Cardiac biomarkers and left ventricular systolic function in former very preterm infants and term controls at preschool age

Autor: Michaela Höck, Anna Posod, Irena Odri Komazec, Elke Griesmaier, Elisabeth Ralser, Ulrike Pupp-Peglow, Ursula Kiechl-Kohlendorfer

Publikováno v: Frontiers in Pediatrics, Vol 12 (2024)

IntroductionDue to improvements in perinatal care, survival rates of preterm infants have improved during the last decades. However, these infants remain at risk of developing cardiovascular sequelae later in life. This study aimed to investigate the

Externí odkaz: https://doaj.org/article/22d54287708141aaba0c46c0a0fd39c2

Amino Acid and Phospholipid Metabolism as an Indicator of Inflammation and Subtle Cardiomyopathy in Patients with Marfan Syndrome

Autor: Lisa Bartenbach, Thomas Karall, Jakob Koch, Markus Andreas Keller, Herbert Oberacher, Sabine Scholl-Bürgi, Daniela Karall, Gregor Oemer, Daniela Baumgartner, Katharina Meinel, Safwat Aly, Irena Odri-Komazec, Ralf Geiger, Miriam Michel

Publikováno v: Metabolites, Vol 11, Iss 12, p 805 (2021)

Patients with Marfan syndrome (MFS) have an increased risk of aortic aneurysm formation, dissection and development of a subtle cardiomyopathy. We analyzed amino acid and lipid metabolic pathways in MFS patients, seeking biomarker patterns as potenti

Externí odkaz: https://doaj.org/article/e2232528ea284ae09b054ed9496db46c

Former Very Preterm Infants Show an Unfavorable Cardiovascular Risk Profile at a Preschool Age.

Autor: Anna Posod, Irena Odri Komazec, Katrin Kager, Ulrike Pupp Peglow, Elke Griesmaier, Elisabeth Schermer, Philipp Würtinger, Daniela Baumgartner, Ursula Kiechl-Kohlendorfer

Publikováno v: PLoS ONE, Vol 11, Iss 12, p e0168162 (2016)

Cardiovascular disease is the leading cause of death worldwide. Evidence points towards an unfavorable cardiovascular risk profile of former preterm infants in adolescence and adulthood. The aim of this study was to determine whether cardiovascular r

Externí odkaz: https://doaj.org/article/293685c7599245699d157daa5a7786b8

Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial

Autor: Jacqueline Halton, Leonardo R Brandão, Matteo Luciani, Lisa Bomgaars, Elizabeth Chalmers, Lesley G Mitchell, Ildar Nurmeev, Anjali Sharathkumar, Pavel Svirin, Kirill Gorbatikov, Igor Tartakovsky, Monika Simetzberger, Fenglei Huang, Zhichao Sun, Jörg Kreuzer, Savion Gropper, Paul Reilly, Martina Brueckmann, Manuela Albisetti, Asiya Safina, Ondrej Zapletal, Tomas Kuhn, Tomas Votava, Judy Felgenhauer, Ali Amid, Paola Saracco, Csongor Kiss, Susan Halimeh, Madlen Reschke, Beate Wulff, Michele David, Zbynek Novak, Inna Trunina, Tony Frisk, Heidi Glosli, Andreas Groll, Olga Lvova, Ilgen Sasmaz, Darintr Sosothikul, Virginija Zilinskaite, Erin Cockrell, Valeriy Digtyar, Ivana Hadacova, Sauli Palmu, Anjali Pawar, Joyce Maria Annichino Bizzacchi, Umran Caliskan, Tiraje Celkan, Dmytro Dmytriiev, Colleen Harkins Druzgal, Graciela Onelda Elena, Antonis Kattamis, Ramazan Kaan Kavakli, Christoph Male, Nihal Ozdemir, An Van Damme, Tatiana Zvereva, Aanen Aarli, Rogelio Alejandro Paredes Aguilera, Selin Aytac, Jorge Carneiro, Antonio Chistolini, Maria Gabriela Mazzucconi, Fernando Corrales-Medina, Francis Couturaud, Stacey E Croteau, Cameron Trenor III, Michael Damgaard, Natalia Dixon, Anna Galustyan, Jiri Hak, Marianne Hoffmann, Alphan Kupesiz, Veerle Labarque, Christel van Geet, Ming-Chih Lin, Yun-Ching Fu, Sandra Loggetto, Veerle Mondelaers, Irena Odri-Komazec, Shoshana Revel-Vilk, Julian Sevilla, Luciano Fuzzato Silva, José Kerr Saraiva, Fernando Felix Montes Tapia, Wendy Woods-Swafford

Publikováno v: The Lancet. Haematology, Vol. 8, no.1, p. e22-e33 (2021)

BACKGROUND: Dabigatran etexilate is a direct oral anticoagulant with potential to overcome the limitations of standard of care in children with venous thromboembolism. The aims of this clinical trial were to study the appropriateness of a paediatric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6576a5afe58bf10852f806c3c8eb49
https://hdl.handle.net/2078.1/260410

Targeted metabolomic analysis of serum amino acids in the adult Fontan patient with a dominant left ventricle

Autor: Andreas Entenmann, Miriam Michel, Ralf Geiger, Sabine Scholl-Bürgi, Irena Odri Komazec, Manuela Zlamy, Daniela Karall, Mark Gordian Adam, Udo Müller, Karl-Otto Dubowy, Christina Salvador, Kai Thorsten Laser, Christian Niederwanger

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)

Growing interest lies in the assessment of the metabolic status of patients with a univentricular circulation after Fontan operation, especially in changes of amino acid metabolism. Using targeted metabolomic examinations, we investigated amino acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c1d948b97bffb087b5484f1fe3d8b8
https://pubmed.ncbi.nlm.nih.gov/32488174