Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Irena Vackova"'
Autor:
Olena Rogulska, Irena Vackova, Simon Prazak, Karolina Turnovcova, Sarka Kubinova, Lucie Bacakova, Pavla Jendelova, Yuriy Petrenko
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The widespread use of multipotent mesenchymal stromal cell-derived secretome (MSC-sec) requires optimal preservation methods. Lyophilization offers benefits like concentrating the secretome, reducing the storage volume, and making storage co
Externí odkaz:
https://doaj.org/article/b69cd7bdb7c84d20946c5b430b7abecd
Publikováno v:
Polymers, Vol 14, Iss 13, p 2553 (2022)
The regulatory requirements in cell processing, in the choice of a biomaterial scaffold and in quality control analysis, have to be followed in the clinical application of tissue-engineered grafts. Confirmation of sterility during quality control stu
Externí odkaz:
https://doaj.org/article/a71f9309cade4070bc77041ef3a8c059
Autor:
Yuriy Petrenko, Milada Chudickova, Irena Vackova, Tomas Groh, Eliska Kosnarova, Jitka Cejkova, Karolina Turnovcova, Alexander Petrenko, Eva Sykova, Sarka Kubinova
Publikováno v:
Stem Cells International, Vol 2019 (2019)
The wide use of human multipotent mesenchymal stromal cells (MSCs) in clinical trials requires a full-scale safety and identity evaluation of the cellular product and subsequent transportation between research/medical centres. This necessitates the p
Externí odkaz:
https://doaj.org/article/e74b66be2abb4b19b70e5cec5873ebd9
Autor:
Milada Chudickova, Irena Vackova, Lucia Machova Urdzikova, Pavlina Jancova, Kristyna Kekulova, Monika Rehorova, Karolina Turnovcova, Pavla Jendelova, Sarka Kubinova
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4516 (2019)
The transplantation of Wharton’s jelly derived mesenchymal stromal cells (WJ-MSCs) possesses therapeutic potential for the treatment of a spinal cord injury (SCI). Generally, the main effect of MSCs is mediated by their paracrine potential. Therefo
Externí odkaz:
https://doaj.org/article/ba32c43abb8b4734beb57fc1c158af30
Autor:
Ingrid Vargová, Eva Syková, Serhiy Forostyak, Karolina Turnovcova, Petr Vodicka, Helena Kupcova Skalnikova, Pavla Jendelova, Šárka Kubinová, Monika Řehořová, Irena Vackova
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 6, Pp 535-547 (2019)
An increasing number of studies have demonstrated the beneficial effects of human mesenchymal stem cells (hMSC) in the treatment of amyotrophic lateral sclerosis (ALS). We compared the effect of repeated intrathecal applications of hMSC or their cond
Autor:
Šárka Kubinová, Karolina Turnovcova, Yuriy A. Petrenko, Jitka Cejkova, Irena Vackova, Tomas Groh, Milada Chudíčková, Alexander Y. Petrenko, Eliska Kosnarova, Eva Syková
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Stem Cells International
Stem Cells International
The wide use of human multipotent mesenchymal stromal cells (MSCs) in clinical trials requires a full-scale safety and identity evaluation of the cellular product and subsequent transportation between research/medical centres. This necessitates the p
Autor:
Petr Vodicka, Šárka Kubinová, Kristyna Kekulova, Karolina Turnovcova, Irena Vackova, Milada Chudíčková, Yuriy A. Petrenko, Helena Kupcova Skalnikova, Zuzana Kočí
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Multipotent mesenchymal stromal cells (MSCs) can be considered an accessible therapeutic tool for regenerative medicine. Here, we compared the growth kinetics, immunophenotypic and immunomodulatory properties, gene expression and secretome profile of
Autor:
Kristyna Zaviskova, Julie Bystronova, Martin Pravda, Irena Vackova, Ivana Ščigalková, Dmitry Tukmachev, Aleš Hejčl, Jana Dubisova, Šárka Kubinová, Vladimir Velebny, Lucie Wolfova, Romana Sulakova
Publikováno v:
Journal of Biomedical Materials Research Part A. 106:1129-1140
Hydrogel scaffolds which bridge the lesion, together with stem cell therapy represent a promising approach for spinal cord injury (SCI) repair. In this study, a hydroxyphenyl derivative of hyaluronic acid (HA-PH) was modified with the integrin-bindin
Autor:
Karolina Turnovcova, Pavla Jendelova, Kristyna Kekulova, Pavlina Jancova, Milada Chudíčková, Monika Rehorova, Irena Vackova, Šárka Kubinová, Lucia Machova Urdzikova
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4516 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 18
International Journal of Molecular Sciences
Volume 20
Issue 18
The transplantation of Wharton&rsquo
s jelly derived mesenchymal stromal cells (WJ-MSCs) possesses therapeutic potential for the treatment of a spinal cord injury (SCI). Generally, the main effect of MSCs is mediated by their paracrine potential
s jelly derived mesenchymal stromal cells (WJ-MSCs) possesses therapeutic potential for the treatment of a spinal cord injury (SCI). Generally, the main effect of MSCs is mediated by their paracrine potential
Autor:
Svatopluk Rehak, Kristyna Zaviskova, Karolina Turnovcova, Lucia Machova Urdzikova, Petr Krupa, Jana Dubisova, Irena Vackova, Pavla Jendelova, Zuzana Kočí, Šárka Kubinová, Jiri Ruzicka
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 5; Pages: 1503
International Journal of Molecular Sciences; Volume 19; Issue 5; Pages: 1503
Human mesenchymal stem cells derived from Wharton’s jelly (WJ-MSCs) were used for the treatment of the ischemic-compression model of spinal cord injury in rats. To assess the effectivity of the treatment, different dosages (0.5 or 1.5 million cells