7924-7941. ⟨10.1523/JNEUROSCI.0821-21.2021⟩
Addi. Archivo Digital para la Docencia y la Investigación
instname
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona
Journal of Neuroscience, Society for Neuroscience, 2021, 41 (38), pp.7924-7941. ⟨10.1523/JNEUROSCI.0821-21.2021⟩
Addi. Archivo Digital para la Docencia y la Investigación
instname
Digital.CSIC. Repositorio Institucional del CSIC
Dipòsit Digital de la UB
Universidad de Barcelona
Cannabinoids, the bioactive constituents of cannabis, exert a wide array of effects on the brain by engaging Type 1 cannabinoid receptor (CB1R). Accruing evidence supports that cannabinoid action relies on context-dependent factors, such as the biolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37fb9bb32a834bae66d420b7820be79
http://hdl.handle.net/2445/181159
http://hdl.handle.net/2445/181159
Autor:
Carlos, Costas-Insua, Estefanía, Moreno, Irene B, Maroto, Andrea, Ruiz-Calvo, Raquel, Bajo-Grañeras, David, Martín-Gutiérrez, Rebeca, Diez-Alarcia, M Teresa, Vilaró, Roser, Cortés, Nuria, García-Font, Ricardo, Martín, Marc, Espina, Joaquín, Botta, Silvia, Ginés, Peter J, McCormick, José, Sánchez-Prieto, Ismael, Galve-Roperh, Guadalupe, Mengod, Leyre, Urigüen, Giovanni, Marsicano, Luigi, Bellocchio, Enric I, Canela, Vicent, Casadó, Ignacio, Rodríguez-Crespo, Manuel, Guzmán
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 41(38)
Cannabinoids, the bioactive constituents of cannabis, exert a wide array of effects on the brain by engaging Type 1 cannabinoid receptor (CB
Autor:
Irene B. Maroto, Antonio Muñoz-Callejas, David Fernández de Sevilla, Laura Eva Maglio, Jesus Martin-Cortecero, Marta Callejo-Móstoles, José A Noriega-Prieto
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
SUMMARYInsulin-like growth factor-1 (IGF-1) plays a key role in synaptic plasticity, degenerative diseases, spatial learning, and anxiety-like behavioral processes. While IGF-1 regulates neuronal activity in many areas of the brain, its effect on syn
Autor:
Raquel Bajo-Grañeras, Silvia Ortega-Gutiérrez, Rudolf Zechner, Irene B. Maroto, Andrea Ruiz-Calvo, Debora Zian, Eva Resel, Luigi Bellocchio, Manuel Guzmán, Robert Zimmermann, Elena García-Taboada, Gernot F. Grabner, Ismael Galve-Roperh
Publikováno v:
Neuropharmacology. 150:134-144
Cannabinoids exert neuroprotection in a wide array of preclinical models. A number of these studies has focused on cannabinoid CB1 receptors in striatal medium spiny neurons (MSNs) and the most characteristic MSN-degenerative disease, Huntington's di
Autor:
Laura Eva Maglio, David Fernández de Sevilla, Irene B. Maroto, José A Noriega-Prieto, Marta Callejo-Móstoles, Jesus Martin-Cortecero, Antonio Muñoz-Callejas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7667d44f4203f66085799861d4838727
https://doi.org/10.7554/elife.67267.sa2
https://doi.org/10.7554/elife.67267.sa2
Autor:
Anna Chiarlone, Giovanni Marsicano, Jose A. Rodriguez-Navarro, Andrea Ruiz-Calvo, Irene B. Maroto, José Sánchez-Prieto, Manuel Guzmán, Luigi Bellocchio, José Javier Ferrero, Eva Resel, Ismael Galve-Roperh, Angel Gaudioso, Raquel Bajo-Grañeras
Publikováno v:
Cerebral Cortex. 28:307-322
The vast majority of neurons within the striatum are GABAergic medium spiny neurons (MSNs), which receive glutamatergic input from the cortex and thalamus, and form two major efferent pathways: the direct pathway, expressing dopamine D1 receptor (D1R
The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls
Autor:
Carlos Costas-Insua, Alba Hermoso-López, Estefanía Moreno, Carlos Montero-Fernández, Alicia Álvaro-Blázquez, Irene B Maroto, Andrea Sánchez-Ruiz, Rebeca Diez-Alarcia, Cristina Blázquez, Paula Morales, Enric I Canela, Vicent Casadó, Leyre Urigüen, Gertrudis Perea, Luigi Bellocchio, Ignacio Rodríguez-Crespo, Manuel Guzmán
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 755-783 (2024)
Abstract Cereblon/CRBN is a substrate-recognition component of the Cullin4A-DDB1-Roc1 E3 ubiquitin ligase complex. Destabilizing mutations in the human CRBN gene cause a form of autosomal recessive non-syndromic intellectual disability (ARNSID) that
Externí odkaz:
https://doaj.org/article/5c7b69f9446144719e20ce1f4a631547