T Cell Peptide Prediction, Immune Response, and Host–Pathogen Relationship in Vaccinated and Recovered from Mild COVID-19 Subjects

Autor: Iole Macchia, Valentina La Sorsa, Alessandra Ciervo, Irene Ruspantini, Donatella Negri, Martina Borghi, Maria Laura De Angelis, Francesca Luciani, Antonio Martina, Silvia Taglieri, Valentina Durastanti, Maria Concetta Altavista, Francesca Urbani, Fabiola Mancini

Publikováno v: Biomolecules, Vol 14, Iss 10, p 1217 (2024)

COVID-19 remains a significant threat, particularly to vulnerable populations. The emergence of new variants necessitates the development of treatments and vaccines that induce both humoral and cellular immunity. This study aimed to identify potentia

Externí odkaz: https://doaj.org/article/d70778cc12cb480894b4c98047553a86

Multicentre Harmonisation of a Six-Colour Flow Cytometry Panel for Naïve/Memory T Cell Immunomonitoring

Autor: Iole Macchia, Valentina La Sorsa, Irene Ruspantini, Massimo Sanchez, Valentina Tirelli, Maria Carollo, Giorgio Fedele, Pasqualina Leone, Giovanna Schiavoni, Carla Buccione, Paola Rizza, Paola Nisticò, Belinda Palermo, Stefania Morrone, Helena Stabile, Aurelia Rughetti, Marianna Nuti, Ilaria Grazia Zizzari, Cinzia Fionda, Roberta Maggio, Cristina Capuano, Concetta Quintarelli, Matilde Sinibaldi, Chiara Agrati, Rita Casetti, Andrea Rozo Gonzalez, Floriana Iacobone, Angela Gismondi, Filippo Belardelli, Mauro Biffoni, Francesca Urbani

Publikováno v: Journal of Immunology Research, Vol 2020 (2020)

Background. Personalised medicine in oncology needs standardised immunological assays. Flow cytometry (FCM) methods represent an essential tool for immunomonitoring, and their harmonisation is crucial to obtain comparable data in multicentre clinical

Externí odkaz: https://doaj.org/article/04486219890645d4a2e10952819dce83

Type E Botulinum Neurotoxin-Producing Clostridium butyricum Strains Are Aerotolerant during Vegetative Growth

Autor: Serena Camerini, Lucia Marcocci, Lara Picarazzi, Egidio Iorio, Irene Ruspantini, Paola Pietrangeli, Marco Crescenzi, Giovanna Franciosa

Publikováno v: mSystems, Vol 4, Iss 2 (2019)

ABSTRACT Clostridium butyricum, the type species of the genus Clostridium, is considered an obligate anaerobe, yet it has been shown to grow in the presence of oxygen. C. butyricum strains atypically producing the botulinum neurotoxin type E are the

Externí odkaz: https://doaj.org/article/24817de69d9148f7a0fb406bfef2ffb4

The Fatty Acid and Protein Profiles of Circulating CD81-Positive Small Extracellular Vesicles Are Associated with Disease Stage in Melanoma Patients

Autor: Serena Camerini, Santo Raffaele Mercuri, Irene Ruspantini, Carla Raggi, Serena Cecchetti, Antonella Di Biase, Luca Lalli, Cristina Federici, Giovanni Paolino, Elisa Moliterni, Luana Lugini, Elisabetta Vergani, Stefano Calvieri, Veronica Huber, Marialuisa Casella, Flavia Chiarotti, Alberto Macone, Lucia Bertuccini, Francesca Iosi

Publikováno v: Cancers, Vol 13, Iss 4157, p 4157 (2021)
Cancers
Volume 13
Issue 16

Simple Summary Early detection of cutaneous melanoma is the key to increasing survival and proper therapeutic adjustment, especially in stages II–IV. We investigated whether the fatty acid (FA) and protein compositions of small extracellular vesicl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd56565cfc10c715cecbe8fda48a82a
https://www.mdpi.com/2072-6694/13/16/4157

DNA repair protein DNA-PK protects PC12 cells from oxidative stress-induced apoptosis involving AKT phosphorylation

Autor: Irene Ruspantini, Alessio Cardinale, Francesca Silvagno, Leonardo Lupacchini, Serena Saladini, Daniela Merlo, Marco Papale, Enrico Garaci, Cristiana Mollinari, Chiara De Dominicis

Publikováno v: Molecular biology reports (Dordr., Online) (2021). doi:10.1007/s11033-021-06934-5
info:cnr-pdr/source/autori:Alessio Cardinale, Serena Saladini, Leonardo Lupacchini, Irene Ruspantini, Chiara De Dominicis, Marco Papale, Francesca Silvagno, Enrico Garaci, Cristiana Mollinari and Daniela Merlo/titolo:DNA repair protein DNA-PK protects PC12 cells from oxidative stress-induced apoptosis involving AKT phosphorylation/doi:10.1007%2Fs11033-021-06934-5/rivista:Molecular biology reports (Dordr., Online)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume

Background Emerging evidence suggest that DNA-PK complex plays a role in the cellular response to oxidative stress, in addition to its function of double strand break (DSB) repair. In this study we evaluated whether DNA-PK participates in oxidative s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fcff4cf7a48dc72b05f2aed7f1a0c24
http://hdl.handle.net/2318/1835298