Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Irena Zentsová"'
Autor:
Zuzana Parackova, Irena Zentsova, Marketa Bloomfield, Adam Klocperk, Rudolf Horvath, Hana Malcova, Dita Cebecauerova, Anna Sediva
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionJuvenile idiopathic arthritis (JIA), a clinically variable disease characterized by autoimmune arthritis, affects children, and its immunopathology remains elusive. Alterations in neutrophil biology play an important role in this disease.
Externí odkaz:
https://doaj.org/article/3c1ff646c020478199aeb355809d1dc2
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Patients with STAT1 gain-of-function (GOF) mutations suffer from an inborn error of immunity hallmarked by chronic mucocutaneous candidiasis (CMC). The pathogenesis behind this complex and heterogeneous disease is still incompletely understood. Beyon
Externí odkaz:
https://doaj.org/article/ff55e25e2d0344048322da674f0ed1b3
Autor:
Zuzana Parackova, Irena Zentsova, Petra Vrabcova, Adam Klocperk, Zdenek Sumnik, Stepanka Pruhova, Lenka Petruzelkova, Robert Hasler, Anna Sediva
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neutrophils releasing neutrophil extracellular traps (NETs) infiltrate the pancreas prior to type 1 diabetes (T1D) onset; however, the precise nature of their contribution to disease remains poorly defined. To examine how NETs affect immune functions
Externí odkaz:
https://doaj.org/article/5333061925c045c182ea366222199c06
Autor:
Irena Zentsova, Zuzana Parackova, Jana Kayserova, Lenka Palova-Jelinkova, Petra Vrabcova, Nikol Volfova, Zdenek Sumnik, Stepanka Pruhova, Lenka Petruzelkova, Anna Sediva
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
Inflammasomes are large protein complexes involved in the maturation of IL-1β, a cytokine associated with the pathophysiology of type 1 diabetes (T1D). The data presented in this article focused on the role of inflammasomes in DNA recognition in T1D
Externí odkaz:
https://doaj.org/article/4b11c74f4b424bceb39ab1d851585156
Autor:
Veronika Kanderova, Hana Grombirikova, Irena Zentsova, Kamila Reblova, Adam Klocperk, Martina Fejtkova, Marketa Bloomfield, Barbora Ravcukova, Tomas Kalina, Tomas Freiberger, Anna Sediva
Publikováno v:
Haematologica, Vol 104, Iss 1 (2019)
Externí odkaz:
https://doaj.org/article/e499ab134e854d8c9b7d672745285506
Autor:
Zuzana Parackova, Irena Zentsova, Marketa Bloomfield, Petra Vrabcova, Jitka Smetanova, Adam Klocperk, Grigorij Mesežnikov, Luis Fernando Casas Mendez, Tomas Vymazal, Anna Sediva
Publikováno v:
Cells, Vol 9, Iss 10, p 2206 (2020)
COVID-19, caused by SARS-CoV-2 virus, emerged as a pandemic disease posing a severe threat to global health. To date, sporadic studies have demonstrated that innate immune mechanisms, specifically neutrophilia, NETosis, and neutrophil-associated cyto
Externí odkaz:
https://doaj.org/article/d55db0ead0674da38051e88db0faa477
Signal transducer and activator of transcription 1 (STAT1) gain-of-function (GOF) mutations underlie an inborn error of immunity called chronic mucocutaneous candidiasis. Beyond the fungal susceptibility, attributed to Th17 failure, over half of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::267c221ae99c4f355dad80d77e2e0568
https://doi.org/10.22541/au.165629547.71126020/v1
https://doi.org/10.22541/au.165629547.71126020/v1
Publikováno v:
Journal of Landscape Ecology, Vol 6, Iss 1, Pp 18-31 (2013)
Three to four dominant seed-transporting ant species of different size categories (Tetramorium caespitum, Lasius niger, Formica rufibarbis/Formica pratensis) on the plateau of abandoned ore sedimentation basin (tailings containment) were studied as p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3822b703b6f487d84df92493dc03e8ab
https://doaj.org/article/7d6ad1b2afd24456998f31282eff071d
https://doaj.org/article/7d6ad1b2afd24456998f31282eff071d
Autor:
Zuzana Parackova, Irena Zentsova, Hana Malcova, Dita Cebecauerova, Anna Sediva, Rudolf Horvath
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
ObjectivePosttranslational modifications (PTMs) of proteins are crucial for regulating various biological processes. However, protein alteration via PTMs, and consequently, the creation of new epitopes, can induce abnormal autoimmune responses in pre
Externí odkaz:
https://doaj.org/article/ac7986ddf6764a2eb0a759c64e14bd71
Autor:
Adam Klocperk, Jana Vcelakova, Petra Vrabcova, Irena Zentsova, Lenka Petruzelkova, Zdenek Sumnik, Stepanka Pruhova, Anna Sediva, Zuzana Parackova
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Type 1 diabetes (T1D) is an autoimmune disorder with unambiguous involvement of both innate and adaptive immune mechanisms in the destruction of pancreatic beta cells. Recent evidence demonstrated that neutrophils infiltrate the pancreas prior to dis
Externí odkaz:
https://doaj.org/article/a169e107ee2647559c422730bc83fbee