Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Irene, Sangrador"'
Autor:
Laura Solé, Teresa Lobo-Jarne, Daniel Álvarez-Villanueva, Josune Alonso-Marañón, Yolanda Guillén, Marta Guix, Irene Sangrador, Catalina Rozalén, Anna Vert, Antonio Barbachano, Joan Lop, Marta Salido, Beatriz Bellosillo, Raquel García-Romero, Marta Garrido, Jessica González, María Martínez-Iniesta, Erika López-Arribillaga, Ramón Salazar, Clara Montagut, Ferrán Torres, Mar Iglesias, Toni Celià-Terrassa, Alberto Muñoz, Alberto Villanueva, Anna Bigas, Lluís Espinosa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The failure of chemotherapy in colorectal cancer is currently unclear. Here, the authors show that upon sub-lethal dose of chemotherapy wild-type p53 colorectal cancers acquire a quiescence-like phenotype and a YAP-dependent fetal-like intestinal ste
Externí odkaz:
https://doaj.org/article/a95e4335e7804b569fac9baa390c372b
Autor:
Eva C. Vaquero, Antoni Castells, Cristina Fillat, Manuel Domínguez-Fraile, Esther Samper, Maria Rovira-Rigau, Sebastià Franch-Expósito, Fiona Campbell, Xavier Molero, Irene Sangrador
Zeb1 hemizygosity doesn't prevent long term development of PDAC in 30-weeks old KPC;Z+/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d1cd62b3f83d418d53e5311fba7113
https://doi.org/10.1158/0008-5472.22416860.v1
https://doi.org/10.1158/0008-5472.22416860.v1
Autor:
Eva C. Vaquero, Antoni Castells, Cristina Fillat, Manuel Domínguez-Fraile, Esther Samper, Maria Rovira-Rigau, Sebastià Franch-Expósito, Fiona Campbell, Xavier Molero, Irene Sangrador
Antibodies used for immunohistochemistry and immunofluorescence (Table 1), and for western blot (Table 2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4570743f22ce427b8956b50fae38ef8b
https://doi.org/10.1158/0008-5472.22416851
https://doi.org/10.1158/0008-5472.22416851
Autor:
Eva C. Vaquero, Antoni Castells, Cristina Fillat, Manuel Domínguez-Fraile, Esther Samper, Maria Rovira-Rigau, Sebastià Franch-Expósito, Fiona Campbell, Xavier Molero, Irene Sangrador
The transcription factor Zeb1 has been identified as a crucial player in Kras-dependent oncogenesis. In pancreatic ductal adenocarcinoma (PDAC), Zeb1 is highly expressed in myofibroblasts and correlates with poor prognosis. As Kras mutations are key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763d8e33d4433d08571355800775c747
https://doi.org/10.1158/0008-5472.c.6509666
https://doi.org/10.1158/0008-5472.c.6509666
Autor:
Angel M. Carcaboso, Soledad Gomez-Gonzalez, Gwenvael Le Dréau, Elisa Martí, Lucía Fanlo-Escudero, Elena Rebollo, Cinzia Lavarino, Toni Celià-Terrassa, Emmanuel L. Gautier, Irene Sangrador, Monica Vila-Ubach, Susana Usieto
Neuroblastoma is a pediatric cancer that can present as low- or high-risk tumors (LR-NBs and HR-NBs), the latter group showing poor prognosis due to metastasis and strong resistance to current therapy. NBs are known to originate from alterations to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81639e0d6edca8314cf0c94a13298ce9
https://doi.org/10.1101/2021.11.26.470092
https://doi.org/10.1101/2021.11.26.470092
Autor:
Irene Sangrador, Antonio Barbáchano, Joan Lop, Ferran Torres, Laura Solé, Jessica González, Anna Vert, Marta I. Garrido, Alberto Villanueva, Toni Celià-Terrassa, Anna Bigas, Raquel García-Romero, Ramon Salazar, María Martínez-Iniesta, C. Montagut, Mar Iglesias, Marta Guix, Teresa Lobo-Jarne, Yolanda Guillén, Marta Salido, Erika López-Arribillaga, Lluis Espinosa, Beatriz Bellosillo, Alberto Muñoz
Current therapy against colorectal cancer is based on DNA-damaging agents that eradicate highly proliferative malignant cells. Whether sublethal chemotherapy affects tumor cell behavior and impacts on patient outcome is primarily unstudied. We now sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4324cec90d870803b730170c8f4d0eb
https://doi.org/10.1101/2021.04.08.438915
https://doi.org/10.1101/2021.04.08.438915
Autor:
Iván Pérez-Núñez, Catalina Rozalén, José Ángel Palomeque, Irene Sangrador, Mariona Dalmau, Laura Comerma, Anna Hernández-Prat, David Casadevall, Silvia Menendez, Daniel Dan Liu, Minhong Shen, Jordi Berenguer, Irene Rius Ruiz, Raul Peña, José Carlos Montañés, M. Mar Albà, Sarah Bonnin, Julia Ponomarenko, Roger R. Gomis, Juan Miguel Cejalvo, Sonia Servitja, Diego M. Marzese, Lluis Morey, Leonie Voorwerk, Joaquín Arribas, Begoña Bermejo, Marleen Kok, Lajos Pusztai, Yibin Kang, Joan Albanell, Toni Celià-Terrassa
Publikováno v:
Nature cancer. 3(3)
Ligand-dependent corepressor (LCOR) mediates normal and malignant breast stem cell differentiation. Cancer stem cells (CSCs) generate phenotypic heterogeneity and drive therapy resistance, yet their role in immunotherapy is poorly understood. Here we
Autor:
Xavier Molero, Sebastià Franch-Expósito, Maria Rovira-Rigau, Esther Samper, Fiona Campbell, Antoni Castells, Eva C. Vaquero, Manuel Domínguez-Fraile, Cristina Fillat, Irene Sangrador
Publikováno v:
Cancer Research. 78:2624-2637
The transcription factor Zeb1 has been identified as a crucial player in Kras-dependent oncogenesis. In pancreatic ductal adenocarcinoma (PDAC), Zeb1 is highly expressed in myofibroblasts and correlates with poor prognosis. As Kras mutations are key
Autor:
Irene, Sangrador, Xavier, Molero, Fiona, Campbell, Sebastià, Franch-Expósito, Maria, Rovira-Rigau, Esther, Samper, Manuel, Domínguez-Fraile, Cristina, Fillat, Antoni, Castells, Eva C, Vaquero
Publikováno v:
Cancer research. 78(10)
The transcription factor Zeb1 has been identified as a crucial player in Kras-dependent oncogenesis. In pancreatic ductal adenocarcinoma (PDAC), Zeb1 is highly expressed in myofibroblasts and correlates with poor prognosis. As Kras mutations are key
Autor:
Cristina Fillat, Xavier Molero, Antoni Castells, Eva C. Vaquero, Fiona Campbell, Irene Sangrador, E. Samper
Publikováno v:
Pancreatology. 17:S19