Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Irena Nalepa"'
Publikováno v:
Data in Brief, Vol 53, Iss , Pp 110242- (2024)
Particulate matter (PM) present in the air pollution increases morbidity and mortality due to several reasons. The dataset presents a comparative analysis of nebulization process of Fe2O3 and SiO2 nanoparticles or crude PM (NIST1648a) and that with r
Externí odkaz:
https://doaj.org/article/1ee19cae7e0e4afbb8ad3c83ef7d1ffe
Autor:
Adam Bielawski, Agnieszka Zelek-Molik, Katarzyna Rafa-Zabłocka, Marta Kowalska, Piotr Gruca, Mariusz Papp, Irena Nalepa
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 243 (2023)
The HSP70 and HSP90 family members belong to molecular chaperones that exhibit protective functions during the cellular response to stressful agents. We investigated whether the exposure of rats to chronic mild stress (CMS), a validated model of depr
Externí odkaz:
https://doaj.org/article/60a1317bbd4e46318e4ade204692010e
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Air pollution is regarded as an important risk factor for many diseases that affect a large proportion of the human population. To date, accumulating reports have noted that particulate matter (PM) is closely associated with the course of cardiopulmo
Externí odkaz:
https://doaj.org/article/63ead3290ca94616885015cfe909a618
Autor:
Adam Roman, Michał Korostyński, Monika Jankowska-Kieltyka, Marcin Piechota, Jacek Hajto, Irena Nalepa
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1100 (2022)
Despite the variable chemical and physical characteristics of particulate air pollutants, inflammation and oxidative stress have been identified as common mechanisms for cell damage and negative health influences. These effects are produced by organi
Externí odkaz:
https://doaj.org/article/688b6ffbcc7646e386ce1f058c51345b
Autor:
Anna Piotrowska, Ewelina Rojewska, Katarzyna Pawlik, Grzegorz Kreiner, Agata Ciechanowska, Wioletta Makuch, Irena Nalepa, Joanna Mika
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Recently, the role of CXCR2 in nociception has been noted. Our studies provide new evidence that the intrathecal administration of its CINC ligands (Cytokine-Induced Neutrophil Chemoattractant; CXCL1-3) induces pain-like behavior in naïve mice, and
Externí odkaz:
https://doaj.org/article/3c13eac700504f87a0d90ab6914cf6e9
Autor:
Katarzyna Rafa–Zabłocka, Grzegorz Kreiner, Monika Bagińska, Justyna Kuśmierczyk, Rosanna Parlato, Irena Nalepa
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Evidence exists that chronic antidepressant therapy enhances CREB levels and activity. Nevertheless, the data are not conclusive, as previous analysis of transgenic mouse models has suggested that CREB inactivation in fact contributes to ant
Externí odkaz:
https://doaj.org/article/a1b7e3eb2dd2473daa4f073cdd043deb
Autor:
Monika Jankowska-Kieltyka, Adam Roman, Magdalena Mikrut, Marta Kowalska, Rudi van Eldik, Irena Nalepa
Publikováno v:
Toxics, Vol 9, Iss 9, p 205 (2021)
Exposure to air pollution from various airborne particulate matter (PM) is regarded as a potential health risk. Airborne PM penetrates the lungs, where it is taken up by macrophages, what results in macrophage activation and can potentially lead to n
Externí odkaz:
https://doaj.org/article/4939ca758d30498aac2c6f4b5689cbb0
Autor:
Piotr Chmielarz, Justyna Kuśmierczyk, Katarzyna Rafa-Zabłocka, Katarzyna Chorązka, Marta Kowalska, Grzegorz Satała, Irena Nalepa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4817 (2021)
Currently utilized antidepressants have limited effectiveness and frequently incur undesired effects. Most antidepressants are thought to act via the inhibition of monoamine reuptake; however, direct binding to monoaminergic receptors has been propos
Externí odkaz:
https://doaj.org/article/0c15dfbd64e34ca79e66372f4a6a9dd8
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Neurotrophic factors are regarded as crucial regulatory components in neuronal plasticity and are postulated to play an important role in depression pathology. The abundant expression of brain-derived neurotrophic factor (BDNF) in various brain struc
Externí odkaz:
https://doaj.org/article/83175f17965b447abeca5f30febeffe7
Autor:
Agnieszka Zelek-Molik, Bartosz Bobula, Anna Gądek-Michalska, Katarzyna Chorązka, Adam Bielawski, Justyna Kuśmierczyk, Marcin Siwiec, Michał Wilczkowski, Grzegorz Hess, Irena Nalepa
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 294 (2021)
This study demonstrates how exposure to psychosocial crowding stress (CS) for 3, 7, and 14 days affects glutamate synapse functioning and signal transduction in the frontal cortex (FC) of rats. CS effects on synaptic activity were evaluated in FC sli
Externí odkaz:
https://doaj.org/article/7afb7fe8de6243ccaca5fdfc8eec05ca