Effectiveness of pharmacological treatments for severe agitation in real-world emergency settings: protocol of individual-participant-data network meta-analysis

Autor: Spyridon Siafis, Hui Wu, Nobuyuki Nomura, Johannes Schneider-Thoma, Irene Bighelli, Carolin Lorenz, Joseph E. Dib, Prathap Tharyan, Leonie A. Calver, Geoffrey K. Isbister, Esther W. Y. Chan, Jonathan C. Knott, Celene Y. L. Yap, Célia Mantovani, Marc L. Martel, David Barbic, William G. Honer, Wulf-Peter Hansen, Gisele Huf, Jacob Alexander, Nirmal S. Raveendran, Evandro S. F. Coutinho, Josef Priller, Clive E. Adams, Georgia Salanti, Stefan Leucht

Publikováno v: Systematic Reviews, Vol 13, Iss 1, Pp 1-11 (2024)

Abstract Background Severe psychomotor agitation and aggression often require immediate pharmacological intervention, but clear evidence-based recommendations for choosing among the multiple options are lacking. To address this gap, we plan a systema

Externí odkaz: https://doaj.org/article/3b0d75a1b9c946069ec67702c27c2c95

Psychological interventions for early-phase schizophrenia: protocol for a systematic review and network meta-analysis [version 2; peer review: 2 approved, 1 approved with reservations]

Autor: Lena Feber, Stefan Leucht, Irene Bighelli, Josef Priller, Wulf-Peter Hansen, Nurul Husna Salahuddin, Mathias Harrer, Georgia Salanti

Publikováno v: F1000Research, Vol 13 (2024)

Introduction Treating the early phase of schizophrenia is crucial for preventing further episodes and improving quality of life, functioning, and social inclusion. Pharmacotherapies are first-line treatments, but have limitations. There is consensus

Externí odkaz: https://doaj.org/article/65b25af18b1542418e3677806bcf2b2e

Changes in the prevalence of mental health problems during the first year of the pandemic: a systematic review and dose-response meta-analysis

Autor: Toshi A Furukawa, Edoardo G Ostinelli, Andrea Cipriani, Pim Cuijpers, Lin Ma, Akira Onishi, Tianjing Li, Georgia Salanti, Vikram Patel, Christian Kieling, Sanae Kishimoto, Ronald C Kessler, Seena Fazel, Marialena Trivella, Akira Sato, Yikang Zhu, Raman Sharma, Matthias Egger, Simone N. Vigod, Yu-Kang Tu, Tou-Yuan Tsai, Yuan-Pang Wang, Irene Bighelli, Alessandro Rodolico, Stefan Leucht, Michael Ostacher, Ian White, Virginia Chiocchia, Ethan Sahker, Rie Toyomoto, Kazufumi Yoshida, Trevor Thompson, Dongfang Wang, Jing Tian, Katharine A Smith, Gonzalo Arrondo, Meenakshi Sharma, Silviya Ralovska, Andreas D Haas, Michael A Wewege, Bartosz Helfer, Erika Kalocsanyiova, Harrison Nelson, Gandy Dolores-Maldonado, Caroline Zangani, Kenji Omae, Shimeng Dong, Shino Kikuchi, Thomy Tonia, James S W Hong, Natalie Luise Peter, Letao Sun, Aurélie M Lasserre, Alexander Holloway, Leila Darwish, Andrea Zucchetti, Amin Sharifan, Ana Cristina Solis, Antonio Vita, Carmen Concerto, Chinonso Igwesi-Chidobe, Carlos Rios-Gonzalez, Anna Ceraso, Daniel Prates Baldez, Dicle Dilay Demir, Ying-Chun Lin, Elena Invernizzi, Gabriel Henrique Beraldi, Gamze Erzin, Giulia Ottaviano, Graciela J Balbin-Ramón, Chin-Yen Ho, Helio Elkis, Yun Chen Liu, Javier Ballesteros, Johanna Schneckenburger, Jessie Jingxia Lin, Abdulkadir Usman Sambo, Lena Feber, Mattia Marchetti, Mauro Italia, Mengchang Qin, Yi-Chih Lin, Nurul Husna Salahuddin, Rossella Virgillito, Ogulcan Ciray, Sergio A Covarrubias-Castillo, Yun Hsia, Shiue-Shiuan Tu, Vidya Giri Shankar

Publikováno v: BMJ Mental Health, Vol 27, Iss 1 (2024)

Aim To describe the pattern of the prevalence of mental health problems during the first year of the COVID-19 pandemic and examine the impact of containment measures on these trends.Methods We identified articles published until 30 August 2021 that r

Externí odkaz: https://doaj.org/article/7c865ac5b5544c68b6da64e797d48ddd

Antipsychotic drugs and their effects on cognitive function: protocol for a systematic review, pairwise, and network meta-analysis

Autor: Lena Feber, Natalie Peter, Johannes Schneider-Thoma, Spyridon Siafis, Irene Bighelli, Wulf-Peter Hansen, Daniel Prates Baldez, Georgia Salanti, Richard S. E. Keefe, Rolf R. Engel, Stefan Leucht

Publikováno v: Systematic Reviews, Vol 12, Iss 1, Pp 1-8 (2023)

Abstract Background There is evidence that antipsychotic drugs differ in their effect on the cognitive symptoms of schizophrenia. So far, there is no comprehensive systematic review available that would enable providers and patients to make informed

Externí odkaz: https://doaj.org/article/35325f794d4747a187fa9459914e9876

Efficacy of clozapine compared with other second-generation antipsychotic drugs in patients with treatment-resistant schizophrenia: protocol for a systematic review and individual patient data meta-analysis of randomised controlled trials

Autor: Georgia Salanti, Irene Bighelli, Wulf-Peter Hansen, Stefan Leucht, Johannes Schneider-Thoma, John M Davis, Tasnim Hamza, Spyridon Siafis, Shimeng Dong

Publikováno v: BMJ Open, Vol 13, Iss 2 (2023)

Introduction Guidelines recommend clozapine for treatment-resistant schizophrenia. However, meta-analysis of aggregate data (AD) did not demonstrate higher efficacy of clozapine compared with other second-generation antipsychotics but found substanti

Externí odkaz: https://doaj.org/article/513d6142ceed4979b55f70480b3dc03d