Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Irene, Frischauf"'
Autor:
Lena Maltan, Sarah Weiß, Hadil Najjar, Melanie Leopold, Sonja Lindinger, Carmen Höglinger, Lorenz Höbarth, Matthias Sallinger, Herwig Grabmayr, Sascha Berlansky, Denis Krivic, Valentina Hopl, Anna Blaimschein, Marc Fahrner, Irene Frischauf, Adéla Tiffner, Isabella Derler
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The Ca2+ ion channel Orai1 is crucial in immune cells. Here, the authors applied genetic code expansion to transfer light-sensitivity to the Orai1 channel and achieved precise control over its function.
Externí odkaz:
https://doaj.org/article/bee2dd102ac04d1e8838711cbc3c5162
Autor:
Christina Humer, Sascha Berlansky, Herwig Grabmayr, Matthias Sallinger, Andreas Bernhard, Marc Fahrner, Irene Frischauf
Publikováno v:
Cells, Vol 11, Iss 11, p 1849 (2022)
All human life starts with a calcium (Ca2+) wave. This ion regulates a plethora of cellular functions ranging from fertilisation and birth to development and cell death. A sophisticated system is responsible for maintaining the essential, tight conce
Externí odkaz:
https://doaj.org/article/7b9a58a4060b4721b2b301708a5df281
Autor:
Christine Silvia Gibhardt, Sabrina Cappello, Rajesh Bhardwaj, Romana Schober, Sonja Agnes Kirsch, Zuriñe Bonilla del Rio, Stefan Gahbauer, Anna Bochicchio, Magdalena Sumanska, Christian Ickes, Ioana Stejerean-Todoran, Miso Mitkovski, Dalia Alansary, Xin Zhang, Aram Revazian, Marc Fahrner, Victoria Lunz, Irene Frischauf, Ting Luo, Daria Ezerina, Joris Messens, Vsevolod Vadimovich Belousov, Markus Hoth, Rainer Arnold Böckmann, Matthias Albrecht Hediger, Rainer Schindl, Ivan Bogeski
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108292- (2020)
Summary: Store-operated calcium entry (SOCE) through STIM-gated ORAI channels governs vital cellular functions. In this context, SOCE controls cellular redox signaling and is itself regulated by redox modifications. However, the molecular mechanisms
Externí odkaz:
https://doaj.org/article/9aa210ab347a4829a53ce714c6a1e9f1
Autor:
Sascha Berlansky, Matthias Sallinger, Herwig Grabmayr, Christina Humer, Andreas Bernhard, Marc Fahrner, Irene Frischauf
Publikováno v:
Cells, Vol 11, Iss 2, p 253 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). This respiratory illness was declared a pandemic by the world health organization (WHO) in Mar
Externí odkaz:
https://doaj.org/article/9cb5b9e2caf74f139eef58007c82bbc5
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 471 (2021)
The calcium-release-activated calcium (CRAC) channel, activated by the release of Ca2+ from the endoplasmic reticulum (ER), is critical for Ca2+ homeostasis and active signal transduction in a plethora of cell types. Spurred by the long-sought decryp
Externí odkaz:
https://doaj.org/article/f588cc4d1de04b03b11d92749a22018a
Autor:
Matthias Sallinger, Adéla Tiffner, Tony Schmidt, Daniel Bonhenry, Linda Waldherr, Irene Frischauf, Victoria Lunz, Isabella Derler, Romana Schober, Rainer Schindl
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4410 (2020)
Stromal interaction molecule 1 (STIM1) is a ubiquitously expressed Ca2+ sensor protein that induces permeation of Orai Ca2+ channels upon endoplasmic reticulum Ca2+-store depletion. A drop in luminal Ca2+ causes partial unfolding of the N-terminal ST
Externí odkaz:
https://doaj.org/article/fb9d8fc255c8464eb92a6f2a72999084
Autor:
Christina, Humer, Sascha, Berlansky, Herwig, Grabmayr, Matthias, Sallinger, Andreas, Bernhard, Marc, Fahrner, Irene, Frischauf
Publikováno v:
Cells. 11(11)
All human life starts with a calcium (Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b2ef464e8cacd680db6c2f5ee11a1da
https://pubmed.ncbi.nlm.nih.gov/35681544
https://pubmed.ncbi.nlm.nih.gov/35681544
Publikováno v:
Current Opinion in Physiology. 17:42-49
Maintaining a precise calcium (Ca2+) balance is vital for cellular survival. The most prominent pathway to shuttle Ca2+ into cells is the Ca2+ release activated Ca2+ (CRAC) channel. Orai proteins are indispensable players in this central mechanism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f045567e3bb243f5bfa195e84eaecd92
https://doi.org/10.1016/j.cophys.2020.06.006
https://doi.org/10.1016/j.cophys.2020.06.006
Autor:
Derler, Adéla Tiffner, Valentina Hopl, Romana Schober, Matthias Sallinger, Herwig Grabmayr, Carmen Höglinger, Marc Fahrner, Victoria Lunz, Lena Maltan, Irene Frischauf, Denis Krivic, Rajesh Bhardwaj, Rainer Schindl, Matthias A. Hediger, Isabella
Publikováno v:
Cancers; Volume 13; Issue 24; Pages: 6357
The interplay of SK3, a Ca2+ sensitive K+ ion channel, with Orai1, a Ca2+ ion channel, has been reported to increase cytosolic Ca2+ levels, thereby triggering proliferation of breast and colon cancer cells, although a molecular mechanism has remained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::060c988f53744e55d7420e9b5ed66718
Autor:
Adéla Tiffner, Valentina Hopl, Romana Schober, Matthias Sallinger, Herwig Grabmayr, Carmen Höglinger, Marc Fahrner, Victoria Lunz, Lena Maltan, Irene Frischauf, Denis Krivic, Rajesh Bhardwaj, Rainer Schindl, Matthias A. Hediger, Isabella Derler
Publikováno v:
Cancers
Cancers, Vol 13, Iss 6357, p 6357 (2021)
Cancers, Vol 13, Iss 6357, p 6357 (2021)
Simple Summary Breast, colon, and prostate cancer account for about a third of cancer cases and a fifth of cancer deaths. At the molecular level, one reason for the development of cancer is the dysfunction or altered co-regulation of cellular protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::376a4dfd641fd3ab9af406ff793dd821
https://pubmed.ncbi.nlm.nih.gov/34944977
https://pubmed.ncbi.nlm.nih.gov/34944977