Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Irene A, Malaty"'
Autor:
Angelo Antonini, K. Ray Chaudhuri, Josefa Domingos, Joohi Jimenez-Shahed, Jack Wright, Connie H. Yan, Ali Alobaidi, Lars Bergmann, Koray Onuk, Linda Harmer, Irene A. Malaty
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-4 (2024)
Abstract The 5-2-1 criteria was developed to facilitate the identification and referral of patients with Parkinson’s Disease (PD) inadequately controlled by oral medications. The criterion was not developed to screen patients with PD for device-aid
Externí odkaz:
https://doaj.org/article/883ecde81a8b417fa8d4333cdc41ef4f
Publikováno v:
Dystonia, Vol 2 (2023)
Background: Spinocerebellar ataxia 17 (SCA17) is a rare autosomal dominant trinucleotide disorder. There are no effective therapies for addressing the clinical symptoms of SCA17.Case report: We describe a 46-year-old male who presented with symptoms
Externí odkaz:
https://doaj.org/article/ad1a07ece0b54f668510ebc7cbed8c15
Autor:
Irene A. Malaty, Pablo Martinez-Martin, K. Ray Chaudhuri, Per Odin, Matej Skorvanek, Joohi Jimenez-Shahed, Michael J. Soileau, Susanna Lindvall, Josefa Domingos, Sarah Jones, Ali Alobaidi, Yash J. Jalundhwala, Prasanna L. Kandukuri, Koray Onuk, Lars Bergmann, Samira Femia, Michelle Y. Lee, Jack Wright, Angelo Antonini
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background The burden of Parkinson’s disease (PD) worsens with disease progression. However, the lack of objective and uniform disease classification challenges our understanding of the incremental burden in patients with advanced Parkinso
Externí odkaz:
https://doaj.org/article/870078f6bdd4457eb525d8f5900a9200
Autor:
Fotis Tsetsos, Dongmei Yu, Jae Hoon Sul, Alden Y. Huang, Cornelia Illmann, Lisa Osiecki, Sabrina M. Darrow, Matthew E. Hirschtritt, Erica Greenberg, Kirsten R. Muller-Vahl, Manfred Stuhrmann, Yves Dion, Guy A. Rouleau, Harald Aschauer, Mara Stamenkovic, Monika Schlögelhofer, Paul Sandor, Cathy L. Barr, Marco A. Grados, Harvey S. Singer, Markus M. Nöthen, Johannes Hebebrand, Anke Hinney, Robert A. King, Thomas V. Fernandez, Csaba Barta, Zsanett Tarnok, Peter Nagy, Christel Depienne, Yulia Worbe, Andreas Hartmann, Cathy L. Budman, Renata Rizzo, Gholson J. Lyon, William M. McMahon, James R. Batterson, Danielle C. Cath, Irene A. Malaty, Michael S. Okun, Cheston Berlin, Douglas W. Woods, Paul C. Lee, Joseph Jankovic, Mary M. Robertson, Donald L. Gilbert, Lawrence W. Brown, Barbara J. Coffey, Andrea Dietrich, Pieter J. Hoekstra, Samuel Kuperman, Samuel H. Zinner, Michael Wagner, James A. Knowles, A. Jeremy Willsey, Jay A. Tischfield, Gary A. Heiman, Nancy J. Cox, Nelson B. Freimer, Benjamin M. Neale, Lea K. Davis, Giovanni Coppola, Carol A. Mathews, Jeremiah M. Scharf, Peristera Paschou, on behalf of the Tourette Association of America International Consortium for Genetics, Sabrina Darrow, Roger Kurlan, James F. Leckman, Jan H. Smit, the Gilles de la Tourette GWAS Replication Initiative, Harald Aschauer Harald Aschauer, Anastasios Konstantinidis, Kirsten Müller-Vahl, Tomasz Wolanczyk, the Tourette International Collaborative Genetics Study, Lawrence Brown, Keun-Ah Cheon, Blanca Garcia-Delgar, Donald Gilbert, Dorothy E. Grice, Julie Hagstrøm, Tammy Hedderly, Isobel Heyman, Chaim Huyser, Young Key Kim, Young-Shin Kim, Yun-Joo Koh, Sodahm Kook, Bennett L. Leventhal, Marcos Madruga-Garrido, Pablo Mir, Astrid Morer, Alexander Münchau, Kerstin J. Plessen, Veit Roessner, Eun-Young Shin, Dong-Ho Song, Jungeun Song, Samuel Zinner, and the Psychiatric Genomics Consortium Tourette Syndrome Working Group, Thomas Fernandez, Gary Heiman, Pieter Hoekstra, Jay Tischfield, Douglas Woods
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Tourette syndrome (TS) is a neuropsychiatric disorder of complex genetic architecture involving multiple interacting genes. Here, we sought to elucidate the pathways that underlie the neurobiology of the disorder through genome-wide analysis
Externí odkaz:
https://doaj.org/article/1e03ee514141459ab171b2316307b113
Autor:
Shannon Y. Chiu, Bhavana Patel, Matthew R. Burns, Joseph Legacy, Aparna Wagle Shukla, Adolfo Ramirez-Zamora, Wissam Deeb, Irene A. Malaty
Publikováno v:
Tremor and Other Hyperkinetic Movements, Vol 10, Iss 0, Pp 1-4 (2020)
Background: Botulinum neurotoxin therapy (BoNT) is a powerful tool for treating many neurologic disorders. The U.S. Food and Drug Administration (FDA)-approved maximum onabotulinum toxin A (OnaA) dose is 400 units (U) per visit, but higher doses are
Externí odkaz:
https://doaj.org/article/be5850bea07a41dfb44def4cbd102b05
Autor:
Ahmad Elkouzi, Adolfo Ramirez‐Zamora, Pam Zeilman, Matthew Barabas, Robert S. Eisinger, Irene A. Malaty, Michael S. Okun, Leonardo Almeida
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 10, Pp 1989-1995 (2019)
Abstract Objective To evaluate the effectiveness of levodopa‐carbidopa intestinal gel (LCIG) as an add‐on rescue therapy following deep brain stimulation (DBS) for treatment of motor fluctuations. Background Both DBS and LCIG are FDA‐approved t
Externí odkaz:
https://doaj.org/article/132f04b4632c4bcfb4c997297f9e2fc8
Autor:
Joshua K. Wong, Melissa J. Armstrong, Leonardo Almeida, Aparna Wagle Shukla, Addie Patterson, Michael S. Okun, Irene A. Malaty
Publikováno v:
Frontiers in Human Neuroscience, Vol 14 (2020)
Introduction:Typing on a keyboard requires complex collaboration between visuospatial/procedural memory, language, and motor function. The impaired ability to type, independent of motor deficits, apraxia, or aphasia has been coined “dystypia.”Cas
Externí odkaz:
https://doaj.org/article/535b58fb67c64ca5bcc6288edd33d3ae
Autor:
Fotis Tsetsos, Apostolia Topaloudi, Pritesh Jain, Zhiyu Yang, Dongmei Yu, Petros Kolovos, Zeynep Tumer, Renata Rizzo, Andreas Hartmann, Christel Depienne, Yulia Worbe, Kirsten R. Müller-Vahl, Danielle C. Cath, Dorret I. Boomsma, Tomasz Wolanczyk, Cezary Zekanowski, Csaba Barta, Zsofia Nemoda, Zsanett Tarnok, Shanmukha S. Padmanabhuni, Joseph D. Buxbaum, Dorothy Grice, Jeffrey Glennon, Hreinn Stefansson, Bastian Hengerer, Evangelia Yannaki, John A. Stamatoyannopoulos, Noa Benaroya-Milshtein, Francesco Cardona, Tammy Hedderly, Isobel Heyman, Chaim Huyser, Pablo Mir, Astrid Morer, Norbert Mueller, Alexander Munchau, Kerstin J. Plessen, Cesare Porcelli, Veit Roessner, Susanne Walitza, Anette Schrag, Davide Martino, Jay A. Tischfield, Gary A. Heiman, A. Jeremy Willsey, Andrea Dietrich, Lea K. Davis, James J. Crowley, Carol A. Mathews, Jeremiah M. Scharf, Marianthi Georgitsi, Pieter J. Hoekstra, Peristera Paschou, Cathy L. Barr, James R. Batterson, Cheston Berlin, Cathy L. Budman, Giovanni Coppola, Nancy J. Cox, Sabrina Darrow, Yves Dion, Nelson B. Freimer, Marco A. Grados, Erica Greenberg, Matthew E. Hirschtritt, Alden Y. Huang, Cornelia Illmann, Robert A. King, Roger Kurlan, James F. Leckman, Gholson J. Lyon, Irene A. Malaty, William M. McMahon, Benjamin M. Neale, Michael S. Okun, Lisa Osiecki, Mary M. Robertson, Guy A. Rouleau, Paul Sandor, Harvey S. Singer, Jan H. Smit, Jae Hoon Sul, Christos Androutsos, Entela Basha, Luca Farkas, Jakub Fichna, Piotr Janik, Mira Kapisyzi, Iordanis Karagiannidis, Anastasia Koumoula, Peter Nagy, Joanna Puchala, Natalia Szejko, Urszula Szymanska, Vaia Tsironi, Alan Apter, Juliane Ball, Benjamin Bodmer, Emese Bognar, Judith Buse, Marta Correa Vela, Carolin Fremer, Blanca Garcia-Delgar, Mariangela Gulisano, Annelieke Hagen, Julie Hagstrøm, Marcos Madruga-Garrido, Alessandra Pellico, Daphna Ruhrman, Jaana Schnell, Paola Rosaria Silvestri, Liselotte Skov, Tamar Steinberg, Friederike Tagwerker Gloor, Victoria L. Turner, Elif Weidinger, John Alexander, Tamas Aranyi, Wim R. Buisman, Jan K. Buitelaar, Nicole Driessen, Petros Drineas, Siyan Fan, Natalie J. Forde, Sarah Gerasch, Odile A. van den Heuvel, Cathrine Jespersgaard, Ahmad S. Kanaan, Harald E. Möller, Muhammad S. Nawaz, Ester Nespoli, Luca Pagliaroli, Geert Poelmans, Petra J.W. Pouwels, Francesca Rizzo, Dick J. Veltman, Ysbrand D. van der Werf, Joanna Widomska, Nuno R. Zilhäo, Lawrence W. Brown, Keun-Ah Cheon, Barbara J. Coffey, Thomas V. Fernandez, Donald L. Gilbert, Hyun Ju Hong, Laura Ibanez-Gomez, Eun-Joo Kim, Young Key Kim, Young-Shin Kim, Yun-Joo Koh, Sodahm Kook, Samuel Kuperman, Bennett L. Leventhal, Athanasios Maras, Tara L. Murphy, Eun-Young Shin, Dong-Ho Song, Jungeun Song, Matthew W. State, Frank Visscher, Sheng Wang, Samuel H. Zinner
Publikováno v:
Biological Psychiatry. Elsevier USA
Biological psychiatry. Elsevier USA
The TSAICG, The TIC Genetics Collaborative Group, The TSGeneSEE Initiative, The EMTICS Collaborative Group, The TS-EUROTRAIN Network & The PGC TS Working Group 2023, ' Genome-wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2023.01.023
Tsetsos, F, Topaloudi, A, Jain, P, Cath, D C, Boomsma, D I, Georgitsi, M, Hoekstra, P J, Paschou, P & Tourette Syndrome Association International Consortium for Genetics (TSAICG) 2023, ' Genome-wide Association Study points to novel locus for Gilles de la Tourette Syndrome ', Biological psychiatry . https://doi.org/10.1016/j.biopsych.2023.01.023
Biological psychiatry. Elsevier USA
The TSAICG, The TIC Genetics Collaborative Group, The TSGeneSEE Initiative, The EMTICS Collaborative Group, The TS-EUROTRAIN Network & The PGC TS Working Group 2023, ' Genome-wide Association Study Points to Novel Locus for Gilles de la Tourette Syndrome ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2023.01.023
Tsetsos, F, Topaloudi, A, Jain, P, Cath, D C, Boomsma, D I, Georgitsi, M, Hoekstra, P J, Paschou, P & Tourette Syndrome Association International Consortium for Genetics (TSAICG) 2023, ' Genome-wide Association Study points to novel locus for Gilles de la Tourette Syndrome ', Biological psychiatry . https://doi.org/10.1016/j.biopsych.2023.01.023
Background: Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder of complex genetic architecture and is characterized by multiple motor tics and at least one vocal tic persisting for more than 1 year. Methods: We performed a genome
Autor:
Jessica Frey, Irene A. Malaty
Publikováno v:
Current Neurology and Neuroscience Reports
Purpose of Review This study aims to examine the treatments currently available for Tourette syndrome (TS) and to discuss evolving therapies, spanning behavioral, pharmacologic, complementary and alternative medicine, and neuromodulation approaches.
Autor:
Irene A. Malaty, Kirsten R. Müller-Vahl, David Shprecher, Davide Martino, Tamara Pringsheim, Elaheh Nosratmirshekarlou, Christos Ganos
Publikováno v:
European Child & Adolescent Psychiatry. 32:859-872
A standardized definition of treatment failure in the management of tics is currently lacking. Such definition would prevent persistent use of unnecessary interventions and help clinicians to determine when to offer less established treatments (e.g.,